ID   LEC8_CAEEL              Reviewed;         180 AA.
AC   Q09610; Q9GNP9;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   27-MAY-2002, sequence version 2.
DT   03-AUG-2022, entry version 129.
DE   RecName: Full=Probable galaptin lec-8;
GN   Name=lec-8; ORFNames=R07B1.10;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Hirabayashi J., Hayama K., Kasai K.;
RT   "Novel galectins found in C. elegans.";
RL   Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
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DR   EMBL; AB038499; BAB11964.1; -; mRNA.
DR   EMBL; Z48621; CAA88548.2; -; Genomic_DNA.
DR   PIR; T24001; T24001.
DR   RefSeq; NP_509649.1; NM_077248.4.
DR   AlphaFoldDB; Q09610; -.
DR   SMR; Q09610; -.
DR   BioGRID; 46113; 1.
DR   STRING; 6239.R07B1.10; -.
DR   EPD; Q09610; -.
DR   PaxDb; Q09610; -.
DR   PeptideAtlas; Q09610; -.
DR   EnsemblMetazoa; R07B1.10.1; R07B1.10.1; WBGene00002271.
DR   GeneID; 181198; -.
DR   KEGG; cel:CELE_R07B1.10; -.
DR   UCSC; R07B1.10.1; c. elegans.
DR   CTD; 181198; -.
DR   WormBase; R07B1.10; CE26721; WBGene00002271; lec-8.
DR   eggNOG; KOG3587; Eukaryota.
DR   GeneTree; ENSGT00750000118601; -.
DR   HOGENOM; CLU_037794_3_1_1; -.
DR   InParanoid; Q09610; -.
DR   OMA; VNFRFEH; -.
DR   OrthoDB; 829777at2759; -.
DR   PhylomeDB; Q09610; -.
DR   Reactome; R-CEL-381426; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs).
DR   Reactome; R-CEL-6798695; Neutrophil degranulation.
DR   Reactome; R-CEL-8957275; Post-translational protein phosphorylation.
DR   PRO; PR:Q09610; -.
DR   Proteomes; UP000001940; Chromosome X.
DR   Bgee; WBGene00002271; Expressed in adult organism and 4 other tissues.
DR   GO; GO:0031410; C:cytoplasmic vesicle; IDA:WormBase.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR   GO; GO:0051861; F:glycolipid binding; IDA:WormBase.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IC:WormBase.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; HEP:WormBase.
DR   GO; GO:0009636; P:response to toxic substance; IMP:WormBase.
DR   CDD; cd00070; GLECT; 1.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR044156; Galectin-like.
DR   InterPro; IPR001079; Galectin_CRD.
DR   PANTHER; PTHR11346; PTHR11346; 1.
DR   Pfam; PF00337; Gal-bind_lectin; 1.
DR   SMART; SM00908; Gal-bind_lectin; 1.
DR   SMART; SM00276; GLECT; 1.
DR   SUPFAM; SSF49899; SSF49899; 1.
DR   PROSITE; PS51304; GALECTIN; 1.
PE   2: Evidence at transcript level;
KW   Lectin; Reference proteome.
FT   CHAIN           1..180
FT                   /note="Probable galaptin lec-8"
FT                   /id="PRO_0000076966"
FT   DOMAIN          11..138
FT                   /note="Galectin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00639"
SQ   SEQUENCE   180 AA;  20447 MW;  FA01D616035CDF69 CRC64;
     MHTINSPDVP SAHAIREQLR AGSEIHVRGH VTHKHHKDFS VELLSGPHIV LHVNFRFEHD
     HIVAMNTCTN GAWGAEIRHH NPLKHHDHFN LSIHVHEGYY HISVNGEHLA DFPHRFPVES
     VQAIGLKGAA HIDEISFSGF EFGVDWNSQH DFGHAGYNSY GTETYVAPVF QETHSYNAYF