LG2_MAIZE
ID LG2_MAIZE Reviewed; 531 AA.
AC O49067;
DT 15-FEB-2017, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 25-MAY-2022, entry version 123.
DE RecName: Full=Transcription factor LG2 {ECO:0000303|PubMed:9490265};
DE AltName: Full=Protein LIGULELESS 2 {ECO:0000303|PubMed:9490265};
DE AltName: Full=Protein TGACG (TGA) motif-binding protein LG2 {ECO:0000303|PubMed:9490265};
GN Name=LG2 {ECO:0000303|PubMed:9490265};
GN ORFNames=GRMZM2G060216 {ECO:0000312|EMBL:AAO45627.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, DISRUPTION PHENOTYPE, AND TISSUE
RP SPECIFICITY.
RX PubMed=9490265; DOI=10.1101/gad.12.2.208;
RA Walsh J., Waters C.A., Freeling M.;
RT "The maize gene liguleless2 encodes a basic leucine zipper protein involved
RT in the establishment of the leaf blade-sheath boundary.";
RL Genes Dev. 12:208-218(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. B73;
RX PubMed=19965430; DOI=10.1126/science.1178534;
RA Schnable P.S., Ware D., Fulton R.S., Stein J.C., Wei F., Pasternak S.,
RA Liang C., Zhang J., Fulton L., Graves T.A., Minx P., Reily A.D.,
RA Courtney L., Kruchowski S.S., Tomlinson C., Strong C., Delehaunty K.,
RA Fronick C., Courtney B., Rock S.M., Belter E., Du F., Kim K., Abbott R.M.,
RA Cotton M., Levy A., Marchetto P., Ochoa K., Jackson S.M., Gillam B.,
RA Chen W., Yan L., Higginbotham J., Cardenas M., Waligorski J., Applebaum E.,
RA Phelps L., Falcone J., Kanchi K., Thane T., Scimone A., Thane N., Henke J.,
RA Wang T., Ruppert J., Shah N., Rotter K., Hodges J., Ingenthron E.,
RA Cordes M., Kohlberg S., Sgro J., Delgado B., Mead K., Chinwalla A.,
RA Leonard S., Crouse K., Collura K., Kudrna D., Currie J., He R.,
RA Angelova A., Rajasekar S., Mueller T., Lomeli R., Scara G., Ko A.,
RA Delaney K., Wissotski M., Lopez G., Campos D., Braidotti M., Ashley E.,
RA Golser W., Kim H., Lee S., Lin J., Dujmic Z., Kim W., Talag J., Zuccolo A.,
RA Fan C., Sebastian A., Kramer M., Spiegel L., Nascimento L., Zutavern T.,
RA Miller B., Ambroise C., Muller S., Spooner W., Narechania A., Ren L.,
RA Wei S., Kumari S., Faga B., Levy M.J., McMahan L., Van Buren P.,
RA Vaughn M.W., Ying K., Yeh C.-T., Emrich S.J., Jia Y., Kalyanaraman A.,
RA Hsia A.-P., Barbazuk W.B., Baucom R.S., Brutnell T.P., Carpita N.C.,
RA Chaparro C., Chia J.-M., Deragon J.-M., Estill J.C., Fu Y., Jeddeloh J.A.,
RA Han Y., Lee H., Li P., Lisch D.R., Liu S., Liu Z., Nagel D.H., McCann M.C.,
RA SanMiguel P., Myers A.M., Nettleton D., Nguyen J., Penning B.W.,
RA Ponnala L., Schneider K.L., Schwartz D.C., Sharma A., Soderlund C.,
RA Springer N.M., Sun Q., Wang H., Waterman M., Westerman R., Wolfgruber T.K.,
RA Yang L., Yu Y., Zhang L., Zhou S., Zhu Q., Bennetzen J.L., Dawe R.K.,
RA Jiang J., Jiang N., Presting G.G., Wessler S.R., Aluru S.,
RA Martienssen R.A., Clifton S.W., McCombie W.R., Wing R.A., Wilson R.K.;
RT "The B73 maize genome: complexity, diversity, and dynamics.";
RL Science 326:1112-1115(2009).
