LEF2_NPVOP
ID LEF2_NPVOP Reviewed; 204 AA.
AC Q65370; O12547; O12836;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=Late expression factor 2;
GN Name=LEF-2; ORFNames=ORF6;
OS Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV).
OC Viruses; Naldaviricetes; Lefavirales; Baculoviridae; Alphabaculovirus.
OX NCBI_TaxID=262177;
OH NCBI_TaxID=33414; Orgyia pseudotsugata (Douglas-fir tussock moth).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=7571435; DOI=10.1006/viro.1995.1523;
RA Ahrens C.H., Rohrmann G.F.;
RT "Replication of Orgyia pseudotsugata baculovirus DNA: lef-2 and ie-1 are
RT essential and ie-2, p34, and Op-iap are stimulatory genes.";
RL Virology 212:650-662(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=9126251; DOI=10.1006/viro.1997.8448;
RA Ahrens C.H., Russell R.R., Funk C.J., Evans J., Harwood S., Rohrmann G.F.;
RT "The sequence of the Orgyia pseudotsugata multinucleocapsid nuclear
RT polyhedrosis virus genome.";
RL Virology 229:381-399(1997).
CC -!- FUNCTION: Required for late and very late gene expression. Specifically
CC required for expression from the vp39 and polh promoters (By
CC similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the baculoviridae LEF-2 family. {ECO:0000305}.
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DR EMBL; D50053; BAA08770.1; -; Genomic_DNA.
DR EMBL; U75930; AAC59005.1; -; Genomic_DNA.
DR RefSeq; NP_046162.1; NC_001875.2.
DR GeneID; 912094; -.
DR KEGG; vg:912094; -.
DR Proteomes; UP000009248; Genome.
DR GO; GO:0019079; P:viral genome replication; ISS:UniProtKB.
DR GO; GO:0019083; P:viral transcription; IEA:InterPro.
DR InterPro; IPR004283; Lef-2.
DR Pfam; PF03041; Baculo_LEF-2; 1.
PE 3: Inferred from homology;
KW Transcription; Transcription regulation.
FT CHAIN 1..204
FT /note="Late expression factor 2"
FT /id="PRO_0000132821"
SQ SEQUENCE 204 AA; 22697 MW; 33BDDF8CB1EBC2D1 CRC64;
MERVWNPAAG IDGLKRSETY LVDPHDFVGV LTLSPYTVFE RGLFVRMSGM RLLALLAAPK
PQEPQPAVRR FPQRSRRNVC LKACADGAQS LAKVLAARVS MPPCMSKTMA DLSSAPRGNM
YRKRFEFNCY LANVITCTKC KTACLIGALL HFYRMDAKCV GEVTHLLIKA QDVYKPSNCA
KMKKVTKLCP QASMCKGLNP ICNF