LHPL6_DANRE
ID LHPL6_DANRE Reviewed; 200 AA.
AC Q5PRC1;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 04-JAN-2005, sequence version 1.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=LHFPL tetraspan subfamily member 6 protein {ECO:0000250|UniProtKB:Q9Y693};
DE Flags: Precursor;
GN Name=lhfpl6 {ECO:0000250|UniProtKB:Q9Y693}; ORFNames=zgc:101683;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Olfactory epithelium;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the LHFP family. {ECO:0000305}.
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DR EMBL; BC086720; AAH86720.1; -; mRNA.
DR RefSeq; NP_001008653.1; NM_001008653.1.
DR AlphaFoldDB; Q5PRC1; -.
DR SMR; Q5PRC1; -.
DR STRING; 7955.ENSDARP00000007599; -.
DR PaxDb; Q5PRC1; -.
DR Ensembl; ENSDART00000019416; ENSDARP00000007599; ENSDARG00000004363.
DR Ensembl; ENSDART00000182579; ENSDARP00000149721; ENSDARG00000004363.
DR Ensembl; ENSDART00000185634; ENSDARP00000147943; ENSDARG00000004363.
DR GeneID; 494110; -.
DR KEGG; dre:494110; -.
DR CTD; 10186; -.
DR ZFIN; ZDB-GENE-041212-82; lhfpl6.
DR eggNOG; KOG4026; Eukaryota.
DR GeneTree; ENSGT00990000203589; -.
DR HOGENOM; CLU_084868_2_0_1; -.
DR InParanoid; Q5PRC1; -.
DR OMA; ITVMVEQ; -.
DR OrthoDB; 1383327at2759; -.
DR PhylomeDB; Q5PRC1; -.
DR TreeFam; TF321143; -.
DR ChiTaRS; lhfp; zebrafish.
DR PRO; PR:Q5PRC1; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 10.
DR Bgee; ENSDARG00000004363; Expressed in swim bladder and 35 other tissues.
DR ExpressionAtlas; Q5PRC1; baseline.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR InterPro; IPR019372; LHFPL.
DR PANTHER; PTHR12489; PTHR12489; 1.
DR Pfam; PF10242; L_HMGIC_fpl; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..200
FT /note="LHFPL tetraspan subfamily member 6 protein"
FT /id="PRO_0000244759"
FT TRANSMEM 84..104
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 123..143
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CARBOHYD 154
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 200 AA; 21368 MW; 3C222E62BA39D3D2 CRC64;
MASSLTCAGV IWALLSFLCA ATSCVGFFMP YWLLGSQMGK PVSFGTFRRC SYPIRDEARG
GTVMLEQCGR YASFQGIPSL EWRICTVVTG IGCGLLLLVA LTAIMGCCVT DLISRTIGRV
AGGIQFVGGL LIGSGCALYP LGWDSEEVRQ TCSNSSDQFD LGSCEIGWAY YCTGAGAAAA
MVLCTWMACF AGKKQKHYPY