ID   LEUE_SHIBS              Reviewed;         191 AA.
AC   Q321T8; Q321T6;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 2.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Putative leucine efflux protein;
GN   Name=leuE; OrderedLocusNames=SBO_1292/SBO_1294;
OS   Shigella boydii serotype 4 (strain Sb227).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=300268;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Sb227;
RX   PubMed=16275786; DOI=10.1093/nar/gki954;
RA   Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X., Wang J.,
RA   Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S., Nie H., Peng J.,
RA   Xu J., Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y., Qiang B., Hou Y., Yu J.,
RA   Jin Q.;
RT   "Genome dynamics and diversity of Shigella species, the etiologic agents of
RT   bacillary dysentery.";
RL   Nucleic Acids Res. 33:6445-6458(2005).
CC   -!- FUNCTION: Exporter of leucine. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the Rht family. {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. The gene coding for this
CC       protein is interrupted by a IS1 element between amino acids 114 and
CC       115. The N-terminus is shorter than orthologs. {ECO:0000305}.
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DR   EMBL; CP000036; ABB65920.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP000036; ABB65922.1; ALT_SEQ; Genomic_DNA.
DR   AlphaFoldDB; Q321T8; -.
DR   EnsemblBacteria; ABB65920; ABB65920; SBO_1292.
DR   EnsemblBacteria; ABB65922; ABB65922; SBO_1294.
DR   KEGG; sbo:SBO_1292; -.
DR   KEGG; sbo:SBO_1294; -.
DR   HOGENOM; CLU_079569_5_1_6; -.
DR   Proteomes; UP000007067; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   InterPro; IPR001123; LeuE-type.
DR   PANTHER; PTHR30086; PTHR30086; 1.
DR   Pfam; PF01810; LysE; 1.
DR   PIRSF; PIRSF006324; LeuE; 1.
PE   5: Uncertain;
KW   Amino-acid transport; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..191
FT                   /note="Putative leucine efflux protein"
FT                   /id="PRO_0000316810"
FT   TRANSMEM        28..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        50..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        132..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        167..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   191 AA;  20896 MW;  11FB614DF8237316 CRC64;
     MVPGPNTLFV LKNSVSSGMK GGYLAACGVF IGDAVLMFLA WAGVATLIKT TPILFNIVRY
     LGAFYLLYLE SKILYATLKG KNNEAKSDEP QYGAIFKRAL ILSLTNPKAI LFYVSFFVQF
     IDVNAPHTGI SFFILATTLE LVSFCYLSFL IISGAFVTQY IRTKKKLAKV GNSLIGLMFV
     GFAARLATLQ S