ARFO_ARATH
ID ARFO_ARATH Reviewed; 593 AA.
AC Q9LQE3; F4HYE3;
DT 26-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2004, sequence version 2.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Putative auxin response factor 15;
GN Name=ARF15; OrderedLocusNames=At1g35520; ORFNames=F15O4.42;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, NOMENCLATURE, AND FUNCTION.
RX PubMed=12036261; DOI=10.1023/a:1015207114117;
RA Hagen G., Guilfoyle T.J.;
RT "Auxin-responsive gene expression: genes, promoters and regulatory
RT factors.";
RL Plant Mol. Biol. 49:373-385(2002).
RN [4]
RP GENE FAMILY.
RX PubMed=18986826; DOI=10.1016/j.tplants.2008.09.006;
RA Swaminathan K., Peterson K., Jack T.;
RT "The plant B3 superfamily.";
RL Trends Plant Sci. 13:647-655(2008).
CC -!- FUNCTION: Auxin response factors (ARFs) are transcriptional factors
CC that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the
CC auxin-responsive promoter elements (AuxREs). Could act as
CC transcriptional activator or repressor. Formation of heterodimers with
CC Aux/IAA proteins may alter their ability to modulate early auxin
CC response genes expression. {ECO:0000269|PubMed:12036261}.
CC -!- SUBUNIT: Homodimers and heterodimers. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus.
CC -!- DOMAIN: Interactions between auxin response factors (ARFs) and Aux/IAA
CC proteins occur through their C-terminal dimerization domains III and
CC IV.
CC -!- SIMILARITY: Belongs to the ARF family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF79360.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC007887; AAF79360.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE31805.2; -; Genomic_DNA.
DR RefSeq; NP_001319151.1; NM_001333160.1.
DR AlphaFoldDB; Q9LQE3; -.
DR SMR; Q9LQE3; -.
DR BioGRID; 25679; 2.
DR STRING; 3702.AT1G35520.1; -.
DR PaxDb; Q9LQE3; -.
DR PRIDE; Q9LQE3; -.
DR EnsemblPlants; AT1G35520.1; AT1G35520.1; AT1G35520.
DR GeneID; 840447; -.
DR Gramene; AT1G35520.1; AT1G35520.1; AT1G35520.
DR KEGG; ath:AT1G35520; -.
DR Araport; AT1G35520; -.
DR eggNOG; ENOG502QTME; Eukaryota.
DR HOGENOM; CLU_002626_4_4_1; -.
DR OMA; VNADNKF; -.
DR OrthoDB; 551703at2759; -.
DR PhylomeDB; Q9LQE3; -.
DR PRO; PR:Q9LQE3; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LQE3; differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd10017; B3_DNA; 1.
DR Gene3D; 2.40.330.10; -; 1.
DR InterPro; IPR010525; ARF_dom.
DR InterPro; IPR044835; ARF_plant.
DR InterPro; IPR033389; AUX/IAA_dom.
DR InterPro; IPR003340; B3_DNA-bd.
DR InterPro; IPR015300; DNA-bd_pseudobarrel_sf.
DR InterPro; IPR000270; PB1_dom.
DR PANTHER; PTHR31384; PTHR31384; 1.
DR Pfam; PF02309; AUX_IAA; 1.
DR Pfam; PF06507; Auxin_resp; 1.
DR Pfam; PF02362; B3; 1.
DR SMART; SM01019; B3; 1.
DR SUPFAM; SSF101936; SSF101936; 1.
DR PROSITE; PS50863; B3; 1.
DR PROSITE; PS51745; PB1; 1.
PE 3: Inferred from homology;
KW Auxin signaling pathway; DNA-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..593
FT /note="Putative auxin response factor 15"
FT /id="PRO_0000111519"
FT DOMAIN 511..592
FT /note="PB1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01081"
FT DNA_BIND 126..228
FT /note="TF-B3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00326"
SQ SEQUENCE 593 AA; 67421 MW; 8A47C28A808953AC CRC64;
METGNVVNAQ PELSGIIDRS KSYMYEQLWK LCAGPLCDIP KLGEKVYYFP QGNIELVEAS
TREELNELQP ICDLPSKLQC RVIAIHLKVE NNSDETYAKI TLMPDTTQVV IPTQNENQFR
PLVNSFTKVL TASDISANGV FSVPKKHAIE CLPPLDMSQP LPAQELLAID LHGNQWSFRH
SYRGTPQRHL LTTGWNEFTT SKKLVKGDVI VFVRGETGEL RVGIRRARHQ QGNIPSSIVS
IDCMRHGVIA SAKHAFDNQC MFIVVYKPRS SQFIVSYDKF LDAVNNKFNV GSRFTMRFEG
DDLSERRYFG TIIGVSNFSP HWKCSDWRSL EVQWDEFASF LRPNKVSPWE IEHLMPALNV
PRSSFLKNKR LREVNEFGSS SSHLLPPILT QGQEIGQLSV ASPMNISLLY RETTEDAMNP
SRLLMSYPVQ PMPKRNYNNQ MVTQIEENIT TKAGTNFRLF GVSLATPPVI KDPIEQIGSD
ISKLTEGKKF GQSQTLRSPT KIQSKQFSST RTCTKVQMQG VTIGRAVDLS VLNGYDQLIL
ELEKLFDLKG QLQTRNQWKI IFTGSDEDEM LVGDDPWPEF CNMVKRIYIQ KRR