LEC8_MEDTR
ID LEC8_MEDTR Reviewed; 275 AA.
AC Q2PP75; A9YWS3;
DT 17-JUN-2020, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 1.
DT 25-MAY-2022, entry version 76.
DE RecName: Full=Lectin 8 {ECO:0000303|PubMed:16134889};
DE Short=MtLec8 {ECO:0000303|PubMed:16134889};
DE AltName: Full=Agglutinin LEC8 {ECO:0000305};
DE Flags: Precursor;
GN Name=LEC8 {ECO:0000303|PubMed:16134889};
GN OrderedLocusNames=MTR_5g031090 {ECO:0000312|EMBL:AES95924.1};
GN ORFNames=MtrunA17_Chr5g0411731 {ECO:0000312|EMBL:RHN54884.1};
OS Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX NCBI_TaxID=3880;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND INDUCTION BY ARBUSCULAR MYCORRHIZAL FUNGI.
RC STRAIN=cv. Jemalong A17;
RX PubMed=16134889; DOI=10.1094/mpmi-18-0771;
RA Frenzel A., Manthey K., Perlick A.M., Meyer F., Puehler A., Kuester H.,
RA Krajinski F.;
RT "Combined transcriptome profiling reveals a novel family of arbuscular
RT mycorrhizal-specific Medicago truncatula lectin genes.";
RL Mol. Plant Microbe Interact. 18:771-782(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Jemalong A17;
RX PubMed=16273388; DOI=10.1007/s00438-005-0057-9;
RA Kevei Z., Seres A., Kereszt A., Kalo P., Kiss P., Toth G., Endre G.,
RA Kiss G.B.;
RT "Significant microsynteny with new evolutionary highlights is detected
RT between Arabidopsis and legume model plants despite the lack of
RT macrosynteny.";
RL Mol. Genet. Genomics 274:644-657(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Jemalong A17;
RX PubMed=22089132; DOI=10.1038/nature10625;
RA Young N.D., Debelle F., Oldroyd G.E.D., Geurts R., Cannon S.B.,
RA Udvardi M.K., Benedito V.A., Mayer K.F.X., Gouzy J., Schoof H.,
RA Van de Peer Y., Proost S., Cook D.R., Meyers B.C., Spannagl M., Cheung F.,
RA De Mita S., Krishnakumar V., Gundlach H., Zhou S., Mudge J., Bharti A.K.,
RA Murray J.D., Naoumkina M.A., Rosen B., Silverstein K.A.T., Tang H.,
RA Rombauts S., Zhao P.X., Zhou P., Barbe V., Bardou P., Bechner M.,
RA Bellec A., Berger A., Berges H., Bidwell S., Bisseling T., Choisne N.,
RA Couloux A., Denny R., Deshpande S., Dai X., Doyle J.J., Dudez A.-M.,
RA Farmer A.D., Fouteau S., Franken C., Gibelin C., Gish J., Goldstein S.,
RA Gonzalez A.J., Green P.J., Hallab A., Hartog M., Hua A., Humphray S.J.,
RA Jeong D.-H., Jing Y., Jocker A., Kenton S.M., Kim D.-J., Klee K., Lai H.,
RA Lang C., Lin S., Macmil S.L., Magdelenat G., Matthews L., McCorrison J.,
RA Monaghan E.L., Mun J.-H., Najar F.Z., Nicholson C., Noirot C.,
RA O'Bleness M., Paule C.R., Poulain J., Prion F., Qin B., Qu C., Retzel E.F.,
RA Riddle C., Sallet E., Samain S., Samson N., Sanders I., Saurat O.,
RA Scarpelli C., Schiex T., Segurens B., Severin A.J., Sherrier D.J., Shi R.,
RA Sims S., Singer S.R., Sinharoy S., Sterck L., Viollet A., Wang B.-B.,
RA Wang K., Wang M., Wang X., Warfsmann J., Weissenbach J., White D.D.,
RA White J.D., Wiley G.B., Wincker P., Xing Y., Yang L., Yao Z., Ying F.,
RA Zhai J., Zhou L., Zuber A., Denarie J., Dixon R.A., May G.D.,
RA Schwartz D.C., Rogers J., Quetier F., Town C.D., Roe B.A.;
RT "The Medicago genome provides insight into the evolution of rhizobial
RT symbioses.";
RL Nature 480:520-524(2011).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Jemalong A17;
RX PubMed=24767513; DOI=10.1186/1471-2164-15-312;
RA Tang H., Krishnakumar V., Bidwell S., Rosen B., Chan A., Zhou S.,
RA Gentzbittel L., Childs K.L., Yandell M., Gundlach H., Mayer K.F.,
RA Schwartz D.C., Town C.D.;
RT "An improved genome release (version Mt4.0) for the model legume Medicago
RT truncatula.";
RL BMC Genomics 15:312-312(2014).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Jemalong A17;
RX PubMed=30397259; DOI=10.1038/s41477-018-0286-7;
RA Pecrix Y., Staton S.E., Sallet E., Lelandais-Briere C., Moreau S.,
RA Carrere S., Blein T., Jardinaud M.F., Latrasse D., Zouine M., Zahm M.,
RA Kreplak J., Mayjonade B., Satge C., Perez M., Cauet S., Marande W.,
RA Chantry-Darmon C., Lopez-Roques C., Bouchez O., Berard A., Debelle F.,
RA Munos S., Bendahmane A., Berges H., Niebel A., Buitink J., Frugier F.,
RA Benhamed M., Crespi M., Gouzy J., Gamas P.;
RT "Whole-genome landscape of Medicago truncatula symbiotic genes.";
RL Nat. Plants 4:1017-1025(2018).