CC -!- FUNCTION: Required for the formation of the blade-sheath boundary in
CC leaves. Promotes flowering. {ECO:0000269|PubMed:9490265}.
CC -!- SUBUNIT: Binds DNA as a dimer. {ECO:0000250|UniProtKB:Q39140}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768,
CC ECO:0000255|PROSITE-ProRule:PRU00978}.
CC -!- TISSUE SPECIFICITY: Expression in meristem/developing ligule regions.
CC {ECO:0000269|PubMed:9490265}.
CC -!- DISRUPTION PHENOTYPE: Defects in the formation of the blade-sheath
CC boundary in leaves (e.g. absent or incorrectly positioned ligule and
CC auricles) and delayed flowering. {ECO:0000269|PubMed:9490265}.
CC -!- SIMILARITY: Belongs to the bZIP family. {ECO:0000305}.
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DR EMBL; AF036949; AAC39351.1; -; mRNA.
DR EMBL; AY180106; AAO45627.1; -; Genomic_DNA.
DR PIR; T01415; T01415.
DR RefSeq; NP_001104893.1; NM_001111423.1.
DR AlphaFoldDB; O49067; -.
DR STRING; 4577.GRMZM2G060216_P01; -.
DR PaxDb; O49067; -.
DR EnsemblPlants; Zm00001eb147220_T001; Zm00001eb147220_P001; Zm00001eb147220.
DR GeneID; 541670; -.
DR Gramene; Zm00001eb147220_T001; Zm00001eb147220_P001; Zm00001eb147220.
DR KEGG; zma:541670; -.
DR MaizeGDB; 219512; -.
DR eggNOG; ENOG502QRFK; Eukaryota.
DR HOGENOM; CLU_024782_0_2_1; -.
DR Proteomes; UP000007305; Chromosome 3.
DR ExpressionAtlas; O49067; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:1905623; P:positive regulation of leaf development; IMP:UniProtKB.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR InterPro; IPR025422; TGA_domain.
DR Pfam; PF00170; bZIP_1; 1.
DR Pfam; PF14144; DOG1; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; SSF57959; 1.
DR PROSITE; PS50217; BZIP; 1.
DR PROSITE; PS00036; BZIP_BASIC; 1.
DR PROSITE; PS51806; DOG1; 1.
PE 2: Evidence at transcript level;
KW Activator; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..531
FT /note="Transcription factor LG2"
FT /id="PRO_0000438996"
FT DOMAIN 220..264
FT /note="bZIP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT DOMAIN 285..499
FT /note="DOG1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01147"
FT REGION 115..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 222..242
FT /note="Basic motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 248..262
FT /note="Leucine-zipper"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT MOTIF 224..231
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00768"
FT COMPBIAS 199..220
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 531 AA; 57680 MW; C34353E459079BA1 CRC64;
MVQGEESSWR MERAALPLNQ ALAYGVQAHA AAAAAPPTCF LDFQPAAASA AYFGFGELEE
ALIHGGGAAS AGGGVDPGVI IKNDVAQAKS AAGYLAGAGT GRPPTLEIFP SWPMRHQQQL
HSGNSQSVGS TGTDSSSAQN TMSQMELVSP ASSAPRQEVM MVTTDDYSYK PGLAAAPAAA
APPSFQQHHP LPLQLHGGEG GGDHDKRKHG STRKDGKLVD AKTERRLAQN REAARKSRLR
KKAYVQQLET SRIRLQQVEH ELQRARSQGL FVGGCSAAGD MSSGAAMFDM EYARWLDDDT
KRLAELRGGL QAHLLDGNLG LIVEECMQHY DELFQLKAAL ARSDVFHLLT GSWATPAERC
FFWMGGFRPS ELLKILIPQL DPLTEQQLLG ICNLQQSSEQ AEEALAQGLH QLHQSLADTV
AAGTLNDGAA APNYMNIMAV ALEKLASLEN FYQQADNLRH QTLHQMRRIL TTRQAARCFL
SIGEYYSRLR ALSNLWASRP RDNFIGTESL SPTATELQAL HHQQQNQFAG F
