ID   LEUE_CITK8              Reviewed;         212 AA.
AC   A8AHJ0;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Leucine efflux protein;
GN   Name=leuE; OrderedLocusNames=CKO_01825;
OS   Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Citrobacter.
OX   NCBI_TaxID=290338;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-895 / CDC 4225-83 / SGSC4696;
RG   The Citrobacter koseri Genome Sequencing Project;
RA   McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA   Latreille P., Courtney L., Wang C., Pepin K., Bhonagiri V., Nash W.,
RA   Johnson M., Thiruvilangam P., Wilson R.;
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exporter of leucine. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the Rht family. {ECO:0000305}.
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DR   EMBL; CP000822; ABV12953.1; -; Genomic_DNA.
DR   RefSeq; WP_012132690.1; NC_009792.1.
DR   AlphaFoldDB; A8AHJ0; -.
DR   STRING; 290338.CKO_01825; -.
DR   EnsemblBacteria; ABV12953; ABV12953; CKO_01825.
DR   GeneID; 45135835; -.
DR   KEGG; cko:CKO_01825; -.
DR   HOGENOM; CLU_079569_3_1_6; -.
DR   OMA; AGVWCGD; -.
DR   OrthoDB; 1927576at2; -.
DR   Proteomes; UP000008148; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   InterPro; IPR001123; LeuE-type.
DR   PANTHER; PTHR30086; PTHR30086; 1.
DR   Pfam; PF01810; LysE; 1.
DR   PIRSF; PIRSF006324; LeuE; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..212
FT                   /note="Leucine efflux protein"
FT                   /id="PRO_0000316796"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        72..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        120..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        153..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        188..208
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   212 AA;  23132 MW;  309D9FE7F9BF939E CRC64;
     MFAEYGVLNY WTYLVGAIFI VLVPGPNTIF VLKNSVGRGM KGGYLAASGV FIGDAVLMFL
     AYAGVATLIK TTPVLFNIVR YLGAFYLLYL GAKILYATLK SKGSEVAHDE VPFGAIFKRA
     LILSLTNPKA ILFYVSFFVQ FIDVNAPHAG LSFFILATTL EVVSFFYLSF LIISGAFVTQ
     YIRTKKKLAK VGNSLIGLIF VGFAARLATL QS