ID   LEMD1_MOUSE             Reviewed;         129 AA.
AC   Q14C37;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=LEM domain-containing protein 1;
GN   Name=Lemd1;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; BC115462; AAI15463.1; -; mRNA.
DR   EMBL; BC115463; AAI15464.1; -; mRNA.
DR   CCDS; CCDS35705.1; -.
DR   RefSeq; NP_001028422.2; NM_001033250.4.
DR   RefSeq; XP_006529414.1; XM_006529351.3.
DR   AlphaFoldDB; Q14C37; -.
DR   SMR; Q14C37; -.
DR   STRING; 10090.ENSMUSP00000107976; -.
DR   PhosphoSitePlus; Q14C37; -.
DR   PaxDb; Q14C37; -.
DR   PRIDE; Q14C37; -.
DR   ProteomicsDB; 264937; -.
DR   Antibodypedia; 51435; 38 antibodies from 15 providers.
DR   Ensembl; ENSMUST00000112357; ENSMUSP00000107976; ENSMUSG00000079330.
DR   GeneID; 213409; -.
DR   KEGG; mmu:213409; -.
DR   UCSC; uc007coj.2; mouse.
DR   CTD; 93273; -.
DR   MGI; MGI:1922403; Lemd1.
DR   VEuPathDB; HostDB:ENSMUSG00000079330; -.
DR   eggNOG; ENOG502QWCI; Eukaryota.
DR   GeneTree; ENSGT00940000154098; -.
DR   HOGENOM; CLU_160101_0_0_1; -.
DR   InParanoid; Q14C37; -.
DR   PhylomeDB; Q14C37; -.
DR   TreeFam; TF340652; -.
DR   BioGRID-ORCS; 213409; 3 hits in 72 CRISPR screens.
DR   ChiTaRS; Lemd1; mouse.
DR   PRO; PR:Q14C37; -.
DR   Proteomes; UP000000589; Chromosome 1.
DR   RNAct; Q14C37; protein.
DR   Bgee; ENSMUSG00000079330; Expressed in otolith organ and 80 other tissues.
DR   ExpressionAtlas; Q14C37; baseline and differential.
DR   Genevisible; Q14C37; MM.
DR   Gene3D; 1.10.720.40; -; 1.
DR   InterPro; IPR011015; LEM/LEM-like_dom_sf.
DR   InterPro; IPR003887; LEM_dom.
DR   Pfam; PF03020; LEM; 1.
DR   SMART; SM00540; LEM; 1.
DR   SUPFAM; SSF63451; SSF63451; 1.
DR   PROSITE; PS50954; LEM; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..129
FT                   /note="LEM domain-containing protein 1"
FT                   /id="PRO_0000285248"
FT   DOMAIN          1..45
FT                   /note="LEM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00313"
FT   REGION          45..129
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        70..86
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   129 AA;  14258 MW;  6C6E519FB29641B7 CRC64;
     MVDVKCLSDY ELHKHLMKLG FTPGPILPST RKTYEKKLVQ LLASPPWKPP VMKRPTRPHG
     SEDSDDSEGM LQDQVQGLSG DVSLKKTTLD ATRDPRAAPH TRTPGTTFHA RTLRTAFCGR
     APRTTSHGA