ID   ARFC_MYCBO              Reviewed;         175 AA.
AC   P64758; A0A1R3XXR0; Q10559; X2BGG0;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Uncharacterized membrane protein ArfC;
GN   Name=arfC; OrderedLocusNames=BQ2027_MB0925;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- FUNCTION: Required for wild-type expression of ArfA and ammonia
CC       secretion. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ArfC membrane protein family. {ECO:0000305}.
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DR   EMBL; LT708304; SIT99523.1; -; Genomic_DNA.
DR   RefSeq; NP_854582.1; NC_002945.3.
DR   RefSeq; WP_003404688.1; NC_002945.4.
DR   AlphaFoldDB; P64758; -.
DR   SMR; P64758; -.
DR   EnsemblBacteria; SIT99523; SIT99523; BQ2027_MB0925.
DR   PATRIC; fig|233413.5.peg.1006; -.
DR   OMA; PEDECYE; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..175
FT                   /note="Uncharacterized membrane protein ArfC"
FT                   /id="PRO_0000103742"
FT   TRANSMEM        4..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          36..93
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   175 AA;  18909 MW;  AD7024B10E5E1704 CRC64;
     MEHVHWWLAG LAFTLGMVLT STLMVRPVEH QVLVKKSVRG SSAKSKPPTA RKPAVKSGTK
     REESPTAKTK VATESAAEQI PVAGEPAAEP IPVAGEPAAR IPVVPYAPYG PGSARAGADG
     SGPQGWLVKG RSDTRLYYTP EDPTYDPTVA QVWFQDEESA ARAFFTPWRK STRRT