ID   LEGB4_VICFA             Reviewed;         484 AA.
AC   P05190;
DT   13-AUG-1987, integrated into UniProtKB/Swiss-Prot.
DT   13-AUG-1987, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Legumin type B;
DE   Contains:
DE     RecName: Full=Legumin type B alpha chain;
DE     AltName: Full=Legumin type B acidic chain;
DE   Contains:
DE     RecName: Full=Legumin type B beta chain;
DE     AltName: Full=Legumin type B basic chain;
DE   Flags: Precursor;
GN   Name=LEB4;
OS   Vicia faba (Broad bean) (Faba vulgaris).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; Hologalegina; IRL clade; Fabeae; Vicia.
OX   NCBI_TaxID=3906;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3960730; DOI=10.1093/nar/14.6.2707;
RA   Baeumlein H., Wobus U., Pustell J., Kafatos F.C.;
RT   "The legumin gene family: structure of a B type gene of Vicia faba and a
RT   possible legumin gene specific regulatory element.";
RL   Nucleic Acids Res. 14:2707-2720(1986).
CC   -!- FUNCTION: This protein found in the seeds of many leguminous and non-
CC       leguminous plants is the source of sulfur-containing amino acids in
CC       seed meals.
CC   -!- SUBUNIT: Hexamer; each subunit is composed of an acidic and a basic
CC       chain derived from a single precursor and linked by a disulfide bond.
CC   -!- SIMILARITY: Belongs to the 11S seed storage protein (globulins) family.
CC       {ECO:0000305}.
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DR   EMBL; X03677; CAA27313.1; -; Genomic_DNA.
DR   PIR; A24942; A24942.
DR   AlphaFoldDB; P05190; -.
DR   SMR; P05190; -.
DR   PRIDE; P05190; -.
DR   GO; GO:0045735; F:nutrient reservoir activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.120.10; -; 2.
DR   InterPro; IPR022379; 11S_seedstore_CS.
DR   InterPro; IPR006044; 11S_seedstore_pln.
DR   InterPro; IPR006045; Cupin_1.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   InterPro; IPR011051; RmlC_Cupin_sf.
DR   Pfam; PF00190; Cupin_1; 2.
DR   PRINTS; PR00439; 11SGLOBULIN.
DR   SMART; SM00835; Cupin_1; 2.
DR   SUPFAM; SSF51182; SSF51182; 1.
DR   PROSITE; PS00305; 11S_SEED_STORAGE; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Seed storage protein; Signal; Storage protein.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..303
FT                   /note="Legumin type B alpha chain"
FT                   /id="PRO_0000032078"
FT   CHAIN           304..484
FT                   /note="Legumin type B beta chain"
FT                   /id="PRO_0000032079"
FT   DOMAIN          38..257
FT                   /note="Cupin type-1 1"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          316..463
FT                   /note="Cupin type-1 2"
FT                   /evidence="ECO:0000255"
FT   REGION          109..141
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          196..236
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          275..304
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        111..130
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   DISULFID        33..66
FT                   /evidence="ECO:0000250"
FT   DISULFID        109..310
FT                   /note="Interchain (between alpha and beta chains)"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   484 AA;  54448 MW;  3A40F53F43F3D737 CRC64;
     MSKPFLSLLS LSLLLFTSTC LATSSEFDRL NQCRLDNINA LEPDHRVESE AGLTETWNPN
     HPELRCAGVS LIRRTIDPNG LHLPSYSPSP QLIYIIQGKG VIGLTLPGCP QTYQEPRSSQ
     SRQGSRQQQP DSHQKIRRFR KGDIIAIPSG IPYWTYNNGD EPLVAISLLD TSNIANQLDS
     TPRVFYLVGN PEVEFPETQE EQQERHQQKH SLPVGRRGGQ HQQEEESEEQ KDGNSVLSGF
     SSEFLAHTFN TEEDTAKRLR SPRDKRNQIV RVEGGLRIIN PEGQQEEEEE EEEEKQRSEQ
     GRNGLEETIC SLKIRENIAQ PARADLYNPR AGSISTANSL TLPILRYLRL SAEYVRLYRN
     GIYAPHWNIN ANSLLYVIRG EGRVRIVNSQ GNAVFDNKVT KGQLVVVPQN FVVAEQAGEE
     EGLEYLVFKT NDRAAVSHVQ QVFRATPADV LANAFGLRQR QVTELKLSGN RGPLVHPQSQ
     SQSN