ID   LEG_HELCR               Reviewed;         105 AA.
AC   P22031;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1991, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=D-galactoside-specific lectin;
DE   AltName: Full=Sea urchin egg lectin;
DE            Short=SUEL;
OS   Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC   Euechinoidea; Echinacea; Camarodonta; Echinidea; Echinometridae;
OC   Heliocidaris.
OX   NCBI_TaxID=1043166;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Egg;
RX   PubMed=2001368; DOI=10.1021/bi00223a014;
RA   Ozeki Y., Matsui T., Suzuki M., Titani K.;
RT   "Amino acid sequence and molecular characterization of a D-galactoside-
RT   specific lectin purified from sea urchin (Anthocidaris crassispina) eggs.";
RL   Biochemistry 30:2391-2394(1991).
CC   -!- FUNCTION: This protein binds D-galactoside. May have an important role
CC       in the activation of eggs (triggered by fertilization), or in their
CC       subsequent differentiation. The dimeric form is essential for
CC       hemagglutination activity.
CC   -!- SUBUNIT: Homodimer; disulfide-linked.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm. Note=Cytoplasmic in unfertilized eggs,
CC       and shifted to the peripheral regions after fertilization.
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DR   PIR; A37961; A37961.
DR   AlphaFoldDB; P22031; -.
DR   SMR; P22031; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.120.740; -; 1.
DR   InterPro; IPR000922; Lectin_gal-bd_dom.
DR   InterPro; IPR043159; Lectin_gal-bd_sf.
DR   Pfam; PF02140; Gal_Lectin; 1.
DR   PROSITE; PS50228; SUEL_LECTIN; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; Direct protein sequencing; Disulfide bond; Lectin.
FT   CHAIN           1..105
FT                   /note="D-galactoside-specific lectin"
FT                   /id="PRO_0000207119"
FT   DOMAIN          13..103
FT                   /note="SUEL-type lectin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00260"
SQ   SEQUENCE   105 AA;  11378 MW;  84563A6F37ACD961 CRC64;
     ELVSEFCLKK ERVCEDSSLT ISCPEGEGIV IYDAIYGRKR GEVCPGLFGA FTKNRKCRSS
     NSQQVVENSC EGKSSCTVLA SNSVFGDPCP GTAKYLAVTY ICSFL