ID   LEF1_NPVOP              Reviewed;         243 AA.
AC   Q65362; O12552; O12841;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Late expression factor 1;
GN   Name=LEF-1; ORFNames=ORF13;
OS   Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV).
OC   Viruses; Naldaviricetes; Lefavirales; Baculoviridae; Alphabaculovirus.
OX   NCBI_TaxID=262177;
OH   NCBI_TaxID=33414; Orgyia pseudotsugata (Douglas-fir tussock moth).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8249294; DOI=10.1006/viro.1993.1647;
RA   Pearson M.N., Bjornson R.M., Ahrens C.H., Rohrmann G.F.;
RT   "Identification and characterization of a putative origin of DNA
RT   replication in the genome of a baculovirus pathogenic for Orgyia
RT   pseudotsugata.";
RL   Virology 197:715-725(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7886946; DOI=10.1006/viro.1995.1101;
RA   Ahrens C.H., Rohrmann G.F.;
RT   "Identification of essential trans-acting regions required for DNA
RT   replication of the Orgyia pseudotsugata multinucleocapsid nuclear
RT   polyhedrosis virus: lef-1 is an essential replication gene.";
RL   Virology 207:417-428(1995).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=9126251; DOI=10.1006/viro.1997.8448;
RA   Ahrens C.H., Russell R.R., Funk C.J., Evans J., Harwood S., Rohrmann G.F.;
RT   "The sequence of the Orgyia pseudotsugata multinucleocapsid nuclear
RT   polyhedrosis virus genome.";
RL   Virology 229:381-399(1997).
CC   -!- FUNCTION: Required for late and very late gene expression.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the baculoviridae LEF-1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; D17353; BAA04171.1; -; Genomic_DNA.
DR   EMBL; U75930; AAC59012.1; -; Genomic_DNA.
DR   RefSeq; NP_046169.1; NC_001875.2.
DR   GeneID; 912073; -.
DR   KEGG; vg:912073; -.
DR   Proteomes; UP000009248; Genome.
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0003896; F:DNA primase activity; ISS:UniProtKB.
DR   GO; GO:0019079; P:viral genome replication; ISS:UniProtKB.
DR   InterPro; IPR016658; DNA_primase_LEF1.
DR   PIRSF; PIRSF016433; Viral_DNA_prim; 1.
PE   3: Inferred from homology;
KW   Early protein; Transcription; Transcription regulation.
FT   CHAIN           1..243
FT                   /note="Late expression factor 1"
FT                   /id="PRO_0000132817"
SQ   SEQUENCE   243 AA;  27874 MW;  209E1C6D761B9A66 CRC64;
     MAPCKYTPER VQMMWDAIAY NDSRRLAFMT DRPRWVHAHN FFDSAAQLFA YIVKNSISDV
     HVKPLEEGGR EWVIDADFKD CADKAELMLK VNVGATAFML FFEGKEDAVQ RIMFSGNRGF
     HLWLKFCGKF KMDAPKSLRE HWFNVFKQPA KLVSGDIRPG SFADCVRRAV HMYIGDARED
     LVLRYWPDVD RDVFCNANKQ IRAPFSYNYK GGDYSRCLTQ QLQQRIKACS AGCLAGGTPP
     TSK