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ARFO_ARATH
ID   ARFO_ARATH              Reviewed;         593 AA.
AC   Q9LQE3; F4HYE3;
DT   26-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2004, sequence version 2.
DT   03-AUG-2022, entry version 128.
DE   RecName: Full=Putative auxin response factor 15;
GN   Name=ARF15; OrderedLocusNames=At1g35520; ORFNames=F15O4.42;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY, NOMENCLATURE, AND FUNCTION.
RX   PubMed=12036261; DOI=10.1023/a:1015207114117;
RA   Hagen G., Guilfoyle T.J.;
RT   "Auxin-responsive gene expression: genes, promoters and regulatory
RT   factors.";
RL   Plant Mol. Biol. 49:373-385(2002).
RN   [4]
RP   GENE FAMILY.
RX   PubMed=18986826; DOI=10.1016/j.tplants.2008.09.006;
RA   Swaminathan K., Peterson K., Jack T.;
RT   "The plant B3 superfamily.";
RL   Trends Plant Sci. 13:647-655(2008).
CC   -!- FUNCTION: Auxin response factors (ARFs) are transcriptional factors
CC       that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the
CC       auxin-responsive promoter elements (AuxREs). Could act as
CC       transcriptional activator or repressor. Formation of heterodimers with
CC       Aux/IAA proteins may alter their ability to modulate early auxin
CC       response genes expression. {ECO:0000269|PubMed:12036261}.
CC   -!- SUBUNIT: Homodimers and heterodimers. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- DOMAIN: Interactions between auxin response factors (ARFs) and Aux/IAA
CC       proteins occur through their C-terminal dimerization domains III and
CC       IV.
CC   -!- SIMILARITY: Belongs to the ARF family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF79360.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC007887; AAF79360.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002684; AEE31805.2; -; Genomic_DNA.
DR   RefSeq; NP_001319151.1; NM_001333160.1.
DR   AlphaFoldDB; Q9LQE3; -.
DR   SMR; Q9LQE3; -.
DR   BioGRID; 25679; 2.
DR   STRING; 3702.AT1G35520.1; -.
DR   PaxDb; Q9LQE3; -.
DR   PRIDE; Q9LQE3; -.
DR   EnsemblPlants; AT1G35520.1; AT1G35520.1; AT1G35520.
DR   GeneID; 840447; -.
DR   Gramene; AT1G35520.1; AT1G35520.1; AT1G35520.
DR   KEGG; ath:AT1G35520; -.
DR   Araport; AT1G35520; -.
DR   eggNOG; ENOG502QTME; Eukaryota.
DR   HOGENOM; CLU_002626_4_4_1; -.
DR   OMA; VNADNKF; -.
DR   OrthoDB; 551703at2759; -.
DR   PhylomeDB; Q9LQE3; -.
DR   PRO; PR:Q9LQE3; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q9LQE3; differential.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd10017; B3_DNA; 1.
DR   Gene3D; 2.40.330.10; -; 1.
DR   InterPro; IPR010525; ARF_dom.
DR   InterPro; IPR044835; ARF_plant.
DR   InterPro; IPR033389; AUX/IAA_dom.
DR   InterPro; IPR003340; B3_DNA-bd.
DR   InterPro; IPR015300; DNA-bd_pseudobarrel_sf.
DR   InterPro; IPR000270; PB1_dom.
DR   PANTHER; PTHR31384; PTHR31384; 1.
DR   Pfam; PF02309; AUX_IAA; 1.
DR   Pfam; PF06507; Auxin_resp; 1.
DR   Pfam; PF02362; B3; 1.
DR   SMART; SM01019; B3; 1.
DR   SUPFAM; SSF101936; SSF101936; 1.
DR   PROSITE; PS50863; B3; 1.
DR   PROSITE; PS51745; PB1; 1.
PE   3: Inferred from homology;
KW   Auxin signaling pathway; DNA-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..593
FT                   /note="Putative auxin response factor 15"
FT                   /id="PRO_0000111519"
FT   DOMAIN          511..592
FT                   /note="PB1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01081"
FT   DNA_BIND        126..228
FT                   /note="TF-B3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00326"
SQ   SEQUENCE   593 AA;  67421 MW;  8A47C28A808953AC CRC64;
     METGNVVNAQ PELSGIIDRS KSYMYEQLWK LCAGPLCDIP KLGEKVYYFP QGNIELVEAS
     TREELNELQP ICDLPSKLQC RVIAIHLKVE NNSDETYAKI TLMPDTTQVV IPTQNENQFR
     PLVNSFTKVL TASDISANGV FSVPKKHAIE CLPPLDMSQP LPAQELLAID LHGNQWSFRH
     SYRGTPQRHL LTTGWNEFTT SKKLVKGDVI VFVRGETGEL RVGIRRARHQ QGNIPSSIVS
     IDCMRHGVIA SAKHAFDNQC MFIVVYKPRS SQFIVSYDKF LDAVNNKFNV GSRFTMRFEG
     DDLSERRYFG TIIGVSNFSP HWKCSDWRSL EVQWDEFASF LRPNKVSPWE IEHLMPALNV
     PRSSFLKNKR LREVNEFGSS SSHLLPPILT QGQEIGQLSV ASPMNISLLY RETTEDAMNP
     SRLLMSYPVQ PMPKRNYNNQ MVTQIEENIT TKAGTNFRLF GVSLATPPVI KDPIEQIGSD
     ISKLTEGKKF GQSQTLRSPT KIQSKQFSST RTCTKVQMQG VTIGRAVDLS VLNGYDQLIL
     ELEKLFDLKG QLQTRNQWKI IFTGSDEDEM LVGDDPWPEF CNMVKRIYIQ KRR
 
 
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