ARFN_ARATH
ID ARFN_ARATH Reviewed; 605 AA.
AC Q9LQE8;
DT 26-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2004, sequence version 2.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=Putative auxin response factor 14;
GN Name=ARF14; OrderedLocusNames=At1g35540; ORFNames=F15O4.37;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, NOMENCLATURE, AND FUNCTION.
RX PubMed=12036261; DOI=10.1023/a:1015207114117;
RA Hagen G., Guilfoyle T.J.;
RT "Auxin-responsive gene expression: genes, promoters and regulatory
RT factors.";
RL Plant Mol. Biol. 49:373-385(2002).
RN [4]
RP GENE FAMILY.
RX PubMed=18986826; DOI=10.1016/j.tplants.2008.09.006;
RA Swaminathan K., Peterson K., Jack T.;
RT "The plant B3 superfamily.";
RL Trends Plant Sci. 13:647-655(2008).
CC -!- FUNCTION: Auxin response factors (ARFs) are transcriptional factors
CC that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the
CC auxin-responsive promoter elements (AuxREs). Could act as
CC transcriptional activator or repressor. Formation of heterodimers with
CC Aux/IAA proteins may alter their ability to modulate early auxin
CC response genes expression. {ECO:0000269|PubMed:12036261}.
CC -!- SUBUNIT: Homodimers and heterodimers. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus.
CC -!- DOMAIN: Interactions between auxin response factors (ARFs) and Aux/IAA
CC proteins occur through their C-terminal dimerization domains III and
CC IV.
CC -!- SIMILARITY: Belongs to the ARF family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF79371.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC007887; AAF79371.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE31809.1; -; Genomic_DNA.
DR PIR; G86476; G86476.
DR RefSeq; NP_174786.1; NM_103250.1.
DR AlphaFoldDB; Q9LQE8; -.
DR SMR; Q9LQE8; -.
DR BioGRID; 25682; 3.
DR IntAct; Q9LQE8; 1.
DR STRING; 3702.AT1G35540.1; -.
DR PaxDb; Q9LQE8; -.
DR PRIDE; Q9LQE8; -.
DR EnsemblPlants; AT1G35540.1; AT1G35540.1; AT1G35540.
DR GeneID; 840450; -.
DR Gramene; AT1G35540.1; AT1G35540.1; AT1G35540.
DR KEGG; ath:AT1G35540; -.
DR Araport; AT1G35540; -.
DR TAIR; locus:2014731; AT1G35540.
DR eggNOG; ENOG502QTME; Eukaryota.
DR HOGENOM; CLU_002626_4_4_1; -.
DR OMA; MWAPTIY; -.
DR OrthoDB; 551703at2759; -.
DR PhylomeDB; Q9LQE8; -.
DR PRO; PR:Q9LQE8; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LQE8; baseline.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR CDD; cd10017; B3_DNA; 1.
DR Gene3D; 2.40.330.10; -; 1.
DR InterPro; IPR010525; ARF_dom.
DR InterPro; IPR044835; ARF_plant.
DR InterPro; IPR033389; AUX/IAA_dom.
DR InterPro; IPR003340; B3_DNA-bd.
DR InterPro; IPR015300; DNA-bd_pseudobarrel_sf.
DR InterPro; IPR000270; PB1_dom.
DR PANTHER; PTHR31384; PTHR31384; 1.
DR Pfam; PF02309; AUX_IAA; 1.
DR Pfam; PF06507; Auxin_resp; 1.
DR Pfam; PF02362; B3; 1.
DR SMART; SM01019; B3; 1.
DR SUPFAM; SSF101936; SSF101936; 1.
DR PROSITE; PS50863; B3; 1.
DR PROSITE; PS51745; PB1; 1.
PE 3: Inferred from homology;
KW Auxin signaling pathway; DNA-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..605
FT /note="Putative auxin response factor 14"
FT /id="PRO_0000111518"
FT DOMAIN 510..602
FT /note="PB1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01081"
FT DNA_BIND 126..228
FT /note="TF-B3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00326"
SQ SEQUENCE 605 AA; 68618 MW; 629D3B40BED65A24 CRC64;
MESGNVVNTQ PELSGIIDGS KSYMYEQLWK LCAGPLCDIP KLGEKVYYFP QGHIELVEAS
TREELNELQP ICDFPSKLQC RVIAIQLKVE NNSDETYAEI TLMPDTTQVV IPTQNQNQFR
PLVNSFTKVL TASDTSVHGG FSVPKKHAIE CLPPLDMSQP LPTQEILAID LHGNQWRFRH
IYRGTAQRHL LTIGWNAFTT SKKLVEGDVI VFVRGETGEL RVGIRRAGHQ QGNIPSSIVS
IESMRHGIIA SAKHAFDNQC MFIVVYKPRS SQFIVSYDKF LDVVNNKFNV GSRFTMRFEG
DDFSERRSFG TIIGVSDFSP HWKCSEWRSL EVQWDEFASF PRPNQVSPWD IEHLTPWSNV
SRSSFLKNKR SREVNEIGSS SSHLLPPTLT QGQEIGQQSM ATPMNISLRY RDITEDAMTP
SRLLMSYPVQ PMAKLNYNNV VTPIEENITT NAVASFRLFG VSLATPSVIK DPVEQIGLEI
SRLTQEKKFG QSQILRSPTE IQSKQFSSTR TCTKVQMQGV TIGRAVDLSV LNGYDQLILE
LEKLFDLKGQ LQARNQWEIA FTNNEEDKML VGEDPWPEFC NMVKKIFIYS KEEVKNLKSR
KSLSS
