LENG1_MOUSE
ID LENG1_MOUSE Reviewed; 261 AA.
AC Q9DB98;
DT 31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Leukocyte receptor cluster member 1 homolog;
GN Name=Leng1;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Cerebellum;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Czech II; TISSUE=Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
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DR EMBL; AK005095; BAB23814.1; -; mRNA.
DR EMBL; BC023108; AAH23108.1; -; mRNA.
DR CCDS; CCDS20722.1; -.
DR RefSeq; NP_081479.1; NM_027203.3.
DR AlphaFoldDB; Q9DB98; -.
DR SMR; Q9DB98; -.
DR BioGRID; 213661; 2.
DR STRING; 10090.ENSMUSP00000019878; -.
DR iPTMnet; Q9DB98; -.
DR PhosphoSitePlus; Q9DB98; -.
DR EPD; Q9DB98; -.
DR MaxQB; Q9DB98; -.
DR PaxDb; Q9DB98; -.
DR PeptideAtlas; Q9DB98; -.
DR PRIDE; Q9DB98; -.
DR ProteomicsDB; 292251; -.
DR Antibodypedia; 46337; 229 antibodies from 18 providers.
DR DNASU; 69757; -.
DR Ensembl; ENSMUST00000019878; ENSMUSP00000019878; ENSMUSG00000078813.
DR GeneID; 69757; -.
DR KEGG; mmu:69757; -.
DR UCSC; uc009evm.1; mouse.
DR CTD; 79165; -.
DR MGI; MGI:1917007; Leng1.
DR VEuPathDB; HostDB:ENSMUSG00000078813; -.
DR eggNOG; ENOG502RZ97; Eukaryota.
DR GeneTree; ENSGT00510000048131; -.
DR HOGENOM; CLU_058751_2_0_1; -.
DR InParanoid; Q9DB98; -.
DR OMA; DRERPYN; -.
DR OrthoDB; 1518973at2759; -.
DR PhylomeDB; Q9DB98; -.
DR TreeFam; TF317830; -.
DR BioGRID-ORCS; 69757; 16 hits in 71 CRISPR screens.
DR PRO; PR:Q9DB98; -.
DR Proteomes; UP000000589; Chromosome 7.
DR RNAct; Q9DB98; protein.
DR Bgee; ENSMUSG00000078813; Expressed in saccule of membranous labyrinth and 232 other tissues.
DR Genevisible; Q9DB98; MM.
DR InterPro; IPR019339; CIR_N_dom.
DR InterPro; IPR039875; LENG1-like.
DR PANTHER; PTHR22093; PTHR22093; 1.
DR Pfam; PF10197; Cir_N; 1.
DR SMART; SM01083; Cir_N; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Phosphoprotein; Reference proteome.
FT CHAIN 1..261
FT /note="Leukocyte receptor cluster member 1 homolog"
FT /id="PRO_0000254628"
FT REGION 1..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 16..46
FT /evidence="ECO:0000255"
FT COILED 192..222
FT /evidence="ECO:0000255"
FT COMPBIAS 8..60
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..110
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..211
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 59
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q96BZ8"
FT MOD_RES 242
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q96BZ8"
SQ SEQUENCE 261 AA; 30469 MW; 188BFA26EC4F7B74 CRC64;
MNILPKKSWH VRNKDNVARV RRDEAQAREE EKERERRVLL AQQEARTEFL RKKARQRNSV
PELEAADPGA PSSGPVDLFR ELLEERKGVP RGNKEHEEEK RREKERQEKA LGILTYLGQS
AAEAQTQPPW YQLPPGQKDC CPPGPSPDEK IKNRLDPLKE MQKHLAKKRH SSESRPSREE
RPQKQRPREP PSLEKLRAER LQREAAERAR AEALLARVQG QVSQQGQVEA EETDERRRRY
NSQFNPQLAR RPRQQNPTPA H
