LEGL_DANRE
ID LEGL_DANRE Reviewed; 164 AA.
AC Q1ECW6;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-JUL-2006, sequence version 1.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=Galectin-related protein;
DE AltName: Full=Lectin galactoside-binding-like protein;
GN Name=lgalsl; Synonyms=grp; ORFNames=zgc:136758;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Does not bind lactose, and may not bind carbohydrates.
CC {ECO:0000250}.
CC -!- CAUTION: Most of the residues in the galectin domain that have been
CC shown to be critical for carbohydrate-binding in other galectins are
CC not conserved. {ECO:0000305}.
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DR EMBL; BC117644; AAI17645.1; -; mRNA.
DR RefSeq; NP_001038765.1; NM_001045300.1.
DR AlphaFoldDB; Q1ECW6; -.
DR SMR; Q1ECW6; -.
DR PaxDb; Q1ECW6; -.
DR Ensembl; ENSDART00000077390; ENSDARP00000071857; ENSDARG00000059060.
DR GeneID; 723995; -.
DR KEGG; dre:723995; -.
DR CTD; 723995; -.
DR ZFIN; ZDB-GENE-060616-24; lgalsla.
DR eggNOG; KOG3587; Eukaryota.
DR GeneTree; ENSGT00940000155337; -.
DR HOGENOM; CLU_037794_2_1_1; -.
DR InParanoid; Q1ECW6; -.
DR OMA; LFDFHHR; -.
DR OrthoDB; 829777at2759; -.
DR PhylomeDB; Q1ECW6; -.
DR TreeFam; TF315551; -.
DR PRO; PR:Q1ECW6; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 1.
DR Bgee; ENSDARG00000059060; Expressed in spleen and 19 other tissues.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR CDD; cd00070; GLECT; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR044156; Galectin-like.
DR InterPro; IPR030651; Galectin-rel.
DR InterPro; IPR001079; Galectin_CRD.
DR PANTHER; PTHR11346; PTHR11346; 1.
DR PANTHER; PTHR11346:SF98; PTHR11346:SF98; 1.
DR Pfam; PF00337; Gal-bind_lectin; 1.
DR SMART; SM00908; Gal-bind_lectin; 1.
DR SMART; SM00276; GLECT; 1.
DR SUPFAM; SSF49899; SSF49899; 1.
DR PROSITE; PS51304; GALECTIN; 1.
PE 2: Evidence at transcript level;
KW Lectin; Reference proteome.
FT CHAIN 1..164
FT /note="Galectin-related protein"
FT /id="PRO_0000315771"
FT DOMAIN 36..160
FT /note="Galectin"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00639"
SQ SEQUENCE 164 AA; 18459 MW; DE29C50005E5D536 CRC64;
MAELSAVRQE LRSRNLSSSF GELQSPQRDE QKLAVPFCGG IRGGLRPGKK ITIMGVVSAD
PDSFDISLTC GCADVALDMC VRFEEREILR NACVSDQWGD EERSIPYFPF IAEQPFRVEI
HCEHPRFLVL VDGHQLFDFY HRVMPLNAID TIQISGSLTI TKLN