LEKR1_HUMAN
ID LEKR1_HUMAN Reviewed; 132 AA.
AC Q6ZMV7; D3DNK8; S4R3D4;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 29-SEP-2021, sequence version 3.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=Protein LEKR1 {ECO:0000305};
GN Name=LEKR1;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16641997; DOI=10.1038/nature04728;
RA Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J.,
RA Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P.,
RA Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A.,
RA Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L.,
RA Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G.,
RA Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W.,
RA Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M.,
RA Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P.,
RA Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H.,
RA Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J.,
RA Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W.,
RA Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B.,
RA Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O.,
RA Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X.,
RA Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R.,
RA Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.;
RT "The DNA sequence, annotation and analysis of human chromosome 3.";
RL Nature 440:1194-1198(2006).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SEQUENCE CAUTION:
CC Sequence=BAD18618.1; Type=Miscellaneous discrepancy; Evidence={ECO:0000305};
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DR EMBL; AK131473; BAD18618.1; ALT_SEQ; mRNA.
DR EMBL; AC106708; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC092993; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC117392; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471052; EAW78719.1; -; Genomic_DNA.
DR EMBL; CH471052; EAW78722.1; -; Genomic_DNA.
DR EMBL; CH471052; EAW78721.1; -; Genomic_DNA.
DR EMBL; BC041967; -; NOT_ANNOTATED_CDS; mRNA.
DR CCDS; CCDS54660.1; -.
DR RefSeq; NP_001180212.1; NM_001193283.1.
DR RefSeq; XP_005247499.1; XM_005247442.3.
DR AlphaFoldDB; Q6ZMV7; -.
DR SMR; Q6ZMV7; -.
DR IntAct; Q6ZMV7; 2.
DR STRING; 9606.ENSP00000474182; -.
DR iPTMnet; Q6ZMV7; -.
DR PhosphoSitePlus; Q6ZMV7; -.
DR BioMuta; LEKR1; -.
DR DMDM; 296434564; -.
DR EPD; Q6ZMV7; -.
DR MassIVE; Q6ZMV7; -.
DR PaxDb; Q6ZMV7; -.
DR PeptideAtlas; Q6ZMV7; -.
DR PRIDE; Q6ZMV7; -.
DR ProteomicsDB; 67922; -.
DR Antibodypedia; 63392; 21 antibodies from 10 providers.
DR DNASU; 389170; -.
DR Ensembl; ENST00000477399.5; ENSP00000425282.1; ENSG00000197980.14.
DR Ensembl; ENST00000491763.1; ENSP00000474182.1; ENSG00000197980.14.
DR GeneID; 389170; -.
DR KEGG; hsa:389170; -.
DR UCSC; uc003fba.2; human.
DR CTD; 389170; -.
DR GeneCards; LEKR1; -.
DR HGNC; HGNC:33765; LEKR1.
DR MIM; 613536; gene.
DR neXtProt; NX_Q6ZMV7; -.
DR OpenTargets; ENSG00000197980; -.
DR VEuPathDB; HostDB:ENSG00000197980; -.
DR GeneTree; ENSGT00940000162647; -.
DR HOGENOM; CLU_030933_1_0_1; -.
DR InParanoid; Q6ZMV7; -.
DR PhylomeDB; Q6ZMV7; -.
DR TreeFam; TF344195; -.
DR PathwayCommons; Q6ZMV7; -.
DR SignaLink; Q6ZMV7; -.
DR ChiTaRS; LEKR1; human.
DR Pharos; Q6ZMV7; Tdark.
DR PRO; PR:Q6ZMV7; -.
DR Proteomes; UP000005640; Chromosome 3.
DR RNAct; Q6ZMV7; protein.
DR Bgee; ENSG00000197980; Expressed in buccal mucosa cell and 100 other tissues.
DR ExpressionAtlas; Q6ZMV7; baseline and differential.
DR InterPro; IPR038799; LEKR1.
DR PANTHER; PTHR34251; PTHR34251; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Reference proteome.
FT CHAIN 1..132
FT /note="Protein LEKR1"
FT /id="PRO_0000325711"
FT COILED 37..116
FT /evidence="ECO:0000255"
SQ SEQUENCE 132 AA; 16005 MW; 93DA1A4A64508858 CRC64;
MDHHIPMHAL PEEIQKMLPE EKVCKYCGVS YLILHEFKAM EEKVKAMEKE MKFYQGSVDR
EKRLQEKLHS LSQELEQYKI DNKSKTERIY DVGMQLKSQQ NEFQKVKKQL SHLQDELKIK
YRQSYIFRLC FC
