ID   LEUE_ENT38              Reviewed;         211 AA.
AC   A4WB82;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Leucine efflux protein;
GN   Name=leuE; OrderedLocusNames=Ent638_2293;
OS   Enterobacter sp. (strain 638).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Enterobacter.
OX   NCBI_TaxID=399742;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=638;
RX   PubMed=20485560; DOI=10.1371/journal.pgen.1000943;
RA   Taghavi S., van der Lelie D., Hoffman A., Zhang Y.B., Walla M.D.,
RA   Vangronsveld J., Newman L., Monchy S.;
RT   "Genome sequence of the plant growth promoting endophytic bacterium
RT   Enterobacter sp. 638.";
RL   PLoS Genet. 6:E1000943-E1000943(2010).
CC   -!- FUNCTION: Exporter of leucine. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the Rht family. {ECO:0000305}.
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DR   EMBL; CP000653; ABP60962.1; -; Genomic_DNA.
DR   RefSeq; WP_012017676.1; NC_009436.1.
DR   AlphaFoldDB; A4WB82; -.
DR   STRING; 399742.Ent638_2293; -.
DR   PRIDE; A4WB82; -.
DR   EnsemblBacteria; ABP60962; ABP60962; Ent638_2293.
DR   KEGG; ent:Ent638_2293; -.
DR   eggNOG; COG1280; Bacteria.
DR   HOGENOM; CLU_079569_3_1_6; -.
DR   OMA; AGVWCGD; -.
DR   OrthoDB; 1927576at2; -.
DR   Proteomes; UP000000230; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   InterPro; IPR001123; LeuE-type.
DR   PANTHER; PTHR30086; PTHR30086; 1.
DR   Pfam; PF01810; LysE; 1.
DR   PIRSF; PIRSF006324; LeuE; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..211
FT                   /note="Leucine efflux protein"
FT                   /id="PRO_0000316797"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        72..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        122..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        153..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        191..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   211 AA;  22953 MW;  B34DBBCFF2ADAE1C CRC64;
     MFAEFGVLNF WTYVVGAFFI VLVPGPNTLF VLKTGIGHGV KKGYLAATGV FIGDAVLMFL
     AWAGVAALIQ TTPVLFNIVR YLGALYLLWL GGKMLWSVIM RKNSAHAGGA EPSSTILKRS
     LVLSLTNPKA ILFYVSFFVQ FIDVSATNTG TSFLILATTL ELISFMYMSF LIFSGAFVTR
     YLKTKKKLAK LGNGLIGLLF VGFAARLASL H