LEGLA_XENLA
ID LEGLA_XENLA Reviewed; 171 AA.
AC Q68FJ4;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 76.
DE RecName: Full=Galectin-related protein A;
DE AltName: Full=Lectin galactoside-binding-like protein A;
GN Name=lgalsl-a; Synonyms=grp-a;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Eye;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Does not bind lactose, and may not bind carbohydrates.
CC {ECO:0000250}.
CC -!- CAUTION: Most of the residues in the galectin domain that have been
CC shown to be critical for carbohydrate-binding in other galectins are
CC not conserved. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC079769; AAH79769.1; -; mRNA.
DR RefSeq; NP_001090244.1; NM_001096775.1.
DR AlphaFoldDB; Q68FJ4; -.
DR SMR; Q68FJ4; -.
DR DNASU; 779149; -.
DR GeneID; 779149; -.
DR KEGG; xla:779149; -.
DR CTD; 779149; -.
DR Xenbase; XB-GENE-6252985; lgalsl.S.
DR OrthoDB; 829777at2759; -.
DR Proteomes; UP000186698; Chromosome 5S.
DR Bgee; 779149; Expressed in zone of skin and 19 other tissues.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR CDD; cd00070; GLECT; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR044156; Galectin-like.
DR InterPro; IPR030651; Galectin-rel.
DR InterPro; IPR001079; Galectin_CRD.
DR PANTHER; PTHR11346; PTHR11346; 1.
DR PANTHER; PTHR11346:SF98; PTHR11346:SF98; 1.
DR Pfam; PF00337; Gal-bind_lectin; 1.
DR SMART; SM00908; Gal-bind_lectin; 1.
DR SMART; SM00276; GLECT; 1.
DR SUPFAM; SSF49899; SSF49899; 1.
DR PROSITE; PS51304; GALECTIN; 1.
PE 2: Evidence at transcript level;
KW Lectin; Reference proteome.
FT CHAIN 1..171
FT /note="Galectin-related protein A"
FT /id="PRO_0000315772"
FT DOMAIN 38..170
FT /note="Galectin"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00639"
SQ SEQUENCE 171 AA; 19184 MW; 6F57F840EE981E55 CRC64;
MARSLVESEA LQMGVRRLSS PLTSPVQAEV YFPRLTVPFC GHIKGGLRPG KKILIMGIVN
LEPKSFDIRL TCGDSEDPAA DIAIELRAEF ADKQFLRNAC VSGKWGEEES AIPYFPFIAD
QPFRVEIHCE HPQFRIIVDG HQLFDFYHRV ESLSAINTIK INGDLQLTKL G