ID   ARFC_MYCTO              Reviewed;         175 AA.
AC   P9WJG4; L0T6R9; P64757; Q10559;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 36.
DE   RecName: Full=Uncharacterized membrane protein ArfC;
GN   Name=arfC; OrderedLocusNames=MT0924;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: Required for wild-type expression of ArfA and ammonia
CC       secretion, not however part of an ammonia transporter. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ArfC membrane protein family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAK45171.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AE000516; AAK45171.1; ALT_INIT; Genomic_DNA.
DR   PIR; B70783; B70783.
DR   RefSeq; WP_003404688.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WJG4; -.
DR   SMR; P9WJG4; -.
DR   EnsemblBacteria; AAK45171; AAK45171; MT0924.
DR   KEGG; mtc:MT0924; -.
DR   PATRIC; fig|83331.31.peg.993; -.
DR   HOGENOM; CLU_1523548_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..175
FT                   /note="Uncharacterized membrane protein ArfC"
FT                   /id="PRO_0000427834"
FT   TRANSMEM        4..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          36..93
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   175 AA;  18909 MW;  AD7024B10E5E1704 CRC64;
     MEHVHWWLAG LAFTLGMVLT STLMVRPVEH QVLVKKSVRG SSAKSKPPTA RKPAVKSGTK
     REESPTAKTK VATESAAEQI PVAGEPAAEP IPVAGEPAAR IPVVPYAPYG PGSARAGADG
     SGPQGWLVKG RSDTRLYYTP EDPTYDPTVA QVWFQDEESA ARAFFTPWRK STRRT