LEC_ONOVI
ID LEC_ONOVI Reviewed; 236 AA.
AC P02874;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 21-JUL-1986, sequence version 1.
DT 25-MAY-2022, entry version 78.
DE RecName: Full=Lectin;
OS Onobrychis viciifolia (Common sainfoin).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Hedysareae; Onobrychis.
OX NCBI_TaxID=3882;
RN [1]
RP PROTEIN SEQUENCE.
RX PubMed=6722125; DOI=10.1021/bi00303a038;
RA Kouchalakos R.N., Bates O.J., Bradshaw R.A., Hapner K.D.;
RT "Lectin from sainfoin (Onobrychis viciifolia scop.). Complete amino acid
RT sequence.";
RL Biochemistry 23:1824-1830(1984).
CC -!- FUNCTION: D-mannose and D-glucose specific lectin.
CC -!- SUBUNIT: Homodimer of noncovalently associated chains.
CC -!- SIMILARITY: Belongs to the leguminous lectin family. {ECO:0000305}.
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DR PIR; A03366; LNOJ.
DR AlphaFoldDB; P02874; -.
DR SMR; P02874; -.
DR iPTMnet; P02874; -.
DR GO; GO:0005537; F:mannose binding; IEA:UniProtKB-KW.
DR CDD; cd06899; lectin_legume_LecRK_Arcelin_ConA; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR016363; L-lectin.
DR InterPro; IPR000985; Lectin_LegA_CS.
DR InterPro; IPR019825; Lectin_legB_Mn/Ca_BS.
DR InterPro; IPR001220; Legume_lectin_dom.
DR Pfam; PF00139; Lectin_legB; 1.
DR PIRSF; PIRSF002690; L-type_lectin_plant; 1.
DR SUPFAM; SSF49899; SSF49899; 1.
DR PROSITE; PS00308; LECTIN_LEGUME_ALPHA; 1.
DR PROSITE; PS00307; LECTIN_LEGUME_BETA; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Glycoprotein; Lectin; Mannose-binding.
FT CHAIN 1..236
FT /note="Lectin"
FT /id="PRO_0000105109"
FT CARBOHYD 118
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000269|PubMed:6722125"
FT VARIANT 49
FT /note="V -> I (in 50% of the molecules)"
SQ SEQUENCE 236 AA; 26499 MW; E52020E8A1FBF0B5 CRC64;
AENTVSFDFS KFLSGQENLI LQGDTVTDDS NRCLVLTREN NGRPVQDSVG RVLYQTPIHL
WDKQIDKEAS FETSFTFFIY RENINRGGDG ITFFLAPTDT QPKSGGGYLG IFKDAESNET
VVAVEFDTFS NRWDPANSHI GINVNSVKSK ITTPWGLKND YFTVTITYDA TRSLSVSSFY
RNKPDDIFTV KASVHLRDAL PQWVRIGLSA ATGDLVEQHR LYSWSFKSVL PLDSST