ID   LHPL6_RAT               Reviewed;         200 AA.
AC   Q5BJS2;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   12-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=LHFPL tetraspan subfamily member 6 protein {ECO:0000312|RGD:1560177};
DE   AltName: Full=Lipoma HMGIC fusion partner {ECO:0000250|UniProtKB:Q9Y693};
DE   Flags: Precursor;
GN   Name=Lhfpl6 {ECO:0000312|RGD:1560177};
GN   Synonyms=Lhfp {ECO:0000250|UniProtKB:Q8BM86};
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the LHFP family. {ECO:0000305}.
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DR   EMBL; BC091355; AAH91355.1; -; mRNA.
DR   RefSeq; NP_001102653.1; NM_001109183.1.
DR   AlphaFoldDB; Q5BJS2; -.
DR   SMR; Q5BJS2; -.
DR   STRING; 10116.ENSRNOP00000019057; -.
DR   PhosphoSitePlus; Q5BJS2; -.
DR   PaxDb; Q5BJS2; -.
DR   Ensembl; ENSRNOT00000117418; ENSRNOP00000092096; ENSRNOG00000014153.
DR   GeneID; 499615; -.
DR   KEGG; rno:499615; -.
DR   UCSC; RGD:1560177; rat.
DR   CTD; 10186; -.
DR   RGD; 1560177; Lhfpl6.
DR   eggNOG; KOG4026; Eukaryota.
DR   GeneTree; ENSGT00990000203589; -.
DR   HOGENOM; CLU_084868_2_0_1; -.
DR   InParanoid; Q5BJS2; -.
DR   OMA; ITVMVEQ; -.
DR   OrthoDB; 1383327at2759; -.
DR   PhylomeDB; Q5BJS2; -.
DR   TreeFam; TF321143; -.
DR   PRO; PR:Q5BJS2; -.
DR   Proteomes; UP000002494; Chromosome 2.
DR   Bgee; ENSRNOG00000014153; Expressed in lung and 19 other tissues.
DR   Genevisible; Q5BJS2; RN.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   InterPro; IPR019372; LHFPL.
DR   PANTHER; PTHR12489; PTHR12489; 1.
DR   Pfam; PF10242; L_HMGIC_fpl; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..200
FT                   /note="LHFPL tetraspan subfamily member 6 protein"
FT                   /id="PRO_0000244758"
FT   TRANSMEM        84..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        123..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        166..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   200 AA;  21666 MW;  B79B0214F15FB3A1 CRC64;
     MASSLTCTGV IWALLSFLSA ATSCVGFFMP YWLWGSQLGK PVSFGTFRRC SYPVHDESRQ
     MMVMVEECGR YASFQGIPST EWRICTIVTG LGCGLLLLVA LTALMGCCVS ELISRTVGRV
     AGGIQFLGGL LIGAGCALYP LGWDSEEVRQ TCGYISDQFD LGKCEIGWAY YCTGAGAAAA
     MLLCTWLACF SGKKQKHYPY