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LET6_SOLLC
ID   LET6_SOLLC              Reviewed;         355 AA.
AC   O22299;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Homeobox protein knotted-1-like LET6;
GN   Name=LET6;
OS   Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC   Solanum subgen. Lycopersicon.
OX   NCBI_TaxID=4081;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. VFNT Cherry;
RX   PubMed=9484482; DOI=10.1023/a:1005925508579;
RA   Janssen B.-J., Williams A., Chen J.J., Mathern J., Hake S., Sinha N.;
RT   "Isolation and characterization of two knotted-like homeobox genes from
RT   tomato.";
RL   Plant Mol. Biol. 36:417-425(1998).
CC   -!- FUNCTION: May have a role to play in formative events in ovule and
CC       embryo morphogenesis. Probably binds to the DNA sequence 5'-TGAC-3'.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Expressed in developing lateral organs and
CC       developing ovaries in flowers.
CC   -!- SIMILARITY: Belongs to the TALE/KNOX homeobox family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00559}.
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DR   EMBL; AF000141; AAC49917.1; -; mRNA.
DR   PIR; T04317; T04317.
DR   AlphaFoldDB; O22299; -.
DR   SMR; O22299; -.
DR   STRING; 4081.Solyc02g081120.2.1; -.
DR   PaxDb; O22299; -.
DR   PRIDE; O22299; -.
DR   eggNOG; KOG0773; Eukaryota.
DR   InParanoid; O22299; -.
DR   Proteomes; UP000004994; Unplaced.
DR   ExpressionAtlas; O22299; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR005539; ELK_dom.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR008422; Homeobox_KN_domain.
DR   InterPro; IPR005540; KNOX1.
DR   InterPro; IPR005541; KNOX2.
DR   Pfam; PF03789; ELK; 1.
DR   Pfam; PF05920; Homeobox_KN; 1.
DR   Pfam; PF03790; KNOX1; 1.
DR   Pfam; PF03791; KNOX2; 1.
DR   SMART; SM01188; ELK; 1.
DR   SMART; SM00389; HOX; 1.
DR   SMART; SM01255; KNOX1; 1.
DR   SMART; SM01256; KNOX2; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS51213; ELK; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Homeobox; Nucleus; Reference proteome.
FT   CHAIN           1..355
FT                   /note="Homeobox protein knotted-1-like LET6"
FT                   /id="PRO_0000048973"
FT   DOMAIN          237..257
FT                   /note="ELK"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00559"
FT   DNA_BIND        258..321
FT                   /note="Homeobox; TALE-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          75..96
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   355 AA;  39796 MW;  9E9A1AFD75808C49 CRC64;
     MEGGSSGNTS TSCLMMMGYG DHENNNNNNG NGNGNGNGNV TICAPPMMMM MPPPPPSLTN
     NNNAETSNNN ILFLPFMDNN NNNNPQEDNN SSSSSIKSKI MAHPHYHRLL TAYLNCQKIG
     APPEVVARLE EICATSATMG RSSSSSGGGI IGEDPALDQF MEAYCEMLTK YEQELSKPFK
     EAMVFLSRIE CQFKALTLAP NSSHESALGE AMDRNGSSDE EVDVNNSFID PQAEDRELKG
     QLLRKYSGYL GSLKQEFMKK RKKGKLPKEA RQQLVDWWLR HIKWPYPSES QKLALAESTG
     LDQKQINNWF INQRKRHWKP SEDMQFVVMD AAHPHYYMDN VLANHFPMDM TPSLL
 
 
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