LEA6_ARATH
ID LEA6_ARATH Reviewed; 134 AA.
AC Q39138; Q42167;
DT 02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Late embryogenesis abundant protein 6 {ECO:0000303|PubMed:18318901};
DE AltName: Full=Late embryogenesis abundant protein 4-1 {ECO:0000303|PubMed:20668063};
DE Short=AtLEA4-1 {ECO:0000303|PubMed:20668063};
GN Name=LEA6 {ECO:0000303|PubMed:18318901};
GN Synonyms=LEA4-1 {ECO:0000303|PubMed:20668063};
GN OrderedLocusNames=At1g32560 {ECO:0000312|Araport:AT1G32560};
GN ORFNames=T9G5.2 {ECO:0000312|EMBL:AAG51244.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RA Grellet F., Cooke R., Laudi M., Raynal M., Delseny M.;
RT "A.thaliana mRNA for LEA protein.";
RL Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-103.
RC STRAIN=cv. Columbia; TISSUE=Dry seed;
RX PubMed=8580968; DOI=10.1046/j.1365-313x.1996.09010101.x;
RA Cooke R., Raynal M., Laudie M., Grellet F., Delseny M., Morris P.-C.,
RA Guerrier D., Giraudat J., Quigley F., Clabault G., Li Y.-F., Mache R.,
RA Krivitzky M., Gy I.J.-J., Kreis M., Lecharny A., Parmentier Y., Marbach J.,
RA Fleck J., Clement B., Philipps G., Herve C., Bardet C., Tremousaygue D.,
RA Lescure B., Lacomme C., Roby D., Jourjon M.-F., Chabrier P.,
RA Charpenteau J.-L., Desprez T., Amselem J., Chiapello H., Hoefte H.;
RT "Further progress towards a catalogue of all Arabidopsis genes: analysis of
RT a set of 5000 non-redundant ESTs.";
RL Plant J. 9:101-124(1996).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18318901; DOI=10.1186/1471-2164-9-118;
RA Hundertmark M., Hincha D.K.;
RT "LEA (late embryogenesis abundant) proteins and their encoding genes in
RT Arabidopsis thaliana.";
RL BMC Genomics 9:118-118(2008).
RN [7]
RP FUNCTION, DEVELOPMENTAL STAGE, AND INDUCTION.
RX PubMed=20668063; DOI=10.1104/pp.110.158964;
RA Olvera-Carrillo Y., Campos F., Reyes J.L., Garciarrubio A.,
RA Covarrubias A.A.;
RT "Functional analysis of the group 4 late embryogenesis abundant proteins
RT reveals their relevance in the adaptive response during water deficit in
RT Arabidopsis.";
RL Plant Physiol. 154:373-390(2010).
CC -!- FUNCTION: Involved dehydration tolerance. Involved in the adaptive
CC response of vascular plants to withstand water deficit
CC (PubMed:20668063). May possess chaperone-like activity under water
CC deficit (By similarity). {ECO:0000250|UniProtKB:Q96273,
CC ECO:0000269|PubMed:20668063}.
CC -!- DEVELOPMENTAL STAGE: Expressed during embryo development and in dry
CC seed. Expression decreases significantly after seed germination.
CC {ECO:0000269|PubMed:20668063}.
CC -!- INDUCTION: By dehydration stress. {ECO:0000269|PubMed:20668063}.
CC -!- SIMILARITY: Belongs to the LEA type 1 family. {ECO:0000305}.
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DR EMBL; X89505; CAA61676.1; -; mRNA.
DR EMBL; AC055769; AAG51244.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31503.1; -; Genomic_DNA.
DR EMBL; AY063826; AAL36182.1; -; mRNA.
DR EMBL; AY096424; AAM20064.1; -; mRNA.
DR EMBL; Z27059; CAA81577.1; -; mRNA.
DR PIR; S71249; S71249.
DR RefSeq; NP_174534.1; NM_102991.4.
DR AlphaFoldDB; Q39138; -.
DR SMR; Q39138; -.
DR STRING; 3702.AT1G32560.1; -.
DR PaxDb; Q39138; -.
DR PRIDE; Q39138; -.
DR ProteomicsDB; 230137; -.
DR EnsemblPlants; AT1G32560.1; AT1G32560.1; AT1G32560.
DR GeneID; 840150; -.
DR Gramene; AT1G32560.1; AT1G32560.1; AT1G32560.
DR KEGG; ath:AT1G32560; -.
DR Araport; AT1G32560; -.
DR TAIR; locus:2206629; AT1G32560.
DR eggNOG; ENOG502S735; Eukaryota.
DR HOGENOM; CLU_134661_0_0_1; -.
DR InParanoid; Q39138; -.
DR OMA; AEANMDM; -.
DR OrthoDB; 1639513at2759; -.
DR PhylomeDB; Q39138; -.
DR PRO; PR:Q39138; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q39138; baseline and differential.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0009506; C:plasmodesma; HDA:TAIR.
DR GO; GO:0009793; P:embryo development ending in seed dormancy; IEA:InterPro.
DR GO; GO:0006970; P:response to osmotic stress; IMP:TAIR.
DR GO; GO:0009414; P:response to water deprivation; IMP:TAIR.
DR GO; GO:0048316; P:seed development; IMP:TAIR.
DR InterPro; IPR005513; LEA_1.
DR PANTHER; PTHR33493; PTHR33493; 1.
DR Pfam; PF03760; LEA_1; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Reference proteome; Stress response.
FT CHAIN 1..134
FT /note="Late embryogenesis abundant protein 6"
FT /id="PRO_0000438096"
FT REGION 31..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 80..134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 34..70
FT /evidence="ECO:0000255"
FT CONFLICT 54
FT /note="E -> D (in Ref. 5; CAA81577)"
FT /evidence="ECO:0000305"
FT CONFLICT 88..95
FT /note="PQQAPVPA -> SQQASVPS (in Ref. 5; CAA81577)"
FT /evidence="ECO:0000305"
FT CONFLICT 101
FT /note="G -> A (in Ref. 5; CAA81577)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 134 AA; 14891 MW; 99D7B5FD8A215445 CRC64;
MQSAKQKISD MASTAKEKMV ICQAKADEKA ERAMARTKEE KEIAHQRRKA KEAEANMDMH
MAKAAHAEDK LMAKQSHYHV TDHGPHVPQQ APVPAPAPVM GHGYGHNPTG VTSVPPQTYH
PTYPPTGHHN HHHY
