ID   LHPL3_DANRE             Reviewed;         216 AA.
AC   Q6DHB5;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=LHFPL tetraspan subfamily member 3 protein {ECO:0000250|UniProtKB:Q86UP9};
DE   AltName: Full=Lipoma HMGIC fusion partner-like 3 protein {ECO:0000250|UniProtKB:Q86UP9};
GN   Name=lhfpl3 {ECO:0000250|UniProtKB:Q86UP9}; ORFNames=zgc:92534;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen;
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA   Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA   Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA   White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA   Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA   Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA   Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA   Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA   Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA   Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA   Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA   McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA   Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA   Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA   Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA   Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA   Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA   Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA   Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA   Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA   Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA   Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA   de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA   Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the human
RT   genome.";
RL   Nature 496:498-503(2013).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the LHFP family. {ECO:0000305}.
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DR   EMBL; BX537162; CAK11284.1; -; Genomic_DNA.
DR   EMBL; BC076060; AAH76060.1; -; mRNA.
DR   RefSeq; NP_001003444.1; NM_001003444.1.
DR   AlphaFoldDB; Q6DHB5; -.
DR   SMR; Q6DHB5; -.
DR   STRING; 7955.ENSDARP00000038316; -.
DR   PaxDb; Q6DHB5; -.
DR   Ensembl; ENSDART00000039277; ENSDARP00000038316; ENSDARG00000021595.
DR   GeneID; 445050; -.
DR   KEGG; dre:445050; -.
DR   CTD; 375612; -.
DR   ZFIN; ZDB-GENE-040801-180; lhfpl3.
DR   eggNOG; KOG4026; Eukaryota.
DR   GeneTree; ENSGT00990000203541; -.
DR   HOGENOM; CLU_084868_1_2_1; -.
DR   InParanoid; Q6DHB5; -.
DR   OMA; QDNLMSE; -.
DR   OrthoDB; 1219117at2759; -.
DR   PhylomeDB; Q6DHB5; -.
DR   TreeFam; TF321143; -.
DR   PRO; PR:Q6DHB5; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 4.
DR   Bgee; ENSDARG00000021595; Expressed in brain and 8 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0007605; P:sensory perception of sound; IBA:GO_Central.
DR   InterPro; IPR019372; LHFPL.
DR   PANTHER; PTHR12489; PTHR12489; 1.
DR   Pfam; PF10242; L_HMGIC_fpl; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..216
FT                   /note="LHFPL tetraspan subfamily member 3 protein"
FT                   /id="PRO_0000244768"
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        96..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        126..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        177..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   216 AA;  23499 MW;  F357C43CECB4BDAC CRC64;
     MLPATEAAKI YQTNYVRNSR AIGVLWAIFT TLFAIVNVVC FVQPYWIGDG MDTPQAGYFG
     LFHYCIGSGM SRDLTCQGSF TEFGSIPSSA FKAASFFIGM SMVLVLSCIG CFALFFFCST
     ATVYKICGWM QLAAGTCLVL GCMIYPDGWD ADEVKRMCGE GTDKYTIGAC SVRWAYILAI
     MGILDALILS FLAFVLGNRQ DGLMSEELLG DKSGNA