ID   ARFH_ORYSJ              Reviewed;         681 AA.
AC   Q6K223; A0A0P0VLW1; B7FA46; Q0DZD6;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Auxin response factor 8;
GN   Name=ARF8; OrderedLocusNames=Os02g0628600, LOC_Os02g41800;
GN   ORFNames=B1469H02.12, OsJ_07601;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RG   The rice full-length cDNA consortium;
RT   "Oryza sativa full length cDNA.";
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [6]
RP   GENE FAMILY, TISSUE SPECIFICITY, AND NOMENCLATURE.
RX   PubMed=17408882; DOI=10.1016/j.gene.2007.01.006;
RA   Wang D., Pei K., Fu Y., Sun Z., Li S., Liu H., Tang K., Han B., Tao Y.;
RT   "Genome-wide analysis of the auxin response factors (ARF) gene family in
RT   rice (Oryza sativa).";
RL   Gene 394:13-24(2007).
CC   -!- FUNCTION: Auxin response factors (ARFs) are transcriptional factors
CC       that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the
CC       auxin-responsive promoter elements (AuxREs).
CC   -!- SUBUNIT: Homodimers and heterodimers. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00326}.
CC   -!- TISSUE SPECIFICITY: Expressed in roots, culms, leaves and young
CC       panicles. {ECO:0000269|PubMed:17408882}.
CC   -!- DOMAIN: Interactions between auxin response factors (ARFs) and Aux/IAA
CC       proteins occur through their C-terminal dimerization domains III and
CC       IV.
CC   -!- SIMILARITY: Belongs to the ARF family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAF09402.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AP006168; BAD23727.1; -; Genomic_DNA.
DR   EMBL; AP008208; BAF09402.2; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014958; BAS79879.1; -; Genomic_DNA.
DR   EMBL; CM000139; EEE57410.1; -; Genomic_DNA.
DR   EMBL; AK243230; BAH01494.1; -; mRNA.
DR   RefSeq; XP_015622752.1; XM_015767266.1.
DR   AlphaFoldDB; Q6K223; -.
DR   SMR; Q6K223; -.
DR   STRING; 4530.OS02T0628600-01; -.
DR   iPTMnet; Q6K223; -.
DR   PaxDb; Q6K223; -.
DR   PRIDE; Q6K223; -.
DR   EnsemblPlants; Os02t0628600-01; Os02t0628600-01; Os02g0628600.
DR   GeneID; 4330045; -.
DR   Gramene; Os02t0628600-01; Os02t0628600-01; Os02g0628600.
DR   KEGG; osa:4330045; -.
DR   eggNOG; ENOG502QQ5I; Eukaryota.
DR   HOGENOM; CLU_002626_3_5_1; -.
DR   InParanoid; Q6K223; -.
DR   OMA; AWNFRHI; -.
DR   OrthoDB; 216379at2759; -.
DR   Proteomes; UP000000763; Chromosome 2.
DR   Proteomes; UP000007752; Chromosome 2.
DR   Proteomes; UP000059680; Chromosome 2.
DR   Genevisible; Q6K223; OS.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd10017; B3_DNA; 1.
DR   Gene3D; 2.40.330.10; -; 1.
DR   InterPro; IPR010525; ARF_dom.
DR   InterPro; IPR044835; ARF_plant.
DR   InterPro; IPR003340; B3_DNA-bd.
DR   InterPro; IPR015300; DNA-bd_pseudobarrel_sf.
DR   InterPro; IPR000270; PB1_dom.
DR   PANTHER; PTHR31384; PTHR31384; 1.
DR   Pfam; PF06507; Auxin_resp; 1.
DR   Pfam; PF02362; B3; 1.
DR   SMART; SM01019; B3; 1.
DR   SUPFAM; SSF101936; SSF101936; 1.
DR   PROSITE; PS50863; B3; 1.
DR   PROSITE; PS51745; PB1; 1.
PE   2: Evidence at transcript level;
KW   Auxin signaling pathway; DNA-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..681
FT                   /note="Auxin response factor 8"
FT                   /id="PRO_0000299262"
FT   DOMAIN          595..675
FT                   /note="PB1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01081"
FT   DNA_BIND        120..222
FT                   /note="TF-B3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00326"
FT   REGION          474..518
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          534..577
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   681 AA;  73843 MW;  C022D081517BF237 CRC64;
     MITFADLAEP APGAERCVDR QLWLACAGGM CTVPPVGAAV YYFPQGHAEH ALGLAAPELS
     AARVPALVPC RVASVRYMAD PDTDEVFARI RLVPLRAAED GDVEEDGAAA GEEHEKPASF
     AKTLTQSDAN NGGGFSVPRY CAETIFPRLD YAADPPVQTV VAKDVHGVAW NFRHIYRGTP
     RRHLLTTGWS TFVNQKKLVA GDSIVFLRGD GGDLHVGIRR AKRGFCGGGG GAEEASLPGW
     DQYGGLMRGN ASPCAAAKGR GKVRAEDLVE AARLANGGQP FEVVYYPRAS TPEFCVRAAA
     VRAAMRVQWC PGMRFKMAFE TEDSSRISWF MGTVASVQVA DPIRWPQSPW RLLQVTWDEP
     DLLQNVKRVS PWLVELVSSM PAINLSSFSP PRKKPRILAY PEFPFEGQLL NPAFPPNPLA
     HGHHHYHHNH PSFFPFPDVS APAGIQGARH AQFGPSLSDL HLTHLQSSLM YPGLRRPDHV
     GPTSIPPPRI STDLTMGSSP PARALSMGAK KPDDAKPPGL MLFGQRILTE RQMSLSGTTS
     PAATGNSSLN WNTEKGASEG SGSGVIQNSP TDNTSSERLQ WFRENSTVSE LGLEPGQCKV
     FIESDTVGRN LDLSSLASFE QLYGRLSEMF CIDSAELRSR VLYRGATGEV RHAGDEPFSE
     FIKLARRLTI LTDAGSDNLG S