LFL1_ORYSJ
ID LFL1_ORYSJ Reviewed; 402 AA.
AC A4LBC0; Q5N8D2;
DT 16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2007, sequence version 1.
DT 03-AUG-2022, entry version 85.
DE RecName: Full=B3 domain-containing protein LFL1;
DE AltName: Full=LEC2 and FUSCA3-like protein 1;
DE Short=OsLFL1;
GN Name=LFL1; OrderedLocusNames=Os01g0713600, LOC_Os01g51610;
GN ORFNames=B1142C05.32;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, SUBCELLULAR LOCATION, AND TISSUE
RP SPECIFICITY.
RC STRAIN=cv. Zhonghua 11;
RX PubMed=17913295; DOI=10.1016/j.jplph.2007.07.010;
RA Peng L.-T., Shi Z.-Y., Li L., Shen G.-Z., Zhang J.-L.;
RT "Overexpression of transcription factor OsLFL1 delays flowering time in
RT Oryza sativa.";
RL J. Plant Physiol. 165:876-885(2008).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 80-402.
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP FUNCTION.
RX PubMed=17592727; DOI=10.1016/j.bbrc.2007.06.041;
RA Peng L.-T., Shi Z.-Y., Li L., Shen G.-Z., Zhang J.-L.;
RT "Ectopic expression of OsLFL1 in rice represses Ehd1 by binding on its
RT promoter.";
RL Biochem. Biophys. Res. Commun. 360:251-256(2007).
CC -!- FUNCTION: Transcription repressor involved in flowering time
CC regulation. Represses the flowering activator EHD1 by binding
CC specifically to the DNA sequence 5'-CATGCATG-3 of its promoter.
CC {ECO:0000269|PubMed:17592727, ECO:0000269|PubMed:17913295}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00326,
CC ECO:0000269|PubMed:17913295}.
CC -!- TISSUE SPECIFICITY: Expressed in anthers, pollen grains and young
CC developing embryos. {ECO:0000269|PubMed:17913295}.
CC -!- MISCELLANEOUS: Plants overexpressing LFL1 show a late-flowering
CC phenotype.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAD82277.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=BAF05967.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=BAG98960.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; EF521182; ABO64645.1; -; mRNA.
DR EMBL; AP003410; BAD82277.1; ALT_INIT; Genomic_DNA.
DR EMBL; AP008207; BAF05967.1; ALT_INIT; Genomic_DNA.
DR EMBL; AP014957; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AK109920; BAG98960.1; ALT_INIT; mRNA.
DR RefSeq; XP_015635173.1; XM_015779687.1.
DR AlphaFoldDB; A4LBC0; -.
DR SMR; A4LBC0; -.
DR STRING; 4530.OS01T0713600-01; -.
DR PaxDb; A4LBC0; -.
DR PRIDE; A4LBC0; -.
DR EnsemblPlants; Os01t0713600-01; Os01t0713600-01; Os01g0713600.
DR GeneID; 4325939; -.
DR Gramene; Os01t0713600-01; Os01t0713600-01; Os01g0713600.
DR KEGG; osa:4325939; -.
DR eggNOG; ENOG502QPW6; Eukaryota.
DR HOGENOM; CLU_058916_0_0_1; -.
DR InParanoid; A4LBC0; -.
DR OrthoDB; 317013at2759; -.
DR PlantReactome; R-OSA-8934036; Long day regulated expression of florigens.
DR PlantReactome; R-OSA-9631623; Regulation of embryo development.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR Genevisible; A4LBC0; OS.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IDA:UniProtKB.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IDA:UniProtKB.
DR GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR GO; GO:0048573; P:photoperiodism, flowering; IMP:UniProtKB.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR CDD; cd10017; B3_DNA; 1.
DR Gene3D; 2.40.330.10; -; 1.
DR InterPro; IPR003340; B3_DNA-bd.
DR InterPro; IPR015300; DNA-bd_pseudobarrel_sf.
DR InterPro; IPR044800; LEC2-like.
DR PANTHER; PTHR31140; PTHR31140; 1.
DR Pfam; PF02362; B3; 1.
DR SMART; SM01019; B3; 1.
DR SUPFAM; SSF101936; SSF101936; 1.
DR PROSITE; PS50863; B3; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Flowering; Nucleus; Reference proteome; Repressor;
KW Transcription; Transcription regulation.
FT CHAIN 1..402
FT /note="B3 domain-containing protein LFL1"
FT /id="PRO_0000378040"
FT DNA_BIND 181..284
FT /note="TF-B3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00326"
FT REGION 1..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 381..402
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..105
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 106..136
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 402 AA; 43409 MW; 0C26DF2DBCE7F67E CRC64;
MRGEERWQEQ PALASHPSRA TLRPRGWPRL GLAPTGVGSS CPPAPASELA RHLARRAPVS
ASPPVLPPIK DQGARPPTLA ASAAAASSPP PPPPPPIPPL PPSTSTSAAR PTDMAGVTSK
RRSSSASTSS SSGDGAAVSD RPRGVTRKRR SGGRCPRPAA SLRPAAPRPS SHHTAGLRVI
LQKELRYSDV SQLGRIVLPK KEAEAYLPIL TSKDGKKSLC MHDLQNAQLW TFKYRYWPNN
KSRMYVLENT GDYVRTHDLQ LGDSIVIYKD DENNRFVIGA KKAGDQQAAT VPQVDEHIST
LFPIFPIAQV DDYLSPMAPQ VDISAFVPHA DENHEIFDGI LNSLPEIPVA NVRYSDFFDP
FDDGMDMANT LNANANQSAS LHVTDDKSGH SLIPNPKSGP HM
