LEF9_NPVAC
ID LEF9_NPVAC Reviewed; 516 AA.
AC P41465;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 23-FEB-2022, entry version 62.
DE RecName: Full=DNA-directed RNA polymerase subunit LEF-9;
GN Name=LEF-9;
OS Autographa californica nuclear polyhedrosis virus (AcMNPV).
OC Viruses; Naldaviricetes; Lefavirales; Baculoviridae; Alphabaculovirus.
OX NCBI_TaxID=46015;
OH NCBI_TaxID=7088; Lepidoptera (butterflies and moths).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C6;
RX PubMed=8030224; DOI=10.1006/viro.1994.1380;
RA Ayres M.D., Howard S.C., Kuzio J., Lopez-Ferber M., Possee R.D.;
RT "The complete DNA sequence of Autographa californica nuclear polyhedrosis
RT virus.";
RL Virology 202:586-605(1994).
RN [2]
RP INTERACTION WITH LEF-8; LEF-9 AND P47, AND FUNCTION.
RX PubMed=9733837; DOI=10.1128/jvi.72.10.7985-7991.1998;
RA Guarino L.A., Xu B., Jin J., Dong W.;
RT "A virus-encoded RNA polymerase purified from baculovirus-infected cells.";
RL J. Virol. 72:7985-7991(1998).
CC -!- FUNCTION: Component of the viral DNA-dependent RNA polymerase which is
CC composed of four equimolar subunits of LEF-4, LEF-8, LEF-9, and p47.
CC Plays an essential role in late and very late gene expression.
CC {ECO:0000269|PubMed:9733837}.
CC -!- SUBUNIT: Interacts with LEF-8, LEF-9, and p47.
CC {ECO:0000269|PubMed:9733837}.
CC -!- SIMILARITY: Belongs to the baculoviridae LEF-9 family. {ECO:0000305}.
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DR EMBL; L22858; AAA66692.1; -; Genomic_DNA.
DR PIR; G72857; G72857.
DR RefSeq; NP_054092.1; NC_001623.1.
DR GeneID; 1403895; -.
DR KEGG; vg:1403895; -.
DR Proteomes; UP000008292; Genome.
DR GO; GO:0039695; P:DNA-templated viral transcription; IDA:UniProtKB.
DR InterPro; IPR007786; LEF-9.
DR Pfam; PF05094; LEF-9; 1.
PE 1: Evidence at protein level;
KW Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..516
FT /note="DNA-directed RNA polymerase subunit LEF-9"
FT /id="PRO_0000132831"
SQ SEQUENCE 516 AA; 59305 MW; B625F9E623FC058F CRC64;
MVRKIYFLTL LYFALCVNTR SCTDVIMFSF LDKTPTEFDL ILDPHKLQNV AFFTNEEFKV
ILKNFITDLK KNQKLNYFNS LIDQLINVYT DASVKNTQPD VLAKIIKSTC VIVTDLPSNV
FLKKLKTNKF TDTINYLILP HFILWDHNFV IFLNKAFNSK HENDLVDISG ALQKIKLTHG
VIKDQLQSKN GYAVQYLYAT FLNTASFYAN VQCLNGVNEI MPPRSSVKRY YGRDVDNVRA
WTTRHPNISQ LSTQVSDVHI NESSTDWNVK VGLGIFPGAN TDCDGDKKII TFLPKPNSLI
DSECLLYGDP RFNFICFDKN RLSFVSQQIY YLYKNIDAME ALFKSTPLVY ALWQKHKHEQ
FAQRLEMLLR DFCLIASSNA SYLLFKQLTQ LIANEEMVCG DEEIFNLGGQ FVDMIKSGAK
GSQNLIKSTQ QYRQTLNTDI ETVSSRATTS LNSYISSHNK VKVCGADIYH NTVVLQSVFI
KNNYVCYKND ERTIMNICAL PSEFLFPEHL LDMFIE