LEGLB_MOUSE
ID LEGLB_MOUSE Reviewed; 165 AA.
AC Q7TPX9;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2003, sequence version 1.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=Galectin-related protein B;
DE AltName: Full=Lectin galactoside-binding-like protein B;
GN Name=Lgalslb; Synonyms=Gm5065, Grpb;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Egg;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: Does not bind lactose, and may not bind carbohydrates.
CC {ECO:0000250}.
CC -!- SUBUNIT: Monomer. {ECO:0000250}.
CC -!- CAUTION: Most of the residues in the galectin domain that have been
CC shown to be critical for carbohydrate-binding in other galectins are
CC not conserved. {ECO:0000305}.
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DR EMBL; BC052838; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; CO806202; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; Q7TPX9; -.
DR SMR; Q7TPX9; -.
DR STRING; 10090.ENSMUSP00000055799; -.
DR PaxDb; Q7TPX9; -.
DR PeptideAtlas; Q7TPX9; -.
DR PRIDE; Q7TPX9; -.
DR ProteomicsDB; 291937; -.
DR Ensembl; ENSMUST00000056639; ENSMUSP00000055799; ENSMUSG00000048398.
DR Ensembl; ENSMUST00000207531; ENSMUSP00000146867; ENSMUSG00000048398.
DR UCSC; uc009faf.1; mouse.
DR MGI; MGI:3643170; Gm5065.
DR VEuPathDB; HostDB:ENSMUSG00000048398; -.
DR eggNOG; KOG3587; Eukaryota.
DR GeneTree; ENSGT00940000155337; -.
DR HOGENOM; CLU_037794_2_1_1; -.
DR InParanoid; Q7TPX9; -.
DR OMA; LFDFHHR; -.
DR PhylomeDB; Q7TPX9; -.
DR TreeFam; TF315551; -.
DR PRO; PR:Q7TPX9; -.
DR Proteomes; UP000000589; Chromosome 7.
DR RNAct; Q7TPX9; protein.
DR Bgee; ENSMUSG00000048398; Expressed in secondary oocyte and 5 other tissues.
DR Genevisible; Q7TPX9; MM.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR CDD; cd00070; GLECT; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR044156; Galectin-like.
DR InterPro; IPR030651; Galectin-rel.
DR InterPro; IPR001079; Galectin_CRD.
DR PANTHER; PTHR11346; PTHR11346; 1.
DR PANTHER; PTHR11346:SF98; PTHR11346:SF98; 1.
DR Pfam; PF00337; Gal-bind_lectin; 1.
DR SMART; SM00908; Gal-bind_lectin; 1.
DR SMART; SM00276; GLECT; 1.
DR SUPFAM; SSF49899; SSF49899; 1.
DR PROSITE; PS51304; GALECTIN; 1.
PE 2: Evidence at transcript level;
KW Lectin; Reference proteome.
FT CHAIN 1..165
FT /note="Galectin-related protein B"
FT /id="PRO_0000315768"
FT DOMAIN 32..161
FT /note="Galectin"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00639"
SQ SEQUENCE 165 AA; 18270 MW; 351DBD4F65B51D26 CRC64;
MAGLGANSDV MVKLDDGHLN NSLRSPVQAG VYFRGHIKGG MRPGKKVLVM GIVDHNPKSF
AISLTCGDSE DPPADVAIEL KVVFTNQQVF RNSCISGESD EENLAFPYFP FVPDQPFRME
IFCQQPCFRV LVDGHHLFDF YHRIQTLSAI DSIKISGDLQ ITKLG