LH3_ADES1
ID LH3_ADES1 Reviewed; 373 AA.
AC A9CB85;
DT 19-MAR-2014, integrated into UniProtKB/Swiss-Prot.
DT 15-JAN-2008, sequence version 1.
DT 29-SEP-2021, entry version 44.
DE RecName: Full=Hexon-interlacing protein LH3;
OS Snake adenovirus serotype 1 (SnAdV-1).
OC Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes;
OC Rowavirales; Adenoviridae; Atadenovirus.
OX NCBI_TaxID=189830;
OH NCBI_TaxID=94885; Pantherophis guttatus (Corn snake) (Elaphe guttata).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=12237421; DOI=10.1099/0022-1317-83-10-2403;
RA Farkas S.L., Benko M., Elo P.T., Ursu K., Dan A., Ahne W., Harrach B.;
RT "Genetic analysis of an adenovirus isolated from corn snake (Elaphe
RT guttata) implies common origin with the members of the proposed new genus
RT Atadenovirus.";
RL J. Gen. Virol. 83:2403-2410(2002).
CC -!- FUNCTION: Structural component of the virion that presumably stabilizes
CC the groups of hexons but is dispensable for assembly. {ECO:0000250}.
CC -!- SUBUNIT: Homotrimer. Interacts with hexon protein; this interaction
CC tethers the hexons together (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the atadenoviridae LH3 protein family.
CC {ECO:0000305}.
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DR EMBL; DQ106414; ABA47235.1; -; Genomic_DNA.
DR RefSeq; YP_001552245.1; NC_009989.1.
DR PDB; 5G5N; X-ray; 2.30 A; A/B/C=21-373.
DR PDB; 5G5O; X-ray; 2.00 A; A/B/C/D/E/F=1-373.
DR PDBsum; 5G5N; -.
DR PDBsum; 5G5O; -.
DR SMR; A9CB85; -.
DR GeneID; 10973887; -.
DR KEGG; vg:10973887; -.
DR Proteomes; UP000136605; Genome.
DR Gene3D; 2.160.20.10; -; 1.
DR InterPro; IPR012334; Pectin_lyas_fold.
DR InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR SUPFAM; SSF51126; SSF51126; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; Virion.
FT CHAIN 1..373
FT /note="Hexon-interlacing protein LH3"
FT /id="PRO_0000425920"
FT HELIX 37..43
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 45..49
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 54..56
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 59..62
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 67..69
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 74..76
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 83..87
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 96..100
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 102..104
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 106..108
FT /evidence="ECO:0007829|PDB:5G5N"
FT HELIX 117..120
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 124..129
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 132..136
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 138..140
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 143..150
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 157..159
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 166..169
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 171..174
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 176..181
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 189..192
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 194..197
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 199..204
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 210..213
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 215..218
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 220..228
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 239..241
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 243..247
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 249..257
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 262..265
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 270..272
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 275..279
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 287..290
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 292..295
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 298..302
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 309..313
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 315..317
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 320..324
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 326..328
FT /evidence="ECO:0007829|PDB:5G5O"
FT HELIX 330..335
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 336..340
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 348..352
FT /evidence="ECO:0007829|PDB:5G5O"
FT HELIX 354..356
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 357..359
FT /evidence="ECO:0007829|PDB:5G5O"
FT STRAND 362..365
FT /evidence="ECO:0007829|PDB:5G5O"
SQ SEQUENCE 373 AA; 40797 MW; 1D0307BAA079C4DB CRC64;
MTSVEDLYVV KPINQWPAPS AFLYPLPRGT LLPGQSPDEA FARNSVVFLV PGAEYNWKNV
VIRKPVWIYG ERCHGEDFRP RAIIHIMGDL DNPMDVRIQD LTFIGGDSPD RLVPFSAVLT
NQMALWCIDP RITIRGCSFY NFGGAAIYLE RSERDTGFRF GRGQVMITDC RFRGCRIGIA
NGGSVEYGLA SQNNFSDCQI CFNVVGGNWT RSGNVASNCR CMYLHTQGMW YEGAAGNFNP
AHGSFTSNTL NHCDYGGNLW PTEFQLPDRV INLAGFYFDN AAARLPNFSG NSQWYGDMKL
INFLPDSTFV INGGALYGGP GDTGVIAVAT ALAAKVFVIG CQGNAGQQIV NVPAANIIPE
VGTRKDDATQ PAA