ID   LEUE_SALCH              Reviewed;         212 AA.
AC   Q57Q25;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Leucine efflux protein;
GN   Name=leuE; OrderedLocusNames=SCH_1280;
OS   Salmonella choleraesuis (strain SC-B67).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=321314;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC-B67;
RX   PubMed=15781495; DOI=10.1093/nar/gki297;
RA   Chiu C.-H., Tang P., Chu C., Hu S., Bao Q., Yu J., Chou Y.-Y., Wang H.-S.,
RA   Lee Y.-S.;
RT   "The genome sequence of Salmonella enterica serovar Choleraesuis, a highly
RT   invasive and resistant zoonotic pathogen.";
RL   Nucleic Acids Res. 33:1690-1698(2005).
CC   -!- FUNCTION: Exporter of leucine. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the Rht family. {ECO:0000305}.
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DR   EMBL; AE017220; AAX65186.1; -; Genomic_DNA.
DR   RefSeq; WP_000457190.1; NC_006905.1.
DR   AlphaFoldDB; Q57Q25; -.
DR   EnsemblBacteria; AAX65186; AAX65186; SCH_1280.
DR   KEGG; sec:SCH_1280; -.
DR   HOGENOM; CLU_079569_3_1_6; -.
DR   OMA; AGVWCGD; -.
DR   Proteomes; UP000000538; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   InterPro; IPR001123; LeuE-type.
DR   PANTHER; PTHR30086; PTHR30086; 1.
DR   Pfam; PF01810; LysE; 1.
DR   PIRSF; PIRSF006324; LeuE; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..212
FT                   /note="Leucine efflux protein"
FT                   /id="PRO_0000316806"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        120..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        153..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        188..208
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   212 AA;  22946 MW;  E6A80F6EB92912BB CRC64;
     MFAEYGVLNY WTYLVGAIFI VLVPGPNTLF VLKNSVGRGV KGGYLAACGV FIGDAILMFL
     AYAGVATLIK TTPVLFNIVR YLGAFYLLYL GAKILYATLT SKGRAATETV VPFGAIFKRA
     LILSLTNPKA ILFYVSFFVQ FIDVTAPHTG VSFFILATTL EIVSFCYLSF LILSGAFVTH
     YIGTKKKLAK VGNSLIGLLF VGFAARLATL QS