ID   LEXM_RAT                Reviewed;         402 AA.
AC   B1H283;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Lymphocyte expansion molecule;
GN   Name=Lexm {ECO:0000312|RGD:1559493};
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- CAUTION: Was reported to promote CD8+ T cell immunity through effects
CC       on mitochondrial respiration. However, the corresponding article has
CC       been retracted. {ECO:0000250|UniProtKB:A2AVQ5}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CH474008; EDL90470.1; -; Genomic_DNA.
DR   EMBL; BC160900; AAI60900.1; -; mRNA.
DR   RefSeq; NP_001102732.1; NM_001109262.2.
DR   AlphaFoldDB; B1H283; -.
DR   STRING; 10116.ENSRNOP00000047785; -.
DR   PaxDb; B1H283; -.
DR   PRIDE; B1H283; -.
DR   Ensembl; ENSRNOT00000052130; ENSRNOP00000047785; ENSRNOG00000030914.
DR   GeneID; 500516; -.
DR   KEGG; rno:500516; -.
DR   UCSC; RGD:1559493; rat.
DR   CTD; 163747; -.
DR   RGD; 1559493; Lexm.
DR   eggNOG; KOG4087; Eukaryota.
DR   GeneTree; ENSGT00390000015471; -.
DR   HOGENOM; CLU_053450_0_0_1; -.
DR   InParanoid; B1H283; -.
DR   OMA; PFTKGKC; -.
DR   OrthoDB; 826582at2759; -.
DR   PhylomeDB; B1H283; -.
DR   TreeFam; TF329164; -.
DR   PRO; PR:B1H283; -.
DR   Proteomes; UP000002494; Chromosome 5.
DR   Proteomes; UP000234681; Chromosome 5.
DR   Bgee; ENSRNOG00000030914; Expressed in testis and 2 other tissues.
DR   GO; GO:0005739; C:mitochondrion; ISO:RGD.
DR   GO; GO:0097177; F:mitochondrial ribosome binding; ISO:RGD.
DR   GO; GO:0008284; P:positive regulation of cell population proliferation; ISO:RGD.
DR   GO; GO:1903862; P:positive regulation of oxidative phosphorylation; ISO:RGD.
DR   InterPro; IPR033557; LEXM.
DR   PANTHER; PTHR34914; PTHR34914; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..402
FT                   /note="Lymphocyte expansion molecule"
FT                   /id="PRO_0000363882"
SQ   SEQUENCE   402 AA;  45835 MW;  1A6457C43C13D232 CRC64;
     MSTIRKWFKG APFGVQSHRF DVSAVHPNQK KFSTFTEAPY SRHHSVELSH IGPGTYNSKE
     TCFSKKFLEQ KLGAGWARAQ EASRLTQLPH FHFQAIKKER EQQANKRGPG SYNIKDFLTE
     LQKKPQSKRG LLSSGETRFR GLIGNYYPGP GNYGEKGNPY TQLEKNSWNR SHSDGLMCRL
     SSKPPPLSHQ GSGLGPGTYT IKSDIETFVE KSTGTRGPYD IFSGERSSPV PYGHYSVQKK
     KPRELTSFKS FVDELNAPHK KKQGGFSKYP RDPKHPTERI YWTTLSQCPK DVNVAGPGSW
     LPHETEQKHV NRPPFLLASK RSGLKACQML LGTWNPVGVG RYLNTTLMEK IDRRQRYRSL
     FMSEPKRYLH DLNRDKLLQE RITPFTKGKC RPTVDYNSDP TP