ID   AREA_PENRO              Reviewed;         860 AA.
AC   O13508;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-1998, sequence version 2.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Nitrogen regulatory protein areA;
DE   AltName: Full=Nitrogen regulator nmc;
GN   Name=AREA; Synonyms=NMC;
OS   Penicillium roqueforti.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=5082;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=P2;
RA   Gente S., Poussereau N., Fevre M.;
RL   Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Major nitrogen regulatory protein.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
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DR   EMBL; AJ001530; CAA04815.1; -; Genomic_DNA.
DR   AlphaFoldDB; O13508; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   CDD; cd00202; ZnF_GATA; 1.
DR   Gene3D; 3.30.50.10; -; 1.
DR   InterPro; IPR013860; AreA_GATA.
DR   InterPro; IPR011420; AreA_N.
DR   InterPro; IPR039355; Transcription_factor_GATA.
DR   InterPro; IPR000679; Znf_GATA.
DR   InterPro; IPR013088; Znf_NHR/GATA.
DR   PANTHER; PTHR10071; PTHR10071; 1.
DR   Pfam; PF07573; AreA_N; 1.
DR   Pfam; PF08550; DUF1752; 1.
DR   Pfam; PF00320; GATA; 1.
DR   PRINTS; PR00619; GATAZNFINGER.
DR   SMART; SM00401; ZnF_GATA; 1.
DR   PROSITE; PS00344; GATA_ZN_FINGER_1; 1.
DR   PROSITE; PS50114; GATA_ZN_FINGER_2; 1.
PE   4: Predicted;
KW   Activator; DNA-binding; Metal-binding; Nitrate assimilation; Nucleus;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..860
FT                   /note="Nitrogen regulatory protein areA"
FT                   /id="PRO_0000083468"
FT   ZN_FING         660..684
FT                   /note="GATA-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00094"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          116..159
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          174..193
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          559..600
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          612..658
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          706..850
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        124..140
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        628..643
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        708..761
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        791..806
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   860 AA;  91616 MW;  2B8BF0DDCDC1BA68 CRC64;
     MDGIHHGGHG RARPSHPMAF PDFDADSHMM SDDFSLDTPF SPSGSSNAND TVLGNSIFPE
     WTNGVSRGDS PDEMQRKDPL GAQIWKLYTR TKSQLPNQER MENLTWRMMA MNLKRKEREQ
     QARASETLSP TPSGIAQMRL SDQPSPAGGD LAHDTTSDPM NLDDFIVPFD SPAEHSSHPI
     DRHFTATPTG SIPIKSRKDH AMMDSSTAAS FPHPPQDQRT NSEFGYVARR VRKTSVDDRQ
     FFAGLSVPTR KRPAEASPQV PPVSNAMMAQ HSELSSALPD YSLDHPPSAY ALSGNGTVGP
     RRPQHHHTHS NIPYGLDTYG ISENHGLNSA GSYQQNFHFS PSDSPMTAGN PFSSLYAQTP
     LASSLNSTEF FSPPPSGYQS TVSTPQPIYE GEQSIFFSDA PSAESHTQRR IPNYIQQRQS
     NLSASLQPRY MYNMSNGESH SGSAVTGPPT THVSGFSVPP PQHINPSQVL GHGEFSTTAP
     SSSMFTFGGD SDNEDDDGNF GEGGGMTMPN DFASLDESGD MSAGLHWDGG FPGSIHSLPG
     FNAQHRKHVT IGSTDMIDGP PEWNQGGTLG RAHGSAASVS EVRNQNQDPR RYGKVPRTAS
     TPNAAALLRQ SLNGSASGPP TNHPSPSTPP ESGLSSAVPS RPGSPGGSKN GDPNAGPTTC
     TNCFTQTTPL WRRNPEGQPL CNACGLFLKL HGVVRPLSLK TDVIKKRNRS SASTLAVGTS
     RSSKKSSRKN SIQHAPSTSI SSRMNTSESP PSMNGSSSLG KTGVVPIAAA PPKSGPPAGV
     AQARAGVQVA PRRQRRLEKA PTGSDPDAKD SPKSAAPPSR SKVLPLAPAM APPAAANPAN
     HNIAGGQGAS QEWEWLTMSL