ARFJ_ARATH
ID ARFJ_ARATH Reviewed; 693 AA.
AC Q9SKN5; B2CTC0; B2CTC4; B2CTD5; B2CTE0; Q0WQZ3; Q9SQ86;
DT 26-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 145.
DE RecName: Full=Auxin response factor 10;
GN Name=ARF10; OrderedLocusNames=At2g28350; ORFNames=T1B3.13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], DIMERIZATION, AND TISSUE SPECIFICITY.
RC STRAIN=cv. Columbia;
RX PubMed=10476078; DOI=10.1046/j.1365-313x.1999.00538.x;
RA Ulmasov T., Hagen G., Guilfoyle T.J.;
RT "Dimerization and DNA binding of auxin response factors.";
RL Plant J. 19:309-319(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 365-526, AND VARIANTS ASP-411; SER-473
RP AND ASN-475 DEL.
RC STRAIN=cv. Ag-0, cv. An-1, cv. Bay-0, cv. Br-0, cv. C24, cv. Ct-1,
RC cv. Cvi-1, cv. Edi-0, cv. Ei-2, cv. Ga-0, cv. Gy-0, cv. Kas-2, cv. Ll-0,
RC cv. Mrk-0, cv. Ms-0, cv. Mt-0, cv. Nd-1, cv. Nok-3, cv. Oy-0, cv. Sorbo,
RC cv. Wassilewskija, cv. Wei-0, and cv. Wt-5;
RX PubMed=18305205; DOI=10.1104/pp.108.116582;
RA Ehrenreich I.M., Purugganan M.D.;
RT "Sequence variation of microRNAs and their binding sites in Arabidopsis.";
RL Plant Physiol. 146:1974-1982(2008).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 448-693.
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP GENE FAMILY, NOMENCLATURE, AND FUNCTION.
RX PubMed=12036261; DOI=10.1023/a:1015207114117;
RA Hagen G., Guilfoyle T.J.;
RT "Auxin-responsive gene expression: genes, promoters and regulatory
RT factors.";
RL Plant Mol. Biol. 49:373-385(2002).
RN [8]
RP GENE FAMILY.
RX PubMed=18986826; DOI=10.1016/j.tplants.2008.09.006;
RA Swaminathan K., Peterson K., Jack T.;
RT "The plant B3 superfamily.";
RL Trends Plant Sci. 13:647-655(2008).
CC -!- FUNCTION: Auxin response factors (ARFs) are transcriptional factors
CC that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the
CC auxin-responsive promoter elements (AuxREs). Could act as
CC transcriptional activator or repressor. Formation of heterodimers with
CC Aux/IAA proteins may alter their ability to modulate early auxin
CC response genes expression. {ECO:0000269|PubMed:12036261}.
CC -!- SUBUNIT: Homodimers and heterodimers. {ECO:0000250}.
CC -!- INTERACTION:
CC Q9SKN5; Q8H174: IAA31; NbExp=3; IntAct=EBI-3947482, EBI-3946408;
CC -!- SUBCELLULAR LOCATION: Nucleus.
CC -!- TISSUE SPECIFICITY: Expressed in the whole plant.
CC {ECO:0000269|PubMed:10476078}.
CC -!- DOMAIN: Interactions between auxin response factors (ARFs) and Aux/IAA
CC proteins occur through their C-terminal dimerization domains III and
CC IV.
CC -!- SIMILARITY: Belongs to the ARF family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF04627.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=BAF00456.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AF099735; AAF04627.1; ALT_FRAME; mRNA.
DR EMBL; AC006283; AAD20695.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08110.1; -; Genomic_DNA.
DR EMBL; AF325073; AAK17141.1; -; mRNA.
DR EMBL; AF336919; AAG54000.1; -; mRNA.
DR EMBL; EU550097; ACB30883.1; -; Genomic_DNA.
DR EMBL; EU550098; ACB30884.1; -; Genomic_DNA.
DR EMBL; EU550099; ACB30885.1; -; Genomic_DNA.
DR EMBL; EU550100; ACB30886.1; -; Genomic_DNA.
DR EMBL; EU550101; ACB30887.1; -; Genomic_DNA.
DR EMBL; EU550102; ACB30888.1; -; Genomic_DNA.
DR EMBL; EU550103; ACB30889.1; -; Genomic_DNA.
