LFG5_ARATH
ID LFG5_ARATH Reviewed; 256 AA.
AC Q94A20; O23399; Q940C4;
DT 23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=BI1-like protein;
DE AltName: Full=Protein LIFEGUARD 5 {ECO:0000303|PubMed:23888068};
DE Short=AtLFG5 {ECO:0000303|PubMed:23888068};
GN Name=LFG5 {ECO:0000303|PubMed:23888068};
GN OrderedLocusNames=At4g15470 {ECO:0000312|Araport:AT4G15470};
GN ORFNames=dl3775w {ECO:0000312|EMBL:CAB10325.1},
GN FCAALL.58 {ECO:0000312|EMBL:CAB78589.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9461215; DOI=10.1038/35140;
RA Bevan M., Bancroft I., Bent E., Love K., Goodman H.M., Dean C.,
RA Bergkamp R., Dirkse W., van Staveren M., Stiekema W., Drost L., Ridley P.,
RA Hudson S.-A., Patel K., Murphy G., Piffanelli P., Wedler H., Wedler E.,
RA Wambutt R., Weitzenegger T., Pohl T., Terryn N., Gielen J., Villarroel R.,
RA De Clercq R., van Montagu M., Lecharny A., Aubourg S., Gy I., Kreis M.,
RA Lao N., Kavanagh T., Hempel S., Kotter P., Entian K.-D., Rieger M.,
RA Schaefer M., Funk B., Mueller-Auer S., Silvey M., James R., Monfort A.,
RA Pons A., Puigdomenech P., Douka A., Voukelatou E., Milioni D.,
RA Hatzopoulos P., Piravandi E., Obermaier B., Hilbert H., Duesterhoeft A.,
RA Moores T., Jones J.D.G., Eneva T., Palme K., Benes V., Rechmann S.,
RA Ansorge W., Cooke R., Berger C., Delseny M., Voet M., Volckaert G.,
RA Mewes H.-W., Klosterman S., Schueller C., Chalwatzis N.;
RT "Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis
RT thaliana.";
RL Nature 391:485-488(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11077244; DOI=10.1016/s1360-1385(00)01769-6;
RA Xiao W., Jang J.-C.;
RT "F-box proteins in Arabidopsis.";
RL Trends Plant Sci. 5:454-457(2000).
RN [6]
RP GENE FAMILY.
RX PubMed=19202280; DOI=10.1271/bbb.80752;
RA Yamagami A., Nakazawa M., Matsui M., Tujimoto M., Sakuta M., Asami T.,
RA Nakano T.;
RT "Chemical genetics reveal the novel transmembrane protein BIL4, which
RT mediates plant cell elongation in brassinosteroid signaling.";
RL Biosci. Biotechnol. Biochem. 73:415-421(2009).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=23888068; DOI=10.1093/jxb/ert217;
RA Weis C., Hueckelhoven R., Eichmann R.;
RT "LIFEGUARD proteins support plant colonization by biotrophic powdery mildew
RT fungi.";
RL J. Exp. Bot. 64:3855-3867(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the BI1 family. {ECO:0000305}.
CC -!- CAUTION: Was originally thought to contain a F-box domain and LRR
CC repeats, but it lacks both types of domains.
CC {ECO:0000305|PubMed:11077244}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAL07001.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=CAB10325.1; Type=Erroneous gene model prediction; Note=The predicted gene At4g15470 has been split into 2 genes: At4g15470 and At4g15475.; Evidence={ECO:0000305};
CC Sequence=CAB78589.1; Type=Erroneous gene model prediction; Note=The predicted gene At4g15470 has been split into 2 genes: At4g15470 and At4g15475.; Evidence={ECO:0000305};
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DR EMBL; Z97339; CAB10325.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161541; CAB78589.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE83607.1; -; Genomic_DNA.
DR EMBL; AY050443; AAK91458.1; -; mRNA.
DR EMBL; AY056115; AAL07001.1; ALT_FRAME; mRNA.
DR EMBL; AY097356; AAM19872.1; -; mRNA.
DR PIR; C71419; C71419.
DR RefSeq; NP_567466.1; NM_117636.3.
DR AlphaFoldDB; Q94A20; -.
DR SMR; Q94A20; -.
DR BioGRID; 12515; 1.
DR IntAct; Q94A20; 1.
DR STRING; 3702.AT4G15470.1; -.
DR iPTMnet; Q94A20; -.
DR PaxDb; Q94A20; -.
DR PRIDE; Q94A20; -.
DR ProteomicsDB; 250773; -.
DR EnsemblPlants; AT4G15470.1; AT4G15470.1; AT4G15470.
DR GeneID; 827218; -.
DR Gramene; AT4G15470.1; AT4G15470.1; AT4G15470.
DR KEGG; ath:AT4G15470; -.
DR Araport; AT4G15470; -.
DR TAIR; locus:2130190; AT4G15470.
DR eggNOG; KOG2322; Eukaryota.
DR HOGENOM; CLU_058671_0_1_1; -.
DR OMA; IYWLHML; -.
DR OrthoDB; 1290306at2759; -.
DR PhylomeDB; Q94A20; -.
DR PRO; PR:Q94A20; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q94A20; baseline and differential.
DR Genevisible; Q94A20; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR InterPro; IPR006214; Bax_inhibitor_1-related.
DR PANTHER; PTHR23291; PTHR23291; 1.
DR Pfam; PF01027; Bax1-I; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..256
FT /note="BI1-like protein"
FT /id="PRO_0000272240"
FT TRANSMEM 53..73
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 85..105
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 138..158
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 167..187
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 189..209
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 228..248
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 256 AA; 28168 MW; C0557CB93A5B7024 CRC64;
MDKPYGYASV SMSGIDRSAG KDIDLEMGVG EATLYPGLSY GENQLRWGFI RKVYGILSAQ
LLLTTLISAV VVLNPPVNDL LTGSPGILLF LCIVPFILIW PLHIYHQKHP VNLILLALFT
VSLSFTVGVS CAMTEGRIVL QALILTLSVV GSLTAYTFWA AKKGKDFSFL GPILFTSLII
LVVTSFIQMF FPLGPTSVAV YGGFSALVFC GYIVYDTDNL IKRFTYDEYI LASVALYLDI
LNLFLTILRI LRQGDN
