LFG4_ARATH
ID LFG4_ARATH Reviewed; 247 AA.
AC Q9SA63;
DT 27-SEP-2017, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=Protein LIFEGUARD 4 {ECO:0000303|PubMed:23888068};
DE Short=AtLFG4 {ECO:0000303|PubMed:23888068};
GN Name=LFG4 {ECO:0000303|PubMed:23888068};
GN OrderedLocusNames=At1g03070 {ECO:0000312|Araport:AT1G03070};
GN ORFNames=F10O3.11 {ECO:0000312|EMBL:AAD25802.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Cheuk R.F., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY.
RX PubMed=19202280; DOI=10.1271/bbb.80752;
RA Yamagami A., Nakazawa M., Matsui M., Tujimoto M., Sakuta M., Asami T.,
RA Nakano T.;
RT "Chemical genetics reveal the novel transmembrane protein BIL4, which
RT mediates plant cell elongation in brassinosteroid signaling.";
RL Biosci. Biotechnol. Biochem. 73:415-421(2009).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=23888068; DOI=10.1093/jxb/ert217;
RA Weis C., Hueckelhoven R., Eichmann R.;
RT "LIFEGUARD proteins support plant colonization by biotrophic powdery mildew
RT fungi.";
RL J. Exp. Bot. 64:3855-3867(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the BI1 family. {ECO:0000305}.
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DR EMBL; AC006550; AAD25802.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE27524.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE27525.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM58047.1; -; Genomic_DNA.
DR EMBL; BT010903; AAR24681.1; -; mRNA.
DR EMBL; AK175449; BAD43212.1; -; mRNA.
DR PIR; E86161; E86161.
DR RefSeq; NP_001184896.1; NM_001197967.2.
DR RefSeq; NP_001320512.1; NM_001331384.1.
DR RefSeq; NP_171806.1; NM_100189.3.
DR AlphaFoldDB; Q9SA63; -.
DR SMR; Q9SA63; -.
DR IntAct; Q9SA63; 18.
DR STRING; 3702.AT1G03070.2; -.
DR PaxDb; Q9SA63; -.
DR PRIDE; Q9SA63; -.
DR ProteomicsDB; 238457; -.
DR EnsemblPlants; AT1G03070.1; AT1G03070.1; AT1G03070.
DR EnsemblPlants; AT1G03070.2; AT1G03070.2; AT1G03070.
DR EnsemblPlants; AT1G03070.3; AT1G03070.3; AT1G03070.
DR GeneID; 839581; -.
DR Gramene; AT1G03070.1; AT1G03070.1; AT1G03070.
DR Gramene; AT1G03070.2; AT1G03070.2; AT1G03070.
DR Gramene; AT1G03070.3; AT1G03070.3; AT1G03070.
DR KEGG; ath:AT1G03070; -.
DR Araport; AT1G03070; -.
DR TAIR; locus:2007509; AT1G03070.
DR eggNOG; KOG2322; Eukaryota.
DR HOGENOM; CLU_058671_0_1_1; -.
DR InParanoid; Q9SA63; -.
DR OMA; YPGDTEM; -.
DR OrthoDB; 1290306at2759; -.
DR PhylomeDB; Q9SA63; -.
DR PRO; PR:Q9SA63; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SA63; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR InterPro; IPR006214; Bax_inhibitor_1-related.
DR PANTHER; PTHR23291; PTHR23291; 1.
DR Pfam; PF01027; Bax1-I; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..247
FT /note="Protein LIFEGUARD 4"
FT /id="PRO_0000441632"
FT TRANSMEM 42..62
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 75..95
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 130..150
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 165..185
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 188..208
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 222..242
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 247 AA; 27882 MW; FA881629E86EA317 CRC64;
MYKWNLPYRK DDVETGREGG ERSLYPTMLE SPELRWGFIR KVYSIIAFQL LATIAVASTV
VFVRPIAVFF ATTSAGLALW IVLIITPLIV MCPLYYYHQK HPVNYLLLGI FTVALAFAVG
LTCAFTSGKV ILEAAILTTV VVLSLTVYTF WAAKKGYDFN FLGPFLFGAL IVLMVFALIQ
IFFPLGRISV MIYGCLAAII FCGYIVYDTD NLIKRYSYDE YIWAAVSLYL DIINLFLALL
TIFRAAE
