ID   LGB1_MEDTR              Reviewed;         147 AA.
AC   P27992;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Leghemoglobin 1;
GN   Name=LB1;
OS   Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX   NCBI_TaxID=3880;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=cv. Jemalong; TISSUE=Root nodule;
RX   PubMed=1883994; DOI=10.1007/bf00040629;
RA   Gallusci P., Dedieu A., Journet E.P., Huguet T., Barker D.G.;
RT   "Synchronous expression of leghaemoglobin genes in Medicago truncatula
RT   during nitrogen-fixing root nodule development and response to exogenously
RT   supplied nitrate.";
RL   Plant Mol. Biol. 17:335-349(1991).
CC   -!- FUNCTION: Provides oxygen to the bacteroids. This role is essential for
CC       symbiotic nitrogen fixation.
CC   -!- SUBUNIT: Monomer.
CC   -!- TISSUE SPECIFICITY: Root nodules.
CC   -!- SIMILARITY: Belongs to the plant globin family. {ECO:0000305}.
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DR   EMBL; X57732; CAA40899.1; -; Genomic_DNA.
DR   PIR; S17438; S17438.
DR   RefSeq; XP_003615280.1; XM_003615232.2.
DR   AlphaFoldDB; P27992; -.
DR   SMR; P27992; -.
DR   STRING; 3880.AES98238; -.
DR   ProMEX; P27992; -.
DR   EnsemblPlants; AES98238; AES98238; MTR_5g066070.
DR   GeneID; 11435509; -.
DR   Gramene; AES98238; AES98238; MTR_5g066070.
DR   eggNOG; KOG3378; Eukaryota.
DR   HOGENOM; CLU_003827_11_2_1; -.
DR   OMA; LIMERAP; -.
DR   OrthoDB; 696109at2759; -.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.490.10; -; 1.
DR   InterPro; IPR000971; Globin.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012292; Globin/Proto.
DR   InterPro; IPR001032; Leghaemoglobin.
DR   InterPro; IPR019824; Leghaemoglobin_Fe_BS.
DR   PANTHER; PTHR22924; PTHR22924; 1.
DR   Pfam; PF00042; Globin; 1.
DR   SUPFAM; SSF46458; SSF46458; 1.
DR   PROSITE; PS01033; GLOBIN; 1.
DR   PROSITE; PS00208; PLANT_GLOBIN; 1.
PE   2: Evidence at transcript level;
KW   Heme; Iron; Metal-binding; Nitrogen fixation; Oxygen transport; Transport.
FT   CHAIN           1..147
FT                   /note="Leghemoglobin 1"
FT                   /id="PRO_0000192989"
FT   BINDING         62
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="distal binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00238"
FT   BINDING         94
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="proximal binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00238"
SQ   SEQUENCE   147 AA;  15841 MW;  FA78C20E38FD9E01 CRC64;
     MSFTDKQEAL VNSSYEAFKQ NLSGYSVFFY TVILEKAPAA KGLFSFLKDS AGVQDSPQLQ
     AHAEKVFGLV RDSASQLRAT GGVVLGDAAL GAIHIQKGVV DPHFVVVKEA LLKTIKEAAG
     DKWSEELSTA WEVAYDALAT EIKKAMS