ID   ARD1_LEIDO              Reviewed;         186 AA.
AC   Q05885;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=N-terminal acetyltransferase complex ARD1 subunit homolog;
DE            EC=2.3.1.-;
GN   Name=ARD1;
OS   Leishmania donovani.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania.
OX   NCBI_TaxID=5661;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Ld4;
RX   PubMed=8378337; DOI=10.1073/pnas.90.18.8609;
RA   Ryan K.A., Garraway L.A., Descoteaux A., Turco S.J., Beverley S.M.;
RT   "Isolation of virulence genes directing surface glycosyl-
RT   phosphatidylinositol synthesis by functional complementation of
RT   Leishmania.";
RL   Proc. Natl. Acad. Sci. U.S.A. 90:8609-8613(1993).
CC   -!- FUNCTION: Seems to be involved in N-acetylation. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the acetyltransferase family. ARD1 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; L11348; AAA03082.1; -; Unassigned_DNA.
DR   AlphaFoldDB; Q05885; -.
DR   SMR; Q05885; -.
DR   VEuPathDB; TriTrypDB:LdBPK_250020.1; -.
DR   VEuPathDB; TriTrypDB:LdCL_250005100; -.
DR   VEuPathDB; TriTrypDB:LDHU3_25.0030; -.
DR   GO; GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR013653; FR47.
DR   InterPro; IPR000182; GNAT_dom.
DR   Pfam; PF08445; FR47; 1.
DR   SUPFAM; SSF55729; SSF55729; 1.
DR   PROSITE; PS51186; GNAT; 1.
PE   3: Inferred from homology;
KW   Acyltransferase; Transferase.
FT   CHAIN           1..186
FT                   /note="N-terminal acetyltransferase complex ARD1 subunit
FT                   homolog"
FT                   /id="PRO_0000074531"
FT   DOMAIN          2..161
FT                   /note="N-acetyltransferase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00532"
SQ   SEQUENCE   186 AA;  21684 MW;  434579084B1EEA8C CRC64;
     MTTYRRMTLC DTLQFNFVNL DQLTETYNTS FYGEYVTHWP EYQRMCVHPT TNIPMAYTLG
     KAEGQGEDYH GHVSAVSVAP TFRRVALGET LMAELAQMSE LVHNAYFVDL FVRKSNQVAQ
     DMYHRLGYIV YRTVLNYYHG DGPKGPFKSD EDALDMRLAL RRDKERRKSS VIPLDRPIKP
     EELEWV