DR EMBL; EU550104; ACB30890.1; -; Genomic_DNA.
DR EMBL; EU550105; ACB30891.1; -; Genomic_DNA.
DR EMBL; EU550106; ACB30892.1; -; Genomic_DNA.
DR EMBL; EU550107; ACB30893.1; -; Genomic_DNA.
DR EMBL; EU550108; ACB30894.1; -; Genomic_DNA.
DR EMBL; EU550109; ACB30895.1; -; Genomic_DNA.
DR EMBL; EU550110; ACB30896.1; -; Genomic_DNA.
DR EMBL; EU550111; ACB30897.1; -; Genomic_DNA.
DR EMBL; EU550112; ACB30898.1; -; Genomic_DNA.
DR EMBL; EU550113; ACB30899.1; -; Genomic_DNA.
DR EMBL; EU550114; ACB30900.1; -; Genomic_DNA.
DR EMBL; EU550115; ACB30901.1; -; Genomic_DNA.
DR EMBL; EU550116; ACB30902.1; -; Genomic_DNA.
DR EMBL; EU550117; ACB30903.1; -; Genomic_DNA.
DR EMBL; EU550118; ACB30904.1; -; Genomic_DNA.
DR EMBL; EU550119; ACB30905.1; -; Genomic_DNA.
DR EMBL; AK228534; BAF00456.1; ALT_INIT; mRNA.
DR PIR; G84683; G84683.
DR RefSeq; NP_180402.1; NM_128394.5.
DR AlphaFoldDB; Q9SKN5; -.
DR SMR; Q9SKN5; -.
DR BioGRID; 2732; 10.
DR IntAct; Q9SKN5; 15.
DR STRING; 3702.AT2G28350.1; -.
DR PaxDb; Q9SKN5; -.
DR PRIDE; Q9SKN5; -.
DR ProteomicsDB; 224558; -.
DR EnsemblPlants; AT2G28350.1; AT2G28350.1; AT2G28350.
DR GeneID; 817382; -.
DR Gramene; AT2G28350.1; AT2G28350.1; AT2G28350.
DR KEGG; ath:AT2G28350; -.
DR Araport; AT2G28350; -.
DR TAIR; locus:2057517; AT2G28350.
DR eggNOG; ENOG502QQ5I; Eukaryota.
DR HOGENOM; CLU_002626_3_5_1; -.
DR InParanoid; Q9SKN5; -.
DR OrthoDB; 216379at2759; -.
DR PhylomeDB; Q9SKN5; -.
DR PRO; PR:Q9SKN5; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SKN5; baseline and differential.
DR Genevisible; Q9SKN5; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0035198; F:miRNA binding; ISS:TAIR.
DR GO; GO:0009738; P:abscisic acid-activated signaling pathway; IMP:TAIR.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IMP:TAIR.
DR GO; GO:0051301; P:cell division; IGI:TAIR.
DR GO; GO:0048589; P:developmental growth; IMP:TAIR.
DR GO; GO:0010154; P:fruit development; IMP:TAIR.
DR GO; GO:0048366; P:leaf development; IMP:TAIR.
DR GO; GO:0007389; P:pattern specification process; IDA:TAIR.
DR GO; GO:0048441; P:petal development; IMP:TAIR.
DR GO; GO:0031540; P:regulation of anthocyanin biosynthetic process; IMP:TAIR.
DR GO; GO:0009743; P:response to carbohydrate; IMP:TAIR.
DR GO; GO:0048829; P:root cap development; IMP:TAIR.
DR GO; GO:0048442; P:sepal development; IMP:TAIR.
DR CDD; cd10017; B3_DNA; 1.
DR Gene3D; 2.40.330.10; -; 1.
DR InterPro; IPR010525; ARF_dom.
DR InterPro; IPR044835; ARF_plant.
DR InterPro; IPR003340; B3_DNA-bd.
DR InterPro; IPR015300; DNA-bd_pseudobarrel_sf.
DR InterPro; IPR000270; PB1_dom.
DR PANTHER; PTHR31384; PTHR31384; 1.
DR Pfam; PF06507; Auxin_resp; 1.
DR Pfam; PF02362; B3; 1.
DR SMART; SM01019; B3; 1.
DR SUPFAM; SSF101936; SSF101936; 1.
