LHPL7_MOUSE
ID LHPL7_MOUSE Reviewed; 195 AA.
AC Q3UUA0; B9EJN6;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=LHFPL tetraspan subfamily member 7 protein;
DE AltName: Full=Transmembrane protein 211;
GN Name=Lhfpl7; Synonyms=Gm854, Tmem211;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Spinal cord;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TMEM211 family. {ECO:0000305}.
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DR EMBL; AK138479; BAE23675.1; -; mRNA.
DR EMBL; AK138629; BAE23727.1; -; mRNA.
DR EMBL; BC147409; AAI47410.1; -; mRNA.
DR EMBL; BC147410; AAI47411.1; -; mRNA.
DR CCDS; CCDS19548.1; -.
DR RefSeq; NP_001028600.1; NM_001033428.2.
DR RefSeq; XP_006535084.1; XM_006535021.2.
DR AlphaFoldDB; Q3UUA0; -.
DR SMR; Q3UUA0; -.
DR STRING; 10090.ENSMUSP00000083808; -.
DR iPTMnet; Q3UUA0; -.
DR PhosphoSitePlus; Q3UUA0; -.
DR PaxDb; Q3UUA0; -.
DR PRIDE; Q3UUA0; -.
DR Antibodypedia; 74015; 4 antibodies from 4 providers.
DR Ensembl; ENSMUST00000086615; ENSMUSP00000083808; ENSMUSG00000066964.
DR GeneID; 333048; -.
DR KEGG; mmu:333048; -.
DR UCSC; uc008yub.1; mouse.
DR CTD; 333048; -.
DR MGI; MGI:2685700; Tmem211.
DR VEuPathDB; HostDB:ENSMUSG00000066964; -.
DR eggNOG; KOG4026; Eukaryota.
DR GeneTree; ENSGT00990000203589; -.
DR HOGENOM; CLU_1421051_0_0_1; -.
DR InParanoid; Q3UUA0; -.
DR OMA; FAKEACG; -.
DR OrthoDB; 1449971at2759; -.
DR PhylomeDB; Q3UUA0; -.
DR TreeFam; TF343322; -.
DR BioGRID-ORCS; 333048; 3 hits in 75 CRISPR screens.
DR PRO; PR:Q3UUA0; -.
DR Proteomes; UP000000589; Chromosome 5.
DR RNAct; Q3UUA0; protein.
DR Bgee; ENSMUSG00000066964; Expressed in ectoplacental cone and 3 other tissues.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR InterPro; IPR019372; LHFPL.
DR PANTHER; PTHR12489; PTHR12489; 1.
DR Pfam; PF10242; L_HMGIC_fpl; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..195
FT /note="LHFPL tetraspan subfamily member 7 protein"
FT /id="PRO_0000337009"
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 73..93
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 108..128
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 149..169
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 195 AA; 20752 MW; C2AB81CA7BDA281D CRC64;
MEVGVRAALG LSLTGMSGLS LISPAWFQSL SSSYGIFTYC SWPPGDCWNQ SCVTFGSLKD
MPSLAWKVSA ATLLGGWLLL SISALLLSAW ALAPRRLFAR TGFGPTPVVQ AAAAVSMLVG
LLVFPATLAS PFAKEICEGS SMYHSGACRL SWGYATAILN MVLTSLLVIR WQVTTVQRAA
VPFSSETQRA ILVPE
