ID   ARFJ_DICDI              Reviewed;         188 AA.
AC   Q54V47;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=ADP-ribosylation factor J;
GN   Name=arrJ; ORFNames=DDB_G0280621;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: GTP-binding protein that may be involved in protein
CC       trafficking. May modulate vesicle budding and uncoating within the
CC       Golgi apparatus (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the small GTPase superfamily. Arf family.
CC       {ECO:0000305}.
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DR   EMBL; AAFI02000037; EAL67112.1; -; Genomic_DNA.
DR   RefSeq; XP_641084.1; XM_635992.1.
DR   AlphaFoldDB; Q54V47; -.
DR   SMR; Q54V47; -.
DR   STRING; 44689.DDB0229372; -.
DR   PaxDb; Q54V47; -.
DR   EnsemblProtists; EAL67112; EAL67112; DDB_G0280621.
DR   GeneID; 8622644; -.
DR   KEGG; ddi:DDB_G0280621; -.
DR   dictyBase; DDB_G0280621; arrJ.
DR   eggNOG; KOG0070; Eukaryota.
DR   HOGENOM; CLU_040729_9_3_1; -.
DR   InParanoid; Q54V47; -.
DR   OMA; AMREMAN; -.
DR   PhylomeDB; Q54V47; -.
DR   Reactome; R-DDI-1660514; Synthesis of PIPs at the Golgi membrane.
DR   Reactome; R-DDI-5620916; VxPx cargo-targeting to cilium.
DR   Reactome; R-DDI-6807878; COPI-mediated anterograde transport.
DR   Reactome; R-DDI-6811434; COPI-dependent Golgi-to-ER retrograde traffic.
DR   PRO; PR:Q54V47; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005525; F:GTP binding; IBA:GO_Central.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR   GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR024156; Small_GTPase_ARF.
DR   InterPro; IPR006689; Small_GTPase_ARF/SAR.
DR   PANTHER; PTHR11711; PTHR11711; 1.
DR   Pfam; PF00025; Arf; 1.
DR   PRINTS; PR00328; SAR1GTPBP.
DR   SMART; SM00178; SAR; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51417; ARF; 1.
PE   3: Inferred from homology;
KW   ER-Golgi transport; Golgi apparatus; GTP-binding; Nucleotide-binding;
KW   Protein transport; Reference proteome; Transport.
FT   CHAIN           1..188
FT                   /note="ADP-ribosylation factor J"
FT                   /id="PRO_0000328146"
FT   BINDING         34..40
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         75..79
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         134..137
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   188 AA;  21394 MW;  BE19D6A5A4B4C50C CRC64;
     MLSELFNSLA SFFSNIFSLF EGKKETRILM IGLDGAGKST LLYKLKLGDV VSTIPTIGFN
     VETIEYKNLS MTVWDVGGQH KIRPLWKHYY HGSNAVIFVV DSTDRERMDE VKEEIDNLLI
     QDELKGTQIL VFANKQDMNN AMNTAEIVNS LDLNSIKDRK WYVQPCSAIR SDGIYEGFDW
     VANSLNNK