LDL3_ORYSI
ID LDL3_ORYSI Reviewed; 811 AA.
AC Q01H90; A2XWD9;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 14-NOV-2006, sequence version 1.
DT 03-AUG-2022, entry version 81.
DE RecName: Full=Lysine-specific histone demethylase 1 homolog 3;
DE EC=1.-.-.-;
DE AltName: Full=Flavin-containing amine oxidase domain-containing protein 3;
DE AltName: Full=Protein FLOWERING LOCUS D-LIKE;
DE AltName: Full=Protein LSD1-LIKE 3;
GN ORFNames=B0103C08-B0602B01.13, OsI_016382;
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Guang-Lu-Ai No.4;
RX PubMed=12447439; DOI=10.1038/nature01183;
RA Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA Li J., Hong G., Xue Y., Han B.;
RT "Sequence and analysis of rice chromosome 4.";
RL Nature 420:316-320(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- FUNCTION: Probable histone demethylase. {ECO:0000250}.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000305};
CC -!- SIMILARITY: Belongs to the flavin monoamine oxidase family.
CC {ECO:0000305}.
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DR EMBL; CR855240; CAH68056.1; -; Genomic_DNA.
DR EMBL; CM000129; EAY95149.1; -; Genomic_DNA.
DR AlphaFoldDB; Q01H90; -.
DR SMR; Q01H90; -.
DR STRING; 39946.Q01H90; -.
DR PRIDE; Q01H90; -.
DR EnsemblPlants; BGIOSGA014556-TA; BGIOSGA014556-PA; BGIOSGA014556.
DR Gramene; BGIOSGA014556-TA; BGIOSGA014556-PA; BGIOSGA014556.
DR HOGENOM; CLU_004498_5_0_1; -.
DR OMA; IVHTIRY; -.
DR Proteomes; UP000007015; Chromosome 4.
DR GO; GO:0110165; C:cellular anatomical entity; IEA:UniProt.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:UniProt.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0016570; P:histone modification; IEA:UniProt.
DR Gene3D; 1.10.10.10; -; 1.
DR Gene3D; 3.50.50.60; -; 1.
DR InterPro; IPR002937; Amino_oxidase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR007526; SWIRM.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR Pfam; PF01593; Amino_oxidase; 1.
DR Pfam; PF04433; SWIRM; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR SUPFAM; SSF51905; SSF51905; 1.
DR PROSITE; PS50934; SWIRM; 1.
PE 3: Inferred from homology;
KW Chromatin regulator; FAD; Flavoprotein; Oxidoreductase; Reference proteome.
FT CHAIN 1..811
FT /note="Lysine-specific histone demethylase 1 homolog 3"
FT /id="PRO_0000342898"
FT DOMAIN 88..189
FT /note="SWIRM"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00247"
FT REGION 1..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 790..811
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..36
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 227
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000250"
FT BINDING 229
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000250"
FT BINDING 235
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000250"
FT BINDING 609
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000250"
SQ SEQUENCE 811 AA; 87289 MW; 9629B3920B82EC1F CRC64;
MSDQPPPYTP LPLLSSFPPN PYPDQTPDPA STPTLVLPNP AFPNKRKRTG FRRKLPSGSP
AAPVAVAASP SAQPPPRASA ADDIIVINRE PTAEAVTALT AGFPADSLTD EEIEAGVVSD
VGGIEQVNYI LIRNHLLTRW RETFNSWLAK ESFATLIPPH CDHLLNAAYS FLVSHGHINF
GVAPAIKERI PKEPTRHNTV IVVGAGLAGL AAARQLVAFG FKVVVLEGRK RCGGRVYTKK
MEGGGRSAAG DLGGSVLTGT FGNPLGIVAK QLGLPMHKIR DKCPLYRPDG SPVDPEVDKK
VEGTFNKLLD KSSLLRASMG DVAMDVSLGA ALETLRQTDG DLSTDQEMNL FNWHLANLEY
ANAGLLSKLS LAFWDQDDPY DMGGDHCFLP GGNGRLVQAL AENVPIVYER TVHTIRNGGD
GVQVVVNGGQ VYEGDMALCT VPLGVLKNGG VKFVPELPQR KLDSIKRLGF GLLNKVAMLF
PHVFWSTDLD TFGHLTEDPS HRGEFFLFYS YATVAGGPLL MALVAGEAAH NFETTPPTDA
VSSVLKILRG IYEPQGIEVP DPLQSVCTRW GTDSFSLGSY SHVAVGASGD DYDILAESVG
DGRLFFAGEA TTRRYPATMH GAFISGLREA ANITLHANAR AAKSKVEKGP STNTQACAAL
LMDLFRQPDL EFGSFSVIFG GQASDPKSPA ILKVELGGPR KKGATEGGKA DQHHSNKLLF
QQLQSHFNQQ QQLYVYTLLS RQQAMELREV RGGDEMRLHY LCEKLGVKLV GRKGLGPGAD
AVIASIKAER NSSRTKTRPS KLKIGIPKSK S
