ID   ARFL_ORYSI              Reviewed;         816 AA.
AC   Q258Y5; A2XYU3;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   18-APR-2006, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Auxin response factor 12;
DE   AltName: Full=OsARF8;
GN   Name=ARF12; Synonyms=ARF8; ORFNames=H0624F09.13, OsI_017236;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Guang-Lu-Ai No.4;
RX   PubMed=12447439; DOI=10.1038/nature01183;
RA   Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA   Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA   Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA   Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA   Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA   Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA   Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA   Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA   Li J., Hong G., Xue Y., Han B.;
RT   "Sequence and analysis of rice chromosome 4.";
RL   Nature 420:316-320(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=17408882; DOI=10.1016/j.gene.2007.01.006;
RA   Wang D., Pei K., Fu Y., Sun Z., Li S., Liu H., Tang K., Han B., Tao Y.;
RT   "Genome-wide analysis of the auxin response factors (ARF) gene family in
RT   rice (Oryza sativa).";
RL   Gene 394:13-24(2007).
CC   -!- FUNCTION: Auxin response factors (ARFs) are transcriptional factors
CC       that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the
CC       auxin-responsive promoter elements (AuxREs).
CC   -!- SUBUNIT: Homodimers and heterodimers. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00326}.
CC   -!- DOMAIN: Interactions between auxin response factors (ARFs) and Aux/IAA
CC       proteins occur through their C-terminal dimerization domains III and
CC       IV.
CC   -!- SIMILARITY: Belongs to the ARF family. {ECO:0000305}.
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DR   EMBL; AL732356; CAH67705.1; -; Genomic_DNA.
DR   EMBL; CM000129; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; Q258Y5; -.
DR   SMR; Q258Y5; -.
DR   STRING; 39946.Q258Y5; -.
DR   Proteomes; UP000007015; Chromosome 4.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd10017; B3_DNA; 1.
DR   Gene3D; 2.40.330.10; -; 1.
DR   InterPro; IPR010525; ARF_dom.
DR   InterPro; IPR044835; ARF_plant.
DR   InterPro; IPR033389; AUX/IAA_dom.
DR   InterPro; IPR003340; B3_DNA-bd.
DR   InterPro; IPR015300; DNA-bd_pseudobarrel_sf.
DR   InterPro; IPR000270; PB1_dom.
DR   PANTHER; PTHR31384; PTHR31384; 1.
DR   Pfam; PF02309; AUX_IAA; 1.
DR   Pfam; PF06507; Auxin_resp; 1.
DR   Pfam; PF02362; B3; 1.
DR   SMART; SM01019; B3; 1.
DR   SUPFAM; SSF101936; SSF101936; 1.
DR   PROSITE; PS50863; B3; 1.
DR   PROSITE; PS51745; PB1; 1.
PE   3: Inferred from homology;
KW   Auxin signaling pathway; DNA-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..816
FT                   /note="Auxin response factor 12"
FT                   /id="PRO_0000299268"
FT   DOMAIN          717..801
FT                   /note="PB1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01081"
FT   DNA_BIND        135..237
FT                   /note="TF-B3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00326"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          526..565
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        9..23
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        526..550
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   816 AA;  90645 MW;  3E5683AC4FCD313B CRC64;
     MSSSSAASIG PPQPPPPPAP PEEEKKCLNS ELWHACAGPL VCLPTVGTRV VYFPQGHSEQ
     VAASTNKEVE GHIPNYPNLP AQLICQLHDV TMHADVETDE VYAQMTLQPL NPQEQNDAYL
     PAEMGIMSKQ PTNYFCKTLT ASDTSTHGGF SVPRRAAERV FPPLDFTQQP PAQELIARDI
     HDIEWKFRHI FRGQPKRHLL TTGWSVFVSA KRLVAGDSVL FIWNEKNQLL LGIRRASRPQ
     TVMPSSVLSS DSMHIGLLAA AAHAAATNSR FTIFYNPRAS PSEFVIPLSK YIKAVFHTRI
     SVGMRFRMLF ETEESSVRRY MGTITEVSDA DPVRWPSSYW RSVKVGWDES TAGERPPRVS
     LWEIEPLTTF PMYPSLFPLR VKHPWYSGVA SLHDDSNALM WLRGVAGEGG FQSLNFQSPG
     IGSWGQQRLH PSLLSSDHDQ YQAVVAAAAA SQSGGYLKQQ FLHLQQPMQS PQEHCNLNPL
     LQQQILQQAS QQQIINPDAQ NIQTMLSPSA IQQQLQQLQQ MQQVQNDQKQ KIQPDQSYQV
     PTSAVLPSPT SLPSHLREKF GFSDPNANSS SFITSSSSDN MLDSSFLQGS SKAVDLSRFN
     QPVASEQQQQ QAWKQKFMGS QSVSFGGSVL HNSPTSKDGS VENKIGRDVQ NQSLFSPQVD
     SSSLLYNMVP NLTSNVSDGN LSTIPSGSTY LQNAMYGCLD DSSGLLQNTG ENDPATRTFV
     KVYKSGSVGR SLDITRFSNY AELREELGQM FGIKGQLDDP DRSGWQLVFV DRENDVLLLG
     DDPWESFVNS VWYIKILSPE DVHKMGKQGN DPRYLS