LEC_LUFAC
ID LEC_LUFAC Reviewed; 209 AA.
AC C0HJV2;
DT 06-JUL-2016, integrated into UniProtKB/Swiss-Prot.
DT 06-JUL-2016, sequence version 1.
DT 25-MAY-2022, entry version 6.
DE RecName: Full=Lectin {ECO:0000303|PubMed:26597132};
DE AltName: Full=Agglutinin {ECO:0000303|PubMed:26597132};
DE Short=LAA {ECO:0000303|PubMed:26597132};
OS Luffa acutangula (Ridged gourd) (Cucumis acutangulus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Cucurbitales; Cucurbitaceae; Sicyoeae; Luffa.
OX NCBI_TaxID=56866 {ECO:0000303|PubMed:26597132};
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE, FUNCTION, MASS SPECTROMETRY, DIMERIZATION, AND
RP IDENTIFICATION BY MASS SPECTROMETRY.
RC TISSUE=Phloem {ECO:0000303|PubMed:26597132};
RX PubMed=26597132; DOI=10.1002/iub.1451;
RA Kumar G., Mishra P., Anantharam V., Surolia A.;
RT "Luffa acutangula agglutinin: primary structure determination and
RT identification of a tryptophan residue involved in its carbohydrate-binding
RT activity using mass spectrometry.";
RL IUBMB Life 67:943-953(2015).
CC -!- FUNCTION: Binds chito-oligosaccherides. Has hemagglutinating activity
CC towards rabbit erythrocytes. {ECO:0000269|PubMed:26597132}.
CC -!- SUBUNIT: Homodimer; non-covalently linked.
CC {ECO:0000269|PubMed:26597132}.
CC -!- MASS SPECTROMETRY: Mass=23270; Mass_error=2; Method=MALDI;
CC Evidence={ECO:0000269|PubMed:26597132};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; C0HJV2; -.
DR SMR; C0HJV2; -.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR InterPro; IPR025886; PP2-like.
DR Pfam; PF14299; PP2; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Hemagglutinin; Lectin.
FT CHAIN 1..209
FT /note="Lectin"
FT /evidence="ECO:0000269|PubMed:26597132"
FT /id="PRO_0000436785"
FT SITE 102
FT /note="Important for carbohydrate binding"
FT /evidence="ECO:0000269|PubMed:26597132"
FT UNSURE 3
FT /note="L or I"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 9
FT /note="K or Q"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 14
FT /note="L or I"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 17
FT /note="I or L"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 18
FT /note="L or I"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 19
FT /note="K or Q"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 21
FT /note="L or I"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 32
FT /note="I or L"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 33
FT /note="K or Q"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 34
FT /note="L or I"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 37
FT /note="Q or K"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 42
FT /note="I or L"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 44
FT /note="L or I"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 49
FT /note="K or Q"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 55
FT /note="K or Q"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 64
FT /note="L or I"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 69
FT /note="L or I"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 70
FT /note="L or I"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 71
FT /note="I or L"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 75
FT /note="Q or K"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 77
FT /note="K or Q"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 86
FT /note="Q or K"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 92
FT /note="L or I"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 97
FT /note="L or I"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 98
FT /note="I or L"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 103
FT /note="L or I"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 105
FT /note="I or L"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 109
FT /note="I or L"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 114
FT /note="L or I"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 118
FT /note="I or L"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 128
FT /note="L or I"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 137
FT /note="I or L"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 142
FT /note="K or Q"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 143
FT /note="L or I"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 144
FT /note="K or Q"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 151
FT /note="Q or K"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 154
FT /note="Q or K"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 157
FT /note="L or I"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 158
FT /note="Q or K"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 160
FT /note="K or Q"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 168
FT /note="I or L"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 174
FT /note="K or Q"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 175
FT /note="I or L"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 181
FT /note="I or L"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 184
FT /note="I or L"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 188
FT /note="I or L"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 190
FT /note="Q or K"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 192
FT /note="Q or K"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 195
FT /note="K or Q"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 198
FT /note="L or I"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 199
FT /note="L or I"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 201
FT /note="K or Q"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 203
FT /note="L or I"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 205
FT /note="I or L"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 206
FT /note="Q or K"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 208
FT /note="K or Q"
FT /evidence="ECO:0000303|PubMed:26597132"
FT UNSURE 209
FT /note="Q or K"
FT /evidence="ECO:0000303|PubMed:26597132"
SQ SEQUENCE 209 AA; 23720 MW; 4B98502BD14C1F2C CRC64;
GELVGGEVKV GHNLEAILKG LDVDVYSVPS FIKLYDQVTA GIFLNNRTKR YWFDKNAESN
CFMLYARDLL ITWSQDKRYW RWNPFQEHGN TLEVAELIDV CWLNIVGNIE TSVLSPGISY
EAAFEVMLTN SASGWRIPVD VKLKMPDGSE QESQVNLQDK PRGVWFFISV GHFKISVGET
IGNIEFSIVQ HQEAKRGLLV KGLVIQPKQ
