ID   LEC1_SOLFI              Reviewed;         267 AA.
AC   C0HL89;
DT   25-APR-2018, integrated into UniProtKB/Swiss-Prot.
DT   25-APR-2018, sequence version 1.
DT   25-MAY-2022, entry version 7.
DE   RecName: Full=Lectin SfL-1 {ECO:0000303|PubMed:28970169};
OS   Solieria filiformis (Red alga) (Euhymenia filiformis).
OC   Eukaryota; Rhodophyta; Florideophyceae; Rhodymeniophycidae; Gigartinales;
OC   Solieriaceae; Solieria.
OX   NCBI_TaxID=31449;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 1-12, MASS SPECTROMETRY,
RP   AND IDENTIFICATION BY MASS SPECTROMETRY.
RX   PubMed=28970169; DOI=10.1016/j.ijbiomac.2017.09.116;
RA   Chaves R.P., Silva S.R.D., Nascimento Neto L.G., Carneiro R.F.,
RA   Silva A.L.C.D., Sampaio A.H., Sousa B.L., Cabral M.G., Videira P.A.,
RA   Teixeira E.H., Nagano C.S.;
RT   "Structural characterization of two isolectins from the marine red alga
RT   Solieria filiformis (Kuetzing) P.W. Gabrielson and their anticancer effect
RT   on MCF-7 breast cancer cells.";
RL   Int. J. Biol. Macromol. 107:1320-1329(2018).
CC   -!- FUNCTION: Lectin specific for high mannose N-glycans, recognizes the
CC       branched moiety of these glycans. Does not recognize other types of N-
CC       glycans or monosaccharides. {ECO:0000250|UniProtKB:P84331}.
CC   -!- SUBUNIT: Monomer. {ECO:0000269|PubMed:28970169}.
CC   -!- MASS SPECTROMETRY: Mass=27533; Method=Electrospray;
CC       Evidence={ECO:0000269|PubMed:28970169};
CC   -!- SIMILARITY: Belongs to the bacterial lectin family. {ECO:0000305}.
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DR   AlphaFoldDB; C0HL89; -.
DR   SMR; C0HL89; -.
DR   GO; GO:0005537; F:mannose binding; IEA:UniProtKB-KW.
DR   InterPro; IPR040964; SBD.
DR   Pfam; PF17882; SBD; 4.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Lectin; Mannose-binding; Repeat.
FT   CHAIN           1..267
FT                   /note="Lectin SfL-1"
FT                   /evidence="ECO:0000305"
FT                   /id="PRO_0000444012"
FT   REPEAT          1..67
FT                   /note="1"
FT                   /evidence="ECO:0000303|PubMed:28970169"
FT   REPEAT          68..135
FT                   /note="2"
FT                   /evidence="ECO:0000303|PubMed:28970169"
FT   REPEAT          136..202
FT                   /note="3"
FT                   /evidence="ECO:0000303|PubMed:28970169"
FT   REPEAT          203..267
FT                   /note="4"
FT                   /evidence="ECO:0000303|PubMed:28970169"
FT   REGION          1..267
FT                   /note="4 X approximate tandem repeats"
FT                   /evidence="ECO:0000303|PubMed:28970169"
SQ   SEQUENCE   267 AA;  27552 MW;  F8846C9D1F1CCC62 CRC64;
     GRYTVQNQWG GSSAPWNDAG LWLLGSRANQ NVMDVSVTSS DGGATLTGTM TYSGEGPIGF
     KGTRRGDSNN YDVENQWGGS SAPWHAGGTF VIGSRSGQGV VAVDVNSSDG GKTLTGTMTY
     ANEGPIGFKG TQSGGDSYNV ENQWGGSSAP WNKAGAWALG DRDGQGVIGV DVTSSDGGKT
     LTGTMQYQNE GPIGFKGTST GGSNYKVENQ WGGSSAPWNP AGNWLIGDRH NQNIVAVKVT
     SSDNGKTLGG TCTYEREGPI GFKGTAI