LEG1H_DICDI
ID LEG1H_DICDI Reviewed; 326 AA.
AC Q54KF5;
DT 23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 69.
DE RecName: Full=Protein LEG1 homolog {ECO:0000250|UniProtKB:A5PF61, ECO:0000250|UniProtKB:Q4QRF7};
DE Flags: Precursor;
GN Name=leg1 {ECO:0000250|UniProtKB:A5PF61, ECO:0000250|UniProtKB:Q4QRF7};
GN ORFNames=DDB_G0287367;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
RN [2]
RP DEVELOPMENTAL STAGE [LARGE SCALE ANALYSIS].
RX PubMed=12963116; DOI=10.1016/s0925-4773(03)00136-9;
RA Muramoto T., Suzuki K., Shimizu H., Kohara Y., Kohriki E., Obara S.,
RA Tanaka Y., Urushihara H.;
RT "Construction of a gamete-enriched gene pool and RNAi-mediated functional
RT analysis in Dictyostelium discoideum.";
RL Mech. Dev. 120:965-975(2003).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:A5PF61,
CC ECO:0000250|UniProtKB:Q4QRF7}.
CC -!- DEVELOPMENTAL STAGE: Highly enriched in gametes.
CC {ECO:0000269|PubMed:12963116}.
CC -!- SIMILARITY: Belongs to the LEG1 family. {ECO:0000305}.
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DR EMBL; AAFI02000100; EAL63751.1; -; Genomic_DNA.
DR RefSeq; XP_637268.1; XM_632176.1.
DR AlphaFoldDB; Q54KF5; -.
DR SMR; Q54KF5; -.
DR PaxDb; Q54KF5; -.
DR EnsemblProtists; EAL63751; EAL63751; DDB_G0287367.
DR GeneID; 8626099; -.
DR KEGG; ddi:DDB_G0287367; -.
DR dictyBase; DDB_G0287367; -.
DR eggNOG; ENOG502QVPP; Eukaryota.
DR HOGENOM; CLU_071068_0_0_1; -.
DR InParanoid; Q54KF5; -.
DR PhylomeDB; Q54KF5; -.
DR PRO; PR:Q54KF5; -.
DR Proteomes; UP000002195; Chromosome 5.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR InterPro; IPR008499; Leg1.
DR PANTHER; PTHR18820; PTHR18820; 1.
DR Pfam; PF05612; Leg1; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Reference proteome; Secreted; Signal.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT CHAIN 23..326
FT /note="Protein LEG1 homolog"
FT /id="PRO_0000393096"
FT CARBOHYD 58
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 85
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 165
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 226
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 245
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 326 AA; 37991 MW; B30D1AE448CFA552 CRC64;
MKSNKTIFLI LLFLINFNSI YSFNFKKEIK ISNDKINLPT YNPWIFQDRF NLYSILINST
NIPVFGEDNS NNCLHGLQLQ FEWQNRSGRL EINQGHVNTK SWWGDMNYYL SIIPYLSAMK
MGLVPVVEIV SINDQRFCST YEDCDQEVLN NWDNFFQQII NIRNNGSEGD DQQLLKFMWT
AHIGSIDKAT KLFTDSLLLL PKNELRFGNG WAHFVDVIAT VNFNTNYSTV YHLGQQLPPI
MLNSNDTHPS SIESFTKEQR NVVLTMYEIN DLSSNNLVWN SFMYLLKKMT KNEICRNLIN
NEINIFLNSP VPTIIEILFD ILTNNC