DR PROSITE; PS50863; B3; 1.
DR PROSITE; PS51745; PB1; 1.
PE 1: Evidence at protein level;
KW Auxin signaling pathway; DNA-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..693
FT /note="Auxin response factor 10"
FT /id="PRO_0000111514"
FT DOMAIN 580..668
FT /note="PB1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01081"
FT DNA_BIND 115..217
FT /note="TF-B3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00326"
FT VARIANT 411
FT /note="H -> D (in strain: cv. Ag-0, cv. Bay-0, cv. Br-0,
FT cv. C24, cv. Ct-1, cv. CVi-0, cv. Edi-0, cv. Ei-2, cv. Ga-
FT 0, cv. Gy-0, cv. Kas-2, cv. Ll-0, cv. Mrk-0, cv. Ms-0, cv.
FT Mt-0, cv. Nd-1, cv. Nok-3, cv. Oy-0, cv. Sorbo, cv.
FT Wassilewskija, cv. Wei-0 and cv. Wt-5)"
FT /evidence="ECO:0000269|PubMed:18305205"
FT VARIANT 473
FT /note="G -> S (in strain: cv. Nd-1)"
FT /evidence="ECO:0000269|PubMed:18305205"
FT VARIANT 475
FT /note="Missing (in strain: cv. Bay-0, cv. Ga-0, cv. Ms-0
FT and cv. Oy-0)"
FT /evidence="ECO:0000269|PubMed:18305205"
FT CONFLICT 156
FT /note="I -> N (in Ref. 1; AAF04627)"
FT /evidence="ECO:0000305"
FT CONFLICT 397
FT /note="R -> W (in Ref. 1; AAF04627)"
FT /evidence="ECO:0000305"
FT CONFLICT 585
FT /note="V -> I (in Ref. 6; BAF00456)"
FT /evidence="ECO:0000305"
FT CONFLICT 604
FT /note="Y -> V (in Ref. 1; AAF04627)"
FT /evidence="ECO:0000305"
FT CONFLICT 620
FT /note="R -> G (in Ref. 6; BAF00456)"
FT /evidence="ECO:0000305"
FT CONFLICT 621
FT /note="S -> P (in Ref. 1; AAF04627)"
FT /evidence="ECO:0000305"
FT CONFLICT 624
FT /note="L -> V (in Ref. 1; AAF04627)"
FT /evidence="ECO:0000305"
FT CONFLICT 628
FT /note="V -> G (in Ref. 1; AAF04627)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 693 AA; 76721 MW; 6D3002534DC6F9E7 CRC64;
MEQEKSLDPQ LWHACAGSMV QIPSLNSTVF YFAQGHTEHA HAPPDFHAPR VPPLILCRVV
SVKFLADAET DEVFAKITLL PLPGNDLDLE NDAVLGLTPP SSDGNGNGKE KPASFAKTLT
QSDANNGGGF SVPRYCAETI FPRLDYSAEP PVQTVIAKDI HGETWKFRHI YRGTPRRHLL
TTGWSTFVNQ KKLIAGDSIV FLRSESGDLC VGIRRAKRGG LGSNAGSDNP YPGFSGFLRD
DESTTTTSKL MMMKRNGNND GNAAATGRVR VEAVAEAVAR AACGQAFEVV YYPRASTPEF
CVKAADVRSA MRIRWCSGMR FKMAFETEDS SRISWFMGTV SAVQVADPIR WPNSPWRLLQ
VAWDEPDLLQ NVKRVSPWLV ELVSNMPTIH LSPFSPRKKI RIPQPFEFPF HGTKFPIFSP
GFANNGGGES MCYLSNDNNN APAGIQGARQ AQQLFGSPSP SLLSDLNLSS YTGNNKLHSP
AMFLSSFNPR HHHYQARDSE NSNNISCSLT MGNPAMVQDK KKSVGSVKTH QFVLFGQPIL
TEQQVMNRKR FLEEEAEAEE EKGLVARGLT WNYSLQGLET GHCKVFMESE DVGRTLDLSV
IGSYQELYRK LAEMFHIEER SDLLTHVVYR DANGVIKRIG DEPFSDFMKA TKRLTIKMDI
GGDNVRKTWI TGIRTGENGI DASTKTGPLS IFA