ID   LENG8_DANRE             Reviewed;         839 AA.
AC   A4QNR8;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Leukocyte receptor cluster member 8 homolog;
GN   Name=leng8; ORFNames=zgc:158262;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC139488; AAI39489.1; -; mRNA.
DR   RefSeq; NP_001082988.1; NM_001089519.1.
DR   RefSeq; XP_009290356.1; XM_009292081.2.
DR   AlphaFoldDB; A4QNR8; -.
DR   SMR; A4QNR8; -.
DR   STRING; 7955.ENSDARP00000101993; -.
DR   PaxDb; A4QNR8; -.
DR   PeptideAtlas; A4QNR8; -.
DR   Ensembl; ENSDART00000113345; ENSDARP00000101993; ENSDARG00000076805.
DR   GeneID; 100037367; -.
DR   KEGG; dre:100037367; -.
DR   CTD; 114823; -.
DR   ZFIN; ZDB-GENE-070410-6; leng8.
DR   eggNOG; KOG1861; Eukaryota.
DR   GeneTree; ENSGT00390000008006; -.
DR   HOGENOM; CLU_014160_1_0_1; -.
DR   InParanoid; A4QNR8; -.
DR   OMA; PHFYSNQ; -.
DR   OrthoDB; 1503267at2759; -.
DR   PhylomeDB; A4QNR8; -.
DR   TreeFam; TF312927; -.
DR   PRO; PR:A4QNR8; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 16.
DR   Bgee; ENSDARG00000076805; Expressed in brain and 19 other tissues.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   InterPro; IPR000717; PCI_dom.
DR   InterPro; IPR045107; SAC3/GANP/THP3.
DR   InterPro; IPR005062; SAC3/GANP/THP3_conserved.
DR   PANTHER; PTHR12436; PTHR12436; 1.
DR   Pfam; PF03399; SAC3_GANP; 1.
DR   PROSITE; PS50250; PCI; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..839
FT                   /note="Leukocyte receptor cluster member 8 homolog"
FT                   /id="PRO_0000306393"
FT   DOMAIN          675..839
FT                   /note="PCI"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01185"
FT   REGION          1..75
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          106..262
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          287..332
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          400..553
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..25
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        39..75
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        119..141
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        142..193
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        194..210
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        305..331
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        425..447
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        467..482
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        488..553
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   839 AA;  92802 MW;  493651AF7757B9F8 CRC64;
     MAANAAQQAP TQNWPYGNNS SGEGPVHENP EWEKARQALA SISKSQNSTK PSTNQTTQQA
     GQYQAAVTDS SAMQQQQYYQ QWYQQNQQQY AGYPYPYNYY YPMPPYGGPY PPGQYGVPGG
     YQTPTTPTGQ APSMPTMEDQ SSNYPPQPPP PATPQPPPQS PTSSDQPPPP PPPPIPPQPN
     AQYPRPPSQT PYSPNGVLPY SPTDSNPMMR GYNPGQIRPG YQGYQTPVYQ PHQQQAPAPG
     LYGGAGRVDA KKPNNSNMNK GGQQLWQRMK QAPGTGAVKF NIPKRPYVMS NQNFPPGEQG
     PGLAPPTATN PSSGSTSATS SASTGGAQTR PQDWPQAMKE YVQRCFTACE SEEDKDRTEK
     MLKDLLQSRL QDGSAYTIDW NREPLPDLKP KQSRWEVMPQ LSQENSIGRG GATRGRGGAR
     LGNYRNVFSQ RSPSSSSSGS SRSSSRSPSP HSRHRDRSRH HRSDSGSQSD GSMSSDLRLS
     LTRRQQKGGR GRGAERERGR GAAGERGRGR GKANRGRRNM EDLASGVGKK RKGGNAGLDF
     HDPNREAKKQ SRAARFHTKL RTEPLVLNIN VFDLPNGTQE GLSWDDCPIV GTCQDITKNY
     LRLTCAPDPS TVRPVPVLRK SLIAVKAHWK SNQDYVYACE QMKSIRQDLT VQGVRTDFTV
     EVYETHARIA LEKGDHEEFN QCQTQLKALY KDCPSDNVGE FTAYRLIYYI FTKNSGDLTT
     ELVYLTTELR ADPCVAHALE LRTAWALGNF HRFFRLYQKA PRMAAYLIDK FVERERNIAL
     RAILKSFRPS VSVEYVQSSL AFPDLDTCLA FLTGLGISFT PSDPSKIDCK VSSASLTTS