ID   LIFO_PSEWI              Reviewed;         352 AA.
AC   O05938;
DT   20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Lipase chaperone;
DE   AltName: Full=Lipase activator protein;
DE   AltName: Full=Lipase foldase;
DE   AltName: Full=Lipase helper protein;
DE   AltName: Full=Lipase modulator;
GN   Name=lifO; Synonyms=lipB, lpwB;
OS   Pseudomonas wisconsinensis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=57038;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LMG P-15151;
RA   Hazbon M.H., Dufel H., Cornelis P., Jaeger K.-E.;
RT   "Molecular characterization of an operon from Pseudomonas wisconsinensis
RT   responsible for the production of an extracellular lipase.";
RL   Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in the folding of the extracellular lipase
CC       during its passage through the periplasm. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Single-pass
CC       membrane protein {ECO:0000250}; Periplasmic side {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the lipase chaperone family. {ECO:0000305}.
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DR   EMBL; U88907; AAB53648.1; -; Genomic_DNA.
DR   AlphaFoldDB; O05938; -.
DR   SMR; O05938; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00790; Lipase_chap; 1.
DR   InterPro; IPR004961; Lipase_chaperone.
DR   Pfam; PF03280; Lipase_chap; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Chaperone; Lipid degradation;
KW   Lipid metabolism; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..352
FT                   /note="Lipase chaperone"
FT                   /id="PRO_0000218486"
FT   TRANSMEM        7..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   352 AA;  39574 MW;  592559094CE13EC9 CRC64;
     MSKFFSLSLV AVVVAGGLTL YWRWPAAVPE AQPATTVAVP SRQSLIEQAS TSPAKAPAEA
     QPSIAVTLPS LAGTEVDGQL RTDAAGNLLL DLAVRDYFDY FLSAVDHSGL DAVIEALLAD
     AGRRLPEPAL GQMISLLGDY LDYKRASMAL MQQPLDARQQ VEPQAQLQAL QSAFARLDEL
     RRAHFSATAQ EALFGAEQAY ARYTLDSLAV QQRDDLGEAQ RTQLLEQLRE RLPDALRESE
     QRQQLAQEQL QRSEQLWRDG ADEQQVREFL AMTYDPDTVQ RLLDEQRRER DWQQHYQAYR
     NELASLQGRG LSEADGEQLQ RQLRERLFSS EDRHRVETYD AIAAKQPEPL DP