ID   ARFF_ORYSJ              Reviewed;         908 AA.
AC   Q6H6V4; A0A0P0VF46; B7EI38; Q8S981;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 108.
DE   RecName: Full=Auxin response factor 6;
DE   AltName: Full=OsARF6a;
GN   Name=ARF6; Synonyms=ARF6A; OrderedLocusNames=Os02g0164900, LOC_Os02g06910;
GN   ORFNames=OJ1661_C12.26, OsJ_005343, OSJNBa0023I17.9;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [6]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 22-417.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=11922106; DOI=10.1266/ggs.76.373;
RA   Sato Y., Nishimura A., Ito M., Ashikari M., Hirano H.-Y., Matsuoka M.;
RT   "Auxin response factor family in rice.";
RL   Genes Genet. Syst. 76:373-380(2001).
RN   [7]
RP   PROTEIN SEQUENCE [LARGE SCALE ANALYSIS] OF 94-100, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16758443; DOI=10.1002/pmic.200600043;
RA   Nozu Y., Tsugita A., Kamijo K.;
RT   "Proteomic analysis of rice leaf, stem and root tissues during growth
RT   course.";
RL   Proteomics 6:3665-3670(2006).
RN   [8]
RP   GENE FAMILY, TISSUE SPECIFICITY, AND NOMENCLATURE.
RX   PubMed=17408882; DOI=10.1016/j.gene.2007.01.006;
RA   Wang D., Pei K., Fu Y., Sun Z., Li S., Liu H., Tang K., Han B., Tao Y.;
RT   "Genome-wide analysis of the auxin response factors (ARF) gene family in
RT   rice (Oryza sativa).";
RL   Gene 394:13-24(2007).
CC   -!- FUNCTION: Auxin response factors (ARFs) are transcriptional factors
CC       that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the
CC       auxin-responsive promoter elements (AuxREs).
CC   -!- SUBUNIT: Homodimers and heterodimers. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00326}.
CC   -!- TISSUE SPECIFICITY: Expressed in roots, culms, leaves and young
CC       panicles. {ECO:0000269|PubMed:17408882}.
CC   -!- DOMAIN: Interactions between auxin response factors (ARFs) and Aux/IAA
CC       proteins occur through their C-terminal dimerization domains III and
CC       IV.
CC   -!- SIMILARITY: Belongs to the ARF family. {ECO:0000305}.
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DR   EMBL; AP004093; BAD25169.1; -; Genomic_DNA.
DR   EMBL; AP004863; BAD25545.1; -; Genomic_DNA.
DR   EMBL; AP008208; BAF07907.1; -; Genomic_DNA.
DR   EMBL; AP014958; BAS77143.1; -; Genomic_DNA.
DR   EMBL; CM000139; EAZ21860.1; -; Genomic_DNA.
DR   EMBL; AK070569; BAG92035.1; -; mRNA.
DR   EMBL; AB071294; BAB85914.1; -; mRNA.
DR   RefSeq; XP_015625706.1; XM_015770220.1.
DR   AlphaFoldDB; Q6H6V4; -.
DR   SMR; Q6H6V4; -.
DR   STRING; 4530.OS02T0164900-01; -.
DR   PaxDb; Q6H6V4; -.
DR   PRIDE; Q6H6V4; -.
DR   EnsemblPlants; Os02t0164900-01; Os02t0164900-01; Os02g0164900.
DR   EnsemblPlants; Os02t0164900-02; Os02t0164900-02; Os02g0164900.
DR   GeneID; 4328406; -.
DR   Gramene; Os02t0164900-01; Os02t0164900-01; Os02g0164900.
DR   Gramene; Os02t0164900-02; Os02t0164900-02; Os02g0164900.
DR   KEGG; osa:4328406; -.
DR   eggNOG; ENOG502QSCZ; Eukaryota.
DR   HOGENOM; CLU_002626_1_0_1; -.
DR   InParanoid; Q6H6V4; -.
DR   OMA; DQVKRPP; -.
DR   OrthoDB; 162380at2759; -.
DR   Proteomes; UP000000763; Chromosome 2.
DR   Proteomes; UP000007752; Chromosome 2.
DR   Proteomes; UP000059680; Chromosome 2.
DR   Genevisible; Q6H6V4; OS.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd10017; B3_DNA; 1.
DR   Gene3D; 2.40.330.10; -; 1.
DR   InterPro; IPR010525; ARF_dom.
DR   InterPro; IPR044835; ARF_plant.
DR   InterPro; IPR033389; AUX/IAA_dom.
DR   InterPro; IPR003340; B3_DNA-bd.
DR   InterPro; IPR015300; DNA-bd_pseudobarrel_sf.
DR   InterPro; IPR000270; PB1_dom.
DR   PANTHER; PTHR31384; PTHR31384; 1.
DR   Pfam; PF02309; AUX_IAA; 1.
DR   Pfam; PF06507; Auxin_resp; 1.
DR   Pfam; PF02362; B3; 1.
DR   SMART; SM01019; B3; 1.
DR   SUPFAM; SSF101936; SSF101936; 1.
DR   PROSITE; PS50863; B3; 1.
DR   PROSITE; PS51745; PB1; 1.
PE   1: Evidence at protein level;
KW   Auxin signaling pathway; Direct protein sequencing; DNA-binding; Nucleus;
KW   Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..908
FT                   /note="Auxin response factor 6"
FT                   /id="PRO_0000299260"
FT   DOMAIN          777..861
FT                   /note="PB1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01081"
FT   DNA_BIND        134..236
FT                   /note="TF-B3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00326"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          525..556
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   908 AA;  100847 MW;  581072770ED932C3 CRC64;
     MKLSPSAGGV SDQPPSPPEV AEEQKCLNSE LWHACAGPLV SLPAVGSRVV YFPQGHSEQV
     AASTNKEMES QIPNYPNLPP QLICQLHNVT MHADAETDEV YAQMTLQPLS PQELKDPFLP
     AELGTASKQP TNYFCKTLTA SDTSTHGGFS VPRRAAEKVF PPLDFTQQPP AQELMAKDLH
     GNEWKFRHIF RGQPKRHLLT TGWSVFVSAK RLVAGDSVLF IWNDSNQLLL GIRRANRPQT
     VMPSSVLSSD SMHIGLLAAA AHAASTNSRF TIFYNPRASP SEFVIPLAKY VKAVYHTRIS
     VGMRFRMLFE TEESSVRRYM GTITGISDLD PVRWMNSHWR SVKVGWDEST AGERQPRVSL
     WEIEPLTTFP MYPSPFPLRL KRPWPTGLPS LYGGKEDDLA SSLMWLRDSQ NTGFQSLNFG
     GLGMSPWMQP RLDSSLLGLQ PDMYQTIAAA AALQNTTKQV SPAMLQFQQP QNIVGRSSLL
     SSQILQQAQP QFQQMYHQNI NGNSIQGHSQ PEYLQQPLQH CQSFNEQKPQ LQPQQQQQES
     HQQQPQHQQM QQQKHLSNFQ TVPNALSVFS QLSSTPQSTP STLQTVSPFS QQHNFPDTNI
     SCLSPSNVSS MHDTLRSFPS EAASDLPGVP RITPVPVSDP WSSKRVAVES TITSRPHDIS
     SQIENFDLTP SSIPQNSTLA PLPGRECLVD QDGSSDPQNH FLFGVNIDSQ SLLMQDGIPS
     LHNENSSSTI PYSTSNFLSP SQDDYPLSQT LTTPGCLDES GYVPCSDNAD QVKRPHATFV
     KVYKSGTVGR LLDITRFSSY HELRSEVGRL FGLEGQLEDP LRSGWQLVFV DREDDVLLVG
     DDPWQEFVNS VSCIKILSPQ EVQQMGKPGI ELFSTSARRL GNSCDNYMSR QESRSLSTGI
     ASVGSVEF