ARF11_CAEEL
ID ARF11_CAEEL Reviewed; 179 AA.
AC Q94231;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 146.
DE RecName: Full=ADP-ribosylation factor 1-like 1;
DE AltName: Full=ADP-ribosylation factor-like protein 6;
DE AltName: Full=ADP-ribosylation factor-related protein 1.1;
GN Name=arf-1.1; Synonyms=arl-6; ORFNames=F45E4.1;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: GTP-binding protein that may be involved in protein
CC trafficking; may modulate vesicle budding and uncoating within the
CC Golgi apparatus. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Arf family.
CC {ECO:0000305}.
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DR EMBL; FO080446; CCD63776.1; -; Genomic_DNA.
DR PIR; T25757; T25757.
DR RefSeq; NP_501242.1; NM_068841.4.
DR AlphaFoldDB; Q94231; -.
DR SMR; Q94231; -.
DR STRING; 6239.F45E4.1; -.
DR EPD; Q94231; -.
DR PaxDb; Q94231; -.
DR PeptideAtlas; Q94231; -.
DR EnsemblMetazoa; F45E4.1.1; F45E4.1.1; WBGene00000190.
DR GeneID; 191609; -.
DR KEGG; cel:CELE_F45E4.1; -.
DR UCSC; C38D4.8; c. elegans.
DR CTD; 191609; -.
DR WormBase; F45E4.1; CE10492; WBGene00000190; arf-1.1.
DR eggNOG; KOG0070; Eukaryota.
DR HOGENOM; CLU_040729_9_3_1; -.
DR InParanoid; Q94231; -.
DR OMA; IECRTLM; -.
DR OrthoDB; 1345301at2759; -.
DR PhylomeDB; Q94231; -.
DR Reactome; R-CEL-1660514; Synthesis of PIPs at the Golgi membrane.
DR Reactome; R-CEL-6807878; COPI-mediated anterograde transport.
DR Reactome; R-CEL-6811434; COPI-dependent Golgi-to-ER retrograde traffic.
DR PRO; PR:Q94231; -.
DR Proteomes; UP000001940; Chromosome IV.
DR Bgee; WBGene00000190; Expressed in pharyngeal muscle cell (C elegans) and 2 other tissues.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005525; F:GTP binding; IBA:GO_Central.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; HEP:WormBase.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR024156; Small_GTPase_ARF.
DR InterPro; IPR006689; Small_GTPase_ARF/SAR.
DR PANTHER; PTHR11711; PTHR11711; 1.
DR Pfam; PF00025; Arf; 1.
DR PRINTS; PR00328; SAR1GTPBP.
DR SMART; SM00178; SAR; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR00231; small_GTP; 1.
DR PROSITE; PS51417; ARF; 1.
PE 3: Inferred from homology;
KW ER-Golgi transport; Golgi apparatus; GTP-binding; Lipoprotein; Myristate;
KW Nucleotide-binding; Protein transport; Reference proteome; Transport.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000255"
FT CHAIN 2..179
FT /note="ADP-ribosylation factor 1-like 1"
FT /id="PRO_0000207409"
FT BINDING 24..31
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 67..71
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 69
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 126..129
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT LIPID 2
FT /note="N-myristoyl glycine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 179 AA; 20247 MW; 220F426331C7338E CRC64;
MGLFFSKISS FMFPNIECRT LMLGLDGAGK TTILYKLKLN ETVNTIPTIG FNVETVTFQK
ITLTVWDVGG QKKIRALWKY YFPNTTTLVF VVDSSDIERI PEAKEELFSL LAEPELADSH
LLVFANKQDM PNARSPAELT QLLDLGSLKN REWFICGTNA HSGQGLYEGL MWVKKQMKT