CC -!- FUNCTION: May be involved in arbuscular mycorrhizal (AM) symbiosis with
CC AM fungi. {ECO:0000305|PubMed:16134889}.
CC -!- INDUCTION: Accumulates in roots during colonization by arbuscular
CC mycorrhizal (AM) fungi (e.g. Glomus intraradices).
CC {ECO:0000269|PubMed:16134889}.
CC -!- SIMILARITY: Belongs to the leguminous lectin family. {ECO:0000305}.
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DR EMBL; DQ314210; ABC47814.1; -; mRNA.
DR EMBL; EU306659; ABY48145.1; -; Genomic_DNA.
DR EMBL; CM001221; AES95924.1; -; Genomic_DNA.
DR EMBL; PSQE01000005; RHN54884.1; -; Genomic_DNA.
DR RefSeq; XP_003612966.1; XM_003612918.2.
DR AlphaFoldDB; Q2PP75; -.
DR SMR; Q2PP75; -.
DR STRING; 3880.AES95924; -.
DR EnsemblPlants; AES95924; AES95924; MTR_5g031090.
DR GeneID; 11409371; -.
DR Gramene; AES95924; AES95924; MTR_5g031090.
DR KEGG; mtr:MTR_5g031090; -.
DR eggNOG; ENOG502QTX3; Eukaryota.
DR HOGENOM; CLU_000288_62_2_1; -.
DR OrthoDB; 1114765at2759; -.
DR Proteomes; UP000002051; Chromosome 5.
DR Proteomes; UP000265566; Chromosome 5.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR GO; GO:0009610; P:response to symbiotic fungus; IEP:UniProtKB.
DR CDD; cd06899; lectin_legume_LecRK_Arcelin_ConA; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR016363; L-lectin.
DR InterPro; IPR000985; Lectin_LegA_CS.
DR InterPro; IPR019825; Lectin_legB_Mn/Ca_BS.
DR InterPro; IPR001220; Legume_lectin_dom.
DR Pfam; PF00139; Lectin_legB; 1.
DR PIRSF; PIRSF002690; L-type_lectin_plant; 1.
DR SUPFAM; SSF49899; SSF49899; 1.
DR PROSITE; PS00308; LECTIN_LEGUME_ALPHA; 1.
DR PROSITE; PS00307; LECTIN_LEGUME_BETA; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Lectin; Reference proteome; Signal.
FT SIGNAL 1..31
FT /evidence="ECO:0000255"
FT CHAIN 32..275
FT /note="Lectin 8"
FT /id="PRO_5022658042"
FT CARBOHYD 55
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 150
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CONFLICT 95
FT /note="K -> E (in Ref. 3; ABY48145 and 5; AES95924)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 275 AA; 29915 MW; DFF9A07B66F50A67 CRC64;
MANSNPKLLV TQNPFSVFLL TFLLLITNVK SDSFSFNFPK FDTDTKSIII DGDANTTNGV
LQLTKKDQLG NPSPHSFGLS FFLGAIHLSD KQSGKVADFT TEFSFVVNPK GSQLHGDGFT
FFIASLDYEF PEKSSDGGFL GLFDKESAFN TSQNSIVAVE FDSFRNEWDP QIAGNSPHIG
IDINTIRSSA TALWPIDRVP EGSIGKAHIS YNPASKKLTA LVTYLNGPVI EETAVSYTVD
FAAILPEYVL VGFSGATGEL AETHDILSWS FTSNL
