AREA_GIBFU
ID AREA_GIBFU Reviewed; 971 AA.
AC P78688;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1997, sequence version 1.
DT 23-FEB-2022, entry version 86.
DE RecName: Full=Nitrogen regulatory protein areA;
GN Name=AREA;
OS Gibberella fujikuroi (Bakanae and foot rot disease fungus) (Fusarium
OS fujikuroi).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=5127;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=m567;
RX PubMed=10071216; DOI=10.1007/s004380050947;
RA Tudzynski B., Homann V., Feng B., Marzluf G.A.;
RT "Isolation, characterization and disruption of the areA nitrogen regulatory
RT gene of Gibberella fujikuroi.";
RL Mol. Gen. Genet. 261:106-114(1999).
CC -!- FUNCTION: Major nitrogen regulatory protein. Positively acting
CC regulatory gene of nitrogen metabolite repression (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus.
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DR EMBL; Y11006; CAA71897.1; -; Genomic_DNA.
DR eggNOG; KOG1601; Eukaryota.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd00202; ZnF_GATA; 1.
DR Gene3D; 3.30.50.10; -; 1.
DR InterPro; IPR013860; AreA_GATA.
DR InterPro; IPR039355; Transcription_factor_GATA.
DR InterPro; IPR000679; Znf_GATA.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR10071; PTHR10071; 1.
DR Pfam; PF08550; DUF1752; 1.
DR Pfam; PF00320; GATA; 1.
DR PRINTS; PR00619; GATAZNFINGER.
DR SMART; SM00401; ZnF_GATA; 1.
DR PROSITE; PS00344; GATA_ZN_FINGER_1; 1.
DR PROSITE; PS50114; GATA_ZN_FINGER_2; 1.
PE 3: Inferred from homology;
KW Activator; DNA-binding; Metal-binding; Nitrate assimilation; Nucleus;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..971
FT /note="Nitrogen regulatory protein areA"
FT /id="PRO_0000083466"
FT ZN_FING 694..718
FT /note="GATA-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00094"
FT REGION 31..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 144..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 262..426
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 542..695
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 742..959
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 42..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 262..278
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..294
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..313
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 322..374
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 383..419
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 576..609
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 624..695
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 747..833
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 859..873
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 917..959
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 971 AA; 103582 MW; 887DD882141C7453 CRC64;
MSTSVSIATS SPVLTMNPII TEHDFRFPRR PSAWPGAAIH NAPTQRTXNS NRIPNSRDAS
ASFKEHKTDM ATTYSLARQG LGGSALFPFL QNGLADSDRS IDRMQQDDPL ATQVWKFFAR
TKHQLPSQHR MENLTWRMMA LNIRRHKEEQ QQRQDEADAR RKKNMDAGSR AFRLGRPMMQ
SSPSGIAQLR KSSENNLAQP DAMNLDDFIF SDNSGSPINF ASPEGDKMVD DRSGSSMASA
IPIKSRKEPS LQNFVPQSVP VQPAHQATQG SEFNYVNRHL RKTSIDDRRT RKRPANFSPQ
VPAVNSTAAQ NDLDLDSELH DYSLDQPNQA GIPQQSNGSN VPFNIDTFME NDSMVNNGNF
QQNFSFSPST SPMIPHGPFS GMYHNSSVPS ASMSNNNNNS DFYSPPASAY PSNVSTPHPV
PEQEGFYFGS QDARTQRPQG FQQSIGSMLS QQFMYGGSNG NSGSTMFSAP GTASESMSAY
STAPSSFGHI DPSQVFQNEQ AVTSPTIQMP QDNMFSFGAD SDDEDNNAFA DRNVSMQKDM
SSSLDESGAM GWDASLPGQF STQAARFPGG PTRKQVMIGG TTTDFVDNNG DWESNGLERS
QSQSFRGGNL RRQHPKLPRN ASTPVHFGGQ QNGFEQLAQS MQSSPAGDGN GTMSGFSSVA
PSRPSSPPMS KQGSTTNLQA AAGNGNDGNA PTTCTNCFTQ TTPLWRRNPE GQPLCNACGL
FLKLHGVVRP LSLKTDVIKK RNRGSGTNVP VGGSSTRSKK TASTLNSRKN STLSMSTATA
NSTKPNSSNP TPRVTTPPAT SQPPSSKDVD SPVSGTTSGA NTAGSTPNSH FGGPGPSSGA
VGGKGVVPIA AAPPKTSPGP GASSMSMQRP ATASSKRQRR HSKSIGGDVP VSMDIDSPDS
TSSIDGPRPF GSSAGLSSLP GGMSASSFNL NQRPSTLGSA TGMISMSGGQ TSSLIGSSAG
PQEWEWLTMS L